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Biomedical subjects

R W Emmons

Publications and source records attributed to R W Emmons.

At least 37 records · Page 2Linked to original sources
PubMed1980

Fatal pulmonary psittacosis and aspergillosis. Case report of dual infection.

A 59-year-old man in previously good health had acute, progressive bronchopneumonia and died after a three-week course of illness, despite treatment with various antibiotics. Serologic, microbiologic, and histologic findings indicated infection with both Chlamydia psittaci and Aspergillus fumigatus. Disseminated, invasive aspergillosis sometimes is a complication of chronic respiratory disease, malignancy, or other deficiency of host defenses, but to our knowledge, this is the first report of psittacosis as a coincidental, probably predisposing disease.

Aspergillosis↗
PubMed1979

Correlation of Culex tarsalis population indices with the incidence of St. Louis encephalitis and western equine encephalomyelitis in California.

Mosquito population indices from California for the period 1953-1973 were analyzed to determine their association with activity of St. Louis encephalitis (SLE) and western equine encephalomyelitis (WEE) viruses. Culex tarsalis female populations, as measured by New Jersey light trap indices (LTI), correlated positively with the incidence rates of encephalitis in humans, and were a reliable means of forecasting the years of highest incidence. The critical level of C. tarsalis in urban areas below which no human cases of SLE and WEE were detected was an LTI of 0.1. Critical urban levels of C. tarsalis associated with significant human SLE or WEE incidence ranged between LTIs of 6.4 (for rural mosquito abatement districts [MADs] with large resident human populations). Peaks in annual incidence of SLE and WEE in humans occurred during years when seasonal average C. tarsalis female populations in urban areas reached a LTI of 21. Peaks in weekly incidence of SLE and WEE were associated, respectively, with weekly LTIs of 21 and 81 in urban traps. Isolation rates of SLE virus from mosquito pools and transmission of the virus to enzootic hosts were highest when urban LTIs were between 10 and 19.9 and between 5 and 9.9, respectively. The WEE viral isolations and enzootic transmission rates were highest when LTIs in urban areas were 1-4.9.

Animals↗
PubMed1978

Rabies vaccine virus infection in three dogs.

Ascending paralysis developed in 3 dogs, 12 to 14 days following inoculation with a modified live virus, chicken embryo origin, low egg passage, Flury strain rabies vaccine. The paralysis began in the inoculated limb but rapidly involved both hindlimbs. Partial paresis of the forelimbs was seen several days following the hindlimb paralysis in all 3 dogs, and in 1 of these dogs the infection ascended rapidly to the brain as well. Two of the dogs recovered within 1 and 2 months, respectively, but the 3rd dog died within 5 days of the onset of paralytic signs. The fatal case was complicated by naturally acquired coincidental distemper. Serologic studies in 2 dogs and virus isolation from the 3rd dog indicated that rabies virus was the cause of the paralysis in 2 of the dogs and contributed to the disease syndrome in the 3rd dog. Virus could not be isolated from the saliva of CSF of the 2 surviving dogs. The virus isolated in the fatal case appeared to have some of the characteristics of the vaccine virus, as determined by its behavior in mice, cell culture, and embryonating chicken eggs and by its failure to produce Negri bodies in the brain of the infected dog.

Animals↗
PubMed1978

The development of Colorado tick fever virus within cells of the haemopoietic system.

Electron microscopic examination of haemopoietic liver tissue from mice infected in utero or when newborn showed inclusions of Colorado tick fever virus within erythroblasts, reticulocytes and erythrocytes. Inclusions were also seen within erythroblastoid cells undergoing mitosis. Other evidence of virus replication within erythropoietic cells was the presence of intracytoplasmic and intranuclear fibres, which have been shown to be associated with Colorado tick fever virus replication. The findings reported here support the hypothesis that virus replication within infected erythropoietic cells occurs concurrently with differentiation of the infected cell, resulting in the presence of virions within erythrocytes.

Animals↗
PubMed1978

Human rabies.

Explore the source record for details and available documents.

Adolescent↗
PubMed1976

Measles in adults. An unforeseen consequence of immunization?

An outbreak of measles occurred in California in the first half of 1975, especially in the San Francisco Bay area. Of four adult patients with complicated cases, two were receiving immunosuppressive chemotherapy, and both died from a giant-cell pneumonia. The clinical presentation in such cases may be atypical, and special viral isolation and immunofluorescent techniques may be diagnostically helpful. A significant (P less than .0005) trend toward the occurrence of measles in adolescents was observed in this epidemic, which may also occur in future epidemics elsewhere. With wide spread but incomplete immunization, it is possible for the nonimmunized to reach adulthood without acquiring natural infection. As a result, internists as well as pediatricians will have to consider the possibility of measles and be aware of its serious potential in the immunosuppressed patient.

Adolescent↗
PubMed1976

Continuing search for the etiology of cat scratch disease.

Fifty cat scratch disease patients were tested for antibodies against candidate etiological agents, with inconclusive results. Future research should emphasize new viral isolation methods to discover the elusive agent.

Antibodies, Bacterial↗
PubMed1976

Tularemia in a mule deer.

A case of tularemia was confirmed in a 51-year-old man who acquired the disease from a mule deer, Odocoileus hemionus. Francisella tularensis was isolated from bone marrow of the deer carcass.

Animals↗
PubMed1976

Rapid diagnosis of mumps virus infections by immunofluorescence methods.

Mumps and its complications, particularly meningoencephalitis, is an important disease problem, and more rapid diagnostic methods are desirable. A study was made of immunofluorescence methods for the early detection of mumps virus isolated in cell cultures, or adsorbed directly from clinical specimens onto guinea pig erythrocytes. A specific diagnosis could be made in hours to 2 or 3 days utilizing immunofluorescence methods, in contrast to about 6 days by standard methods. Details of the direct immunofluorescence methods are presented, to encourage wider application in clinical virology laboratories.

Animals↗
PubMed1975

Recovery from encephalomyelitis caused by Herpesvirus simiae. Report of a case.

A 29-year-old monkey handler developed an acute encephalomyelitis with neuromuscular dysfunction that progressed to respiratory arrest on the 18th day of illness. Thereafter, with supportive care, the patient's condition improved steadily. The titer of neutralizing antibodies to H simiae rose from 1:4 (eighth day of illness) to 1:512 (47th day of illness). Apparently the fifth known survivor of H simiae (herpesvirus B) encephalomyelitis, this patient is also remarkable because of virtually complete recovery, apparently the second documented instance of a good outcome.

Adult↗