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Biomedical subjects

R W Olson

Publications and source records attributed to R W Olson.

27 records · Page 2Linked to original sources
PubMed1979

Evaluation of a program of bed rest in the treatment of chronic hypertension in pregnancy.

Sixty-six patients with chronic hypertension were cared for during a total of 72 pregnancies. Patients were treated at home primarily by greater than or equal to 4 hours of bed rest daily in the left recumbent position. Only patients whose diastolic blood pressures remained greater than 110 mmHg were treated with hydralazine (Apresoline, Ciba). With this plan of treatment there were only 3 perinatal deaths for an uncorrected perinatal mortality of 4.1% (1.4% corrected). Twenty-nine percent of the patients had babies that were small for gestational age, 13.8% had positive oxytocin challenge tests, and 36.8% developed superimposed preeclampsia. When compared with the outcome of previous pregnancies, the program of bed rest lowered perinatal mortality from 16.8 to 8.8%. Thus, it is suggested that bed rest together with the avoidance of diuretics and the judicious use of hydralazine results in the most favorable fetal outcome.

Bed Rest↗
PubMed1978

Screening for fetal and neonatal risk in the postdate pregnancy.

One hundred four postdate pregnancies were managed according to a well-defined protocol calling for weekly oxytocin challenge tests and urinary estriols three times per week. Although the perinatal mortality rate in these patients was not increased there was a significant increase in the incidence of neonatal morbidity and complications. The clinical syndrome of dysmaturity was seen in 20 per cent of the neonates. When meconium was present in the amniotic fluid the incidence of neonatal and fetal complications was higher. The cesarean section rate was twice the normal rate, with nonprogression of labor being the commonest indication. It is recommended that: (1) pregnancies carried beyond 42 weeks do not require termination simply because they are post dates; (2) all postdate patients should be monitored during labor; (3) trained personnel to initiate neonatal resuscitation should be present at each postdate delivery.

Amniocentesis↗
PubMed1975

Measles pneumonia. Bacterial suprainfection as a complicating factor.

During a 3 1/2-month period, 32 previously healthy young men were first seen typical prodromal symptoms and signs of measles. On admission or within 48 hours of admission, 16 patients (50%) manifested physical signs and roentgenographic evidence of pneumonia. Of these 16 patients, ten (63%) were found to have bacterial suprainfection or colonization confirmed by culture of transtracheal aspirates. From six of these ten patients, Neisseria meningitidis serogroup Y was isolated as the sole organism responsible for suprainfection. In the other patients, Haemophilus species, Neisseria species (not N gonorrheae or N meningitidis), Streptococcus pneumoniae, and beta-hemolytic Streptococcus (not group A or D were isolated alone or in combination. The data suggest that bacterial supra-infection associated with measles pneumonia is not unusual in adults and N meningitidis serogroup Y is a potential pathogen of the lower respiratory tract.

Adolescent↗