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Biomedical subjects

R W Haley

Publications and source records attributed to R W Haley.

87 records · Page 5Linked to original sources

The emergence of infection surveillance and control programs in US hospitals: an assessment, 1976.

To assess the current state of hospitals' infection surveillance and control programs (ISCPs) nationwide and to provide a sampling frame for selecting hospitals for later phases of the SENIC Project, the authors mailed a screening questionnaire in March, 1976, to virtually all US hospitals; 86% of those in the SENIC target universe responded. Of these, 64% (2299) reported that their ISCPs were being supervised by a physician or a microbiologist with special interest in infection control, and 42% had an infection control nurse (ICN), or equivalent, working at least half time. In contrast to the supervisors, most of the ICN's had recieved special training in hospital infection epidemiology and spent the majority of their time doing surveillance. Almost all hospitals (87%) had practiced some form of infection surveillance. Almost all hospitals (87%) had practiced some form of infection surveillance, with half reporting very active programs. Larger hospitals with ISCP staff tended to use active clinical casefinding methods, while smaller hospitals tended to use passive techniques. Most hospitals (76%) were collecting relatively large numbers of environmental cultures routinely, although a growing number (about 25%) had reduced or discontinued this practice. Routine culturing was more often performed in hospitals employing passive surveillance methods. Although the adoption of selected infection control policies and practices has varied widely, chronological data indicate that a major infection control movement has emerged since 1970.

Cross Infection↗

The infection control nurse in US hospitals, 1976-1977. Characteristics of the position and its occupant.

Within the past decade, the infection control nurse (ICN) has become an important element in organized infection surveillance and control programs. Before 1970, only a few hospitals (6%) had an ICN, but, by 1977, over 80% had hired at least one ICN, the majority of those hospitals having done so since 1973. To determine the characteristics of the position and its occupant, the authors analyzed data from interviews with a representative sample of ICNs from 347 hospitals nationwide, conducted in 1976-1977 as part of Phase II of the Study on the Efficacy of Nosocomial Infection Control (SENIC Project), the Hospital Interview Survey. Results varied most widely by hospital size. The ICN in the smaller hospitals (less than or equal to 300 beds) typically worked only part time in infection control, spending the rest of her or his time as a nursing supervisor. The ICN in the larger hospitals (greater than 300 beds) generally worked full time but actually worked less time in relation to the number of beds; she or he also had completed a higher level of nursing education and had attended more infection control courses. The ICN was typically a woman in the young or middle age group who had worked in her current hospital six years altogether--two of them in infection control--and was receiving a supervisor's salary. Most ICNs were under the Nursing Service Department but generally looked to the physician in the infection control program for advice or supervision.

Adult↗

Nosocomial bacteriuria: a prospective study of case clustering and antimicrobial resistance.

To investigate the role of cross-infection in nonepidemic nosocomial bacteriuria in a large, university-affiliated hospital, we identified in adult patients admitted over an 11-week period all cases caused by organisms of the same genus, species, and antimicrobial susceptibility and clustered by date of onset and hospital ward. Further laboratory studies were conducted to verify clustering. Among the 3452 patients studied, 194 cases of nosocomial bacteriuria were identified; 49 appeared clustered by epidemiologic evidence. Additional laboratory tests verified clustering in 30 cases (15.5%). We found that 90% of clustered and 76% of nonclustered cases had had previous urinary catheterization; Pseudomonas aeruginosa, Serratia marcescens, and Citrobacter freundii often caused clustered infection while Escherichia coli predominated in nonclustered cases; and resistance to gentamicin, sulfathiazole, and carbenicillin was significantly greater for pathogens from clustered cases than for nonclustered ones. This increased resistance emphasizes the need to prevent cross-infection, even in the absence of epidemics.

Anti-Bacterial Agents↗

Reproducibility of interpretation of the test for antibody-coated bacteria in urinary sediment.

The direct immunofluorescence technique for detecting antibody-coated bacteria in urinary sediment is felt to be useful in distinguishing infection of the kidney from infection of the bladder. An independent, blind multiple-reading system was used to measure interobserver variability in the evaluation of slides of urinary sediments for antibody-coated bacteria. Three independent observers agreed unanimously on first reading in 88% of 253 specimens. When compared with the majority opinion, the sensitivity and specificity of an individual reading were 91 and 95%, respectively.

