Functional expression of the Na,K-ATPase using baculovirus.
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Animals↗
Biomedical subjects
R W Mercer
Publications and source records attributed to R W Mercer.
Molecular cloning and characterization of alpha-subunit isoforms of the Na,K-ATPase.
The identification of the different alpha-subunit isoforms of the Na,K-ATPase has added an unexpected complexity to the understanding of the function and regulation of this important transport protein. Our results indicate that the alpha, alpha(+) and alpha III isoform mRNAs have distinct, but partially overlapping, distributions in brain and peripheral tissues. Also, characterization of mRNA distribution in fetal tissues suggests that the Na,K-ATPase alpha-subunit isoforms are regulated during development and differentiation. The developmental regulation and strikingly different tissue specificities of the three alpha-subunit isoforms suggests that the different Na,K-ATPase alpha-subunits may be adapted to perform different roles in maintaining sodium and potassium homeostasis.
Animals↗
A technique for finishing and polishing denture bases.
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Denture Bases↗