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Biomedical subjects

R W Barnes

Publications and source records attributed to R W Barnes.

At least 127 records · Page 7Linked to original sources
PubMed1982

Fibrodysplasia of the popliteal arteries.

Fibrodysplasia is a generalized arterial dysplasia of unknown etiology. We report a case involving both popliteal arteries. The patient presented with microemboli of the toes of both feet originating in the dysplastic popliteal arteries. The clinical significance of popliteal artery fibrodysplasia is briefly discussed.

Aged↗
PubMed1982

Infant formula label review.

The FDA review of infant formula labeling was conducted by a multi-disciplinary team composed of physicians, scientists, and experts in regulations and labeling. The review followed 2 tracks: the development of a general position of what would be necessary if we started with a blank label; and the purchase of many formulas and a critical review of information on the labels. An important part of the review was determining what information was available in the literature and using this information in assessing current practices and the effectiveness of present labeling. The review was divided into several major topics: introduction, definitions, historical perspectives, current regulatory situation, effectiveness of labeling, label review, other issues, and departmental initiatives. The labels review included product attributes, shelf life, retail and home storage instructions, and consumer preparation and use.

Food Labeling↗
PubMed1981

Prediction of amputation wound healing. Roles of Doppler ultrasound and digit photoplethysmography.

Segmental limb blood pressures (BPs) measured by Doppler ultrasound and digit photoplethysmography were used to define hemodynamic correlates of wound healing in 122 lower-extremity amputations for ischemia. Healing of digit or transmetatarsal amputations were influenced by the presence of diabetes and correlated better with digit pulsation and BP than with ankle pressure. Healing of below-knee amputation did not correlate with segmental limb BPs. In the absence of an absolute threshold to predict wound healing or failure, caution is urged in using hemodynamic indices to select the level of amputation of arterial insufficiency.

Aged↗
PubMed1981

Audible interpretation of carotid Doppler signals. An improved technique to define carotid artery disease.

Direct interrogation of the common, internal, and external carotid arteries with a bidirectional Doppler detector was performed on 199 vessels in 101 patients. Audible interpretations of normal, disturbed (stenotic), or absent (occluded) flow signals were made by vascular technologists and the results were compared with independently assessed carotid arteriograms. The sensitivity in detecting severe (greater than or equal to 50%) stenosis or occlusion was 9.2%, with correct differentiation of these two conditions in 84% of vessels. Nonobstructive (less than 50%) stenoses were detected in 30% of cases. The specificity in identifying normal carotid arteries was 91%. The predictive values of normal, abnormal, and absent flow signals were 95%, 90%, and 90%, respectively. Direct carotid Doppler signal analysis is more accurate than indirect periorbital Doppler screening in defining carotid stenosis or occlusion.

Adult↗
PubMed1981

Incontinence following transurethral resection of the bladder neck in the female.

Incontinence is an unwelcome complication of transurethral resection (TUR) of the bladder neck in the female. A computerised analysis of 238 procedures performed during the period 1940 to 1972 was carried out to assess the morbidity due to this complication and to evaluate possible predisposing factors. Initially 15.2% of patients were incontinent but 70% of these soon became continent without further treatment. The remaining 4.7% were treated by surgical or other measures. The incidence of incontinence was unrelated to the amount of tissue removed or to the number of operations, but was significantly lower when the operation was done for polypi of the bladder neck and significantly higher in patients with a cystocele or urethrocele. It seems possible to reduce the incidence of incontinence by careful selection of cases.

Adolescent↗
PubMed1981

Office Doppler techniques in vascular disease.

The Doppler ultrasonic velocity detector is the least expensive and most versatile instrument used to screen patients for peripheral arterial, cerebrovascular, and venous disease. The Doppler detector provides qualitative and quantitative estimates of arterial and venous flow velocity and segmental arterial pressure measurements. The device can become as clinically useful as the stethoscope to screen patients for vascular disorders. New audiovisual instructional aids may make this technique a routine complement to the clinician's diagnostic resources.

Arterial Occlusive Diseases↗
PubMed1981

The natural history of asymptomatic carotid disease in patients undergoing cardiovascular surgery.

Prospective screening of 449 patients undergoing coronary or peripheral arterial revascularization detected asymptomatic cervical bruits in 44 patients (9.8%) and carotid obstruction by Doppler ultrasound in 63 individuals (14.0%). There was poor correlation between cervical bruit and carotid obstsruction. No patient underwent prophylactic casrotid endarterectomy. Three patients had transient ischemic attacks (TIAs), and five had nonfatal strokes perioperatively, only one of which was in the territory appropriate to carotid obstruction. Of 72 surviving patients with asymptomatic carotid disease, 10 (13.9%) had TIAs and one (1.4%) died of stroke during a 2-year follow-up, during which time only two (0.8%) of 254 patients without carotid disease reported symptoms of TIAs. Patients with asymptomatic carotid disease had a significantly higher incidence of perioperative and late deaths (10.6% and 9.2%, respectively), usually of myocardial infarction, as compared to patients without carotid disease (0.3% and 0.8%, respectively, P less than 0.001). Asymp-tomatic carotid disease, although correlating poorly with perioperative stroke in patients undergoing cardiovascular operations, identifies patients at risk of late neurologic events and peroperative or late deaths from myocardial infarction. We do not recommend prophylactic carotid endarterectomy but favor operative intervention if patients develop TIAs during a period of careful follow-up .

Adult↗
PubMed1980

Hemodynamics for the vascular surgeon.

Basic principles of fluid dynamics and material properties underlie many facets of the diagnosis, treatment, and natural history of vascular disease. I review the concepts of total fluid energy and both viscous and inertial energy losses with reference to arterial occlusive disease. I contrast the vascular wall properties of arteries and veins and discuss the relevance of mechanical principles to arterial aneurysm. I review the pathophysiologic features of small and large arteriovenous fistula. Finally, I discuss the altered dynamics associated with venous obstruction and valvular insufficiency in light of recent noninvasive diagnostic techniques that provide simple rapid assessment of venous pathophysiologic features.

Aneurysm↗
PubMed1980

Thoracic outlet arterial compression: prevalence in normal persons.

The prevalence of thoracic outlet compression of the subclavian or axillary artery was determined in both upper extremities of 130 normal individuals. Photoplethysmographic (PPG) recordings were made simultaneously in each index finger during performance of Adson, Costoclavicular, and hyperabduction maneuvers. Significant arterial obstruction resulted from one or more of these maneuvers in 78 subjects (60%) and was bilateral in 43 individuals (33%). Thoracic outlet arterial compression is common in normal persons and thus has little diagnostic value in symptomatic patients.

Adolescent↗