Bacteria↗

The "hospital epidemiologist" in U.S. hospitals, 1976-1977: a description of the head of the infection surveillance and control program. Report from the SENIC project.

As part of the first two phases of the SENIC Project (Study on the Efficacy of Nosocomial Infection Control), information was collected from the heads of the infection surveillance and control programs (ISCPs) in U.S. hospitals. The data were analyzed to describe these respondents and to determine whether differences among them were related to their areas of professional training or to characteristics of the hospitals where they were located. The findings indicate that the ISCP heads constitute a very heterogeneous group, with substantial differences in age, professional training (40% are pathologists), characteristics of their medical practices, memberships in professional organizations related to infection control, time spent in ISCP activities, approach to epidemiologic problems, and opinions on the preventability of nosocomial infections and the seriousness of infection problems in their hospitals. These differences are related strongly to the ISCP heads' professional training, size of hospital, and, to a lesser extent, medical school affiliation, but there is little evidence that the differences are related to regional or urban-rural location or type of ownership of the hospitals. The average ISCP head estimates that about half of all nosocomial infections are preventable, but these estimates vary inversely with tenure in the position and the tendency to approach a clinical problem epidemiologically.

Administrative Personnel↗

High cost nosocomial infections.

The average charge per patient due to nosocomial infection for 215 nosocomial infections in 183 study patients was $693. These cost, however, were concentrated in very few patients; 5% of patients accounted for nearly one-third of total charges. The 10% of patients with highest nosocomial infection cost were patients on Medical or Surgical services; these services were utilized in 71% of patients with nosocomial infection and accounted for 86% of the attributable charges. Among the 22 most costly infections, 17 occurred in surgical wounds and lower respiratory tract. Although these sites accounted for 46% of the infections, they resulted in 77% of the total nosocomial infection charges. Patients with a primary diagnosis of injury had particularly costly infections. Combined analysis of these variables revealed two groups for whom nosocomial infections were especially costly: surgical patients who acquired wound infections after injuries, and medical patients with lower respiratory infections.

Cost Allocation↗

The usefulness of a conceptual model in the study of the efficacy of infection surveillance and control programs.

To identify characteristics and activities that should be studied in evaluating the efficacy of infection surveillance and control programs (ISCPs), we developed a conceptual model for use in designing the data collection forms and analytic strategies for the Study on the Efficacy of Nosocomial Infection Control. The model emphasizes the prevention of infection by improving patient-care practices. From information collected during the hospital interview survey, we found substantial gaps between what should be practiced and what is; moreover, hospitals varied substantially in their approaches to improving these practices. The model and these diverse findings suggest ways in which hospitals can improve their ISCPs.

Cross Infection↗

Nosocomial infection control: role of the hospital administrator.

The role of the hospital administrator regarding the implementation and maintenance of programs for the prevention and control of nosocomial infections in U.S. hospitals is discussed. Data obtained in the Study on the Efficacy of Nosocomial Infection Control provide the basis for describing the backgrounds, demographic characteristics, functions, and potential functions of this official as s/he interacts with members of the infection control committee and other hospital staff. The infection control program of a hospital must have the support of the hospital administrator to be effective.

Cross Infection↗

Polymicrobial bacteremia associated with lipid emulsion in a neonatal intensive care unit.

Polymicrobial bacteremia developed in 5 of 20 infants in a neonatal intensive care unit during a 48-hour period; 2 infants died. Klebsiella pneumoniae serotypes 21 and 24 and Enterobacter cloacae were isolated from four infants, and K. pneumoniae serotype 24 and E. cloacae were isolated from the other infant. Case-control studies revealed an association between receipt of lipid emulsion on one day and the subsequent development of bacteremia (P = 0.0005). Epidemiologic evidence suggested that extrinsic contamination of the lipid emulsion bottles had occurred when the hands of a nurse became transiently colonized with these organisms while she was caring for an infant colonized with K. pneumoniae and E. cloacae. Repeated entry of the lipid emulsion bottle, which was used as a multidose medication, probably resulted in contamination. No further cases occurred after lipid emulsion administration practices were changed. We recommend that, except in a pharmacy where conditions for unit dose distribution exist, lipid emulsion should not be used as a multiple dose medication because repeated entry of the bottles increases the risk of contamination. Furthermore lipid emulsion from one container should be administered to only one infant.

Cross Infection↗