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Biomedical subjects

R W Briles

Publications and source records attributed to R W Briles.

25 records · Page 2Linked to original sources
PubMed1986

Resistance to natural and controlled exposures to Eimeria tenella: genetic variation and alloantigen systems.

Chickens from lines selected for high (HA) and low (LA) antibody response to sheep erythrocyte antigens were used to study relationships between blood group systems and resistance to Eimeria tenella. Results of natural and controlled exposures to E. tenella showed Line HA chickens to be more resistant than those from Line LA. Differences in resistance to E. tenella were found among alleles for the I blood group system with degree of resistance depending on the background genome.

Animals↗
PubMed1984

A study of linkage relationships of blood group P with naked neck, silkie feathering, and recessive white in chicken.

Linkage relationships of blood group P (Ea-P), naked neck (Na), silkie feathering (h), and recessive white plumage (c) were studied to attempt to clarify the h-Na-Ea-P region of linkage group III of the chicken. The Na-Ea-P linkage values obtained in this test agreed with previous reports, and pooled data were used to recalculate a map distance of 27.9 +/- 2.3 map units between these two loci. A significant chi square for linkage was calculated between Na and c; however, because of the relatively low numbers of progeny tested, the high linkage value calculated, and the absence of detectable linkage between c and the other marker genes, this was probably a chance deviation. All other linkage relationships appeared negative, supporting the current suggested linear order of these loci as h-Na-Ea-P with c not being in this chromosomal region.

Animals↗
PubMed1984

Allelic frequencies in eight alloantigen systems of chickens selected for high and low antibody response to sheep red blood cells.

Parents and offspring from lines of chickens selected for high (HA) and low (LA) antibody response to sheep red blood cell antigen(s) were blood typed for systems A, B, C, D, E, H, I, and L. All birds were homozygous for allele L2, and allelic frequencies for the I system were essentially identical in both lines. In contrast, allelic frequencies of the other blood group systems differed rather markedly between the HA and LA lines.

Alleles↗
PubMed1983

Resistance to a malignant lymphoma in chickens is mapped to subregion of major histocompatibility (B) complex.

A genetic recombinant within the major histocompatibility (B) complex of the chicken has revealed the chromosomal subregion effecting resistance to Marek's disease--a malignant lymphoma induced by a herpesvirus. The recombinant, BF21-G19, occurred spontaneously among the progeny of a male heterozygous for resistant BF21-G21 and susceptible BF19-G19 haplotypes. Exposure to Marek's disease of families segregating for the recombinant showed that this new F-G arrangement conferred a level of resistance equivalent to that of the resistant parental haplotype. Thus, a gene, or genes, within or closely linked to the B-F region of the B complex appears to be responsible for the observed resistance to Marek's disease.

Animals↗