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Biomedical subjects

R W Beard

Publications and source records attributed to R W Beard.

At least 199 records · Page 11Linked to original sources

Blood glucose and insulin relationships in the human mother and fetus before onset of labour.

The effects of a maternal intravenous glucose load on the fetal plasma levels of glucose and insulin have been studied in 11 patients before the onset of labour. Within five minutes the fetal plasma glucose concentration rose significantly, indicating a rapid transfer of glucose across the placenta. Following this, the rate of fall in fetal plasma glucose closely reflected that in the mother.Serial fetal insulin estimations carried out in 8 of the 11 subjects following maternal glucose showed an early rise in fetal insulin in four and a delayed rise in one; in the remaining three there was no definite change.It is concluded that the blood glucose level of the fetus is controlled by that of the mother, but that the fetal pancreas at term may respond to hyperglycaemia by the secretion of insulin.

Blood Glucose↗

Foetal blood sampling. Practical approach to management of foetal distress.

The practical application of foetal blood sampling in the routine management of patients in labour has been reviewed in a six-month survey, during which time 1,668 patients were delivered at Queen Charlotte's Hospital.Foetal acidaemia (pH 7.25 or less) occurred in 45 of the 295 patients who showed clinical signs of foetal distress. Foetal tachycardia was the presenting sign in 33 of these 45 patients, underlining the importance of this physical sign. Foetal acidaemia in association with clinical foetal distress occurred twice as often in patients who had complications of pregnancy and who were therefore regarded as obstetrically "at risk" as it did in patients who were obstetrically "normal" No cases of acidaemia were detected in any of the foetal blood samples performed routinely on "at-risk" patients in the absence of clinical foetal distress.

Acidosis↗

Foetal diagnosis.

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Amniotic Fluid↗