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R W Pain

Publications and source records attributed to R W Pain.

At least 19 recordsLinked to original sources

The anion gap.

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Aged

Thyroid disease in a psychogeriatric population.

Over a six-year period, routine biochemical screening for thyroid disease was carried out on 662 patients aged 65 years and older, admitted to the psychogeriatric unit of a major psychiatric hospital. Hypothyroid values were found in 1.2% of the population (8 patients). Hyperthyroid values occurred in 0.76% (5 patients). The thyroid abnormality was considered a significant factor in the psychiatric presentation of only two patients and in both the thyroid disease was clinically apparent. Practical benefits obtained were so disappointing that they did not justify the practice of routine screening in this type of patient.

Age Factors

Body fluid compartments.

The terms mole, molality, molarity, osmole, osmolality, osmolarity, osmolar gap and anion gap are defined and their clinical usefulness indicated. The following body fluid compartments are described: total body water (TBW), extracellular fluid (ECF), intracellular fluid (ICF), transcellular fluid TCF), plasma volume, red cell volume and interstitial fluid volume. Isotope-dilution techniques are briefly discussed and representative normal values for the various compartments according to sex and age are indicated. The physiological mechanisms that maintain the distinctive ionic compositions of the various fluid spaces are briefly outlined. New concepts of the function of the gel matrix and of the lymph drainage of the interstitium are presented. Opposing models to the sodium-potassium membrane pump are briefly described.

Body Fluid Compartments