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Biomedical subjects

R W Parsons

Publications and source records attributed to R W Parsons.

At least 55 records · Page 3Linked to original sources

Amniotic membranes as dressings following facial dermabrasion.

Facial dermabrasion produces a raw, painful, partial-thickness wound, quite similar to a split-thickness skin graft donor site. The various methods of dressing such wounds employing ointments, impregnated gauze, bulky absorptive dressings, xenografts, or allografts are time consuming, uncomfortable for the patient, and not infrequently characterized by localized purulence and delayed healing. Experience with amniotic membranes as biologic dressings, both experimental and clinical, prompted a trial of these membranes as a dressing following facial dermabrasion. Thirty-three patients undergoing facial dermabrasion were dressed with amniotic membranes following the procedures. The results following this dressing method were excellent. The biologic basis and the techniques of preparing and applying amniotic membranes as dressings following facial dermabrasion are presented. The advantages of amniotic membranes over the other presently employed dressing techniques following facial dermabrasion are discussed.

Amnion↗

Rule of thumb criteria for tongue-lip adhesion in Pierre Robin anomalad.

Rule of thumb criteria for tongue-lip adhesion in the Pierre Robin anomalad have been formulated on the basis of a review of 38 cases. Babies with this anomalad who do not show a progressive gain in strength and weight after 7 days of nonoperative intensive care or who cannot be successfully extubated after 3 days should have a tongue-lip adhesion as the next step in conservative management.

Body Weight↗

Methods and results of reconstruction with free flaps following resection of squamous cell carcinoma of the head and neck.

Our experience with 9 patients who have undergone reconstruction with free flap transfers following resection of squamous cell carcinoma in the head and neck area is presented. The dorsalis pedis flap was used in 3 patients, the iliofemoral (groin) flap in 4, and the latissimus dorsi myocutaneous flap in 2. Four patients had received preoperative irradiation. Despite minor partial flap necrosis in 3 patients and the development of oral cutaneous fistulas in 2, all the flaps were successful in providing the necessary coverage. Reoperation in 1 patient was necessary because of thrombosis of the venous anastomosis.

Adult↗

Polymyositis, prednisone, and pheomycotic cyst.

An immunosuppressed patient with polymyositis presented with an apparent ganglion of the left foot. During the operative procedure, a cystic mass inconsistent with a ganglion was excised and immediately sent to the Quantitative Bacteriology Laboratory. A rapid slide examination revealed yeastlike bodies present in the tissue. The remainder of the tissue was sent to pathology for special staining. The H&E and GMS stains revealed findings compatible with the diagnosis of a pheomycotic cyst, and the appropriate cultures confirmed this. This represents an unusual opportunistic infection in an immunosuppressed host. As more patients are managed with immunosuppressive drugs, this diagnosis will need to be considered much more frequently if treatment is to be effective.

Diagnosis, Differential↗

A modified tongue-lip adhesion for Pierre Robin anomalad.

A modified tongue-lip adhesion for Pierre Robin anomalad, based on the work of Douglas (1946), Routledge (1960) and Randall (1977) is described. Modifications include placement of the incision and stripping of the geniglossus muscles from the mandible. Conservative non-operative management is successful for most patients, but an adequate surgical adhesion avoids tracheostomy when more active treatment is needed.

Humans↗

Nasal obstruction as a complication of pharyngeal flap surgery.

In a series of 85 patients who had pharyngeal flap surgery at Indiana University Medical Center, We found an unusually high incidence of hyponasality with total or near total nasal obstruction. The nasal obstruction was often occult, detected only after careful questioning and examination. Nasal obstruction was associated with peri-operative infection or micrognathia as in the Pierre Robin Anomalad. Flap division or port revision yielded a significant relief of the nasal obstruction and achievement of normal nasal balance.

Adolescent↗

Familial velopharyngeal incompetence caused by myasthenia gravis.

This report describes 2 cases of familial myasthenia gravis presenting as velopharyngeal incompetence. The diagnosis was made only after pharyngoplasty had been done. Symptoms suggesting possible myasthenia gravis are seen in speech therapy and cleft palate clinics, and often labeled "palatal insufficiency" without a more specific diagnosis. In spite of the fact that myasthenia gravis is usually mentioned in the differential diagnosis of velopharyngeal incompetence, it is rarely ruled out by specific studies. We urge that myasthenia gravis be ruled out by definitive tests when the cause of neuromuscular dysfunction cannot be definitely established.

Adult↗

Management of the silicone-injected breast.

Our experiences with 28 patients who had a history of liquid "silicone" injections of the breasts has led us to recognize a typical clinical picture. Several years after the injections, the patient may develop hard, lumpy, tender breasts which make the detection of breast cancer impossible. Mammograms are generally inconclusive. Despite the reluctance of the patients and surgeons, the conservative approach is a subcutaneous mastectomy with possible subsequent reconstruction.

Breast↗

Scar prognosis.

Scar prognosis is a matter of great natural interest to patients. It is important to realize that the nature of the injury is the most important consideration in the final result. The orientation of the wound in relation to the normal lines of skin tension, its location and pattern, and peculiarities of the individual are all determining factors in the final appearance. Good surgical technique is quite well understood, if not always practiced. The final assessment must always await full maturation of the scar. When discussing either the prognosis or the evaluation of a scar, it must be remembered that the view of the patient is influenced by many subjective factors and will not always coincide with the objective evidence. A knowledge of the factors in scar prognosis is invaluable in establishing and maintaining the rapport and confidence of patients.

Cicatrix↗

Peripheral intravenous infiltration necrosis.

Peripheral extravasation of intravenous solutions containing calcium salts and/or 10% dextrose has caused significant local tissue necrosis in 8 patients, including 6 infants. These incidents prolonged hospitalization and in 5 cases caused severe disfigurement or imperiled limb function. Treatment followed established principles of debridement, early skin grafting and secondary reconstruction as needed. While intravenous alimentation or the administration of calcium salts if often indicated by the clinical situation, the physician administering these drugs must realize that extravasation may cause serious sequelae.

Adult↗

Corneal changes associated with hypertrophic scars of the eyelids.

Acquired astigmatism secondary to scar contracture of the eyelids was diagnosed in a burned patient, with decrease in visual acuity to 20/400. This was associated with a persistent mosaic pattern of the cornea when stained with fluorescein. Visual acuity returned to normal and the mosaic pattern disappeared after treatment of the scars. This unusual problem should be looked for in patients with scarred eyelids to decrease morbidity and prevent possible permanent corneal changes.

Adult↗