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Biomedical subjects

R Vargues

Publications and source records attributed to R Vargues.

At least 19 recordsLinked to original sources
PubMed1987

[Gastrointestinal infections in children. A strategy for searching pathogenic agents].

From a bacteriological and virological study of 2056 stool samples obtained from 1595 children we have attempted to derive epidemiological arguments leading to an algorithm of coprodiagnosis. We believe that Rotavirus should be systematically searched for at any age, as it is the most frequent pathogen encountered (27% of children with positive detection). If the test is positive, no other test needs to be performed in patients staying less than 4 days in hospital. If the test is negative, or if the child's clinical condition requires prolonged hospitalization, conventional bacteriology must be carried out, including a search for Salmonella, Shigella and Yersinia. The search for Campylobacter should be limited to infections occurring in children under five.

Adolescent↗
PubMed1985

[Development of the sensitivity to antibiotics in strains of Neisseria gonorrhea isolated in Touraine over a 5-year period].

347 Neisseria gonorrhoeae strains isolated in Touraine, France, from December 1978 to March 1984 were tested for susceptibility to seven antibiotics using an agar dilution method. Percentage of strains with a penicillin G MIC = 0.06 micrograms/ml rose from 58% in 78-80 to 69% in 82-84. Consistent amoxicillin MICs were found throughout the survey (MIC 50: 0.125 and MIC 90: 0.5 micrograms/ml). Three penicillinase-producing strains were recovered from patients contaminated outside the study area. For tetracycline, minocycline, chloramphenicol and spectinomycin, variations of MICs 50 and 90 did not exceed one dilution either way. For spiramycin, MICs 50 and 90 fell from 2 and 8 micrograms/ml respectively in 78-80 to 1 and 2 micrograms/ml in 82-84. Our findings show that susceptibility of Gonococci to the main antibiotics used for treating gonococcal infections in our area has not changed significantly over the last five years. Moreover, implantation and diffusion of penicillinase-producing strains has failed to occur.

Anti-Bacterial Agents↗
PubMed1979

[Use of the API 20E system for rapid identification of Enterobacteriaceae (six hours) (author's transl)].

The authors propose a modification of the method of use of the API 20E system permitting more rapid identification of Enterobacteriaceae within six hours (3 hours preculture and 3 hours incubation on an API 20E plate) it was possible to identify correctly 67% of 192 strains studied at species level and 75.5% studied at generic level. One may note four mistakes (2.1%) of which 3 were minor, (species within the same genus). The construction of a base of numerical data adapted to the technic within six hours would no doubt permit us to reduce the percentage undetermined.

Enterobacteriaceae↗
PubMed1978

[Effect of haemolysin of Pseudomonas aeruginosa on Ehrlich ascites tumor cells].

Haemolysin of Pseudomonas aeruginosa exerts toxic effects upon the metabolism of Ehrlich ascitic tumor cells : morphological changes appear readily ; respiration is inhibited more slowly ; the lethal effect determined by intraperitoneal injection of tumor cells is neutralized. Inhibition with human normal sera is complete for the hemolytic action, but incomplete for the cytopathic action.

Animals↗
PubMed1970

A new rapid method for automatic complement-fixation tests.

Several automatic methods have been described for complement-fixation tests. However, each of these methods presents some inconvenience either due to cross contamination or to limited sensitivity. The new method consists basically in separating clearly the fixation stage from the haemolytic stage by using two different sampler plates placed on the same sampler. By this procedure, it becomes possible to obtain a very high sensitivity. The serologist may set the temperature and the duration of the reaction according to the properties of the tests under study. In addition, the sampling rate can be raised to 120 analyses per hour.

Animals↗