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Biomedical subjects

R Vasiu

Publications and source records attributed to R Vasiu.

At least 19 recordsLinked to original sources
PubMedDate not supplied

Automated estimation of nuclear volume in brain tumors.

The comparative study of the percentage nuclear area in brain tumors by the point-counting technique and digital analysis showed a good correlation between the results obtained. The investigation suggests the possibility of using the volume corrected mitotic index to tumors with uniformly distributed cells.

Astrocytoma↗
PubMedDate not supplied

Composite endocrine cell, typical adenocarcinoma and signet ring carcinoma of the gallbladder.

The authors report a case of composite tumor of the gallbladder which exhibited features of both adenocarcinoma (with typical areas, signet ring cells and clear cells) and endocrine cell carcinoma. The histological picture suggests the origin of both components in a common primitive cell with the capacity to differentiate to different types of metaplastic epithelium and supports the hypothesis of a sequence metaplasia--dysplasia--carcinoma.

Adenocarcinoma↗
PubMedDate not supplied

Gastric Burkitt's lymphoma. Case report and review of the literature.

A case of gastric Burkitt's lymphoma with pancreatic infiltration in a 15-year-old boy is reported. Local lymph nodes were not involved. Review of the literature disclosed that the reported cases of Burkitt's lymphoma were localized in the intestine. The origin, evolution and prognosis of gastrointestinal lymphoma are briefly discussed.

Adolescent↗
PubMedDate not supplied

DNA nuclear content of apocrine cells in fibrocystic mastopathy and breast cancer.

The DNA nuclear content of apocrine cells was studied in 5 cases of fibrocystic disease, 3 cases of invasive duct carcinoma and 3 cases of invasive lobular carcinoma. Both diploid and aneuploid values were found in each group. The possible significance of apocrine change in breast lesions is discussed.

Apocrine Glands↗
PubMedDate not supplied

Morphometric grading of laryngeal squamous cell carcinomas.

The authors have used the point counting method for the morphometric assessment of the histological aspect of laryngeal carcinoma. The results suggest that subjective histopathological grading tends to overestimate the tumor grade. The implications of these data for the prediction of prognosis and selection of therapy are briefly discussed.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Cytophotometric study of DNA content of cells in type III cervical smears.

Cytophotometric study of suspicious (group III of the Papanicolaou's classification) smears shows the heterogeneity of this group, which includes cases with diploid--tetraploid DNA modes, cases with a wide distribution of DNA values and aneuploid cases. The significance of these findings in relation with the biological properties of cells is briefly discussed.

Cervix Uteri↗
PubMedDate not supplied

Relationship between structural and ionic changes in cardiosclerosis.

The parallelism between hypoxic changes in the myocardium revealed by Lie's technique and by fluorescence microscopy and the ionic changes (Na+, K+, Ca2+) was studied in 51 autopsy cases. The Lie technique was positive in 52.6 per cent of the cases of cardiosclerosis with myocardial infarction and in 15 per cent of the cases of cardiosclerosis without infarction, while fluorescent areas were found in all cases of infarction and in 35 per cent of cardiosclerosis cases without infarction. Na+ and K+ were decreased and Ca2+ ions were increased in both ventricles and in both sexes, both in infarctions and in cardiosclerosis cases without infarction. Ionic changes are more probably related to the intensity of cardiosclerosis rather than to age or sex.

Adult↗
PubMedDate not supplied

Value of quantitative cytologic studies in the grading of papillary tumors of human urinary bladder.

Mitotic indices and nuclear volumes were determined in 10 papillomas, 20 grade I, 20 grade II and 20 grade III papillary carcinomas of the urinary bladder. The mean mitotic indices were 1.22% in papillomas, 2.77% in grade I carcinomas, 8.2% in grade II carcinomas and 15.25% in grade III carcinomas. The nuclear volumes showed a gradual shift to larger values paralleling the histological degree. It is suggested that these objective parameters might be especially useful for the cytological assessment of exfoliated tumor cells.

Carcinoma, Papillary↗
PubMedDate not supplied

Frequency of mortality due to cancer in the last 110 years (1870-1979) in the department of pathology of Cluj-Napoca.

Records of 36,775 autopsies performed between 1870 and 1979 in the Department of Morphopathology, Cluj-Napoca, were re-studied. 10.82 per cent of deaths were due to cancer, whose incidence increased during the last 50 years. Cancer is more often seen in males and its highest incidence was noted between 50 and 70 years of age. Gastric and lung cancers are more frequent in males, while uterine, intestine, stomach and ovarian cancers are the most frequent localizations in females.

Adolescent↗
PubMedDate not supplied

Quantification of Grimelius reaction in neuroendocrine tumors of the lung.

The authors have studied the percent area occupied by the Grimelius-positive cells in lung neuroendocrine tumors. The highest values were noted in typical carcinoid tumors: they decreased progressively in atypical carcinoids, small "oat cell" carcinoma and large cell carcinoma. There was, however, a large dispersion of values, especially in the groups of typical and atypical carcinoid tumors. The possible significance of these data in the diagnosis, evaluation of therapeutical results and prognosis is discussed.

Humans↗