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Biomedical subjects

R Urban

Publications and source records attributed to R Urban.

88 records · Page 5Linked to original sources

Study of inhalation toxicity of performic, peracetic and perpropionic acid in mice.

The acute and subacute inhalation toxicity of laboratory performic, peracetic and stabilized aqueous peracetic acid solution. The differences in the toxicity of the studied of the commercial preparation Persteril for mice was studied. Persteril is a 40% peracids were not statistically significant. The histological findings in the lung tissue of intoxicated mice show that the effet of the given peracids is qualitatively the same. Although their toxicity is not very high, in repared inhalation they can induce temporary pathomorphological lesions in the lung parenchyma and have a negative effect on the development of mice in concentrations of about only 70 mg/m3 air. As regards their inhalation toxicity, performic and perpropionic acid have no advantages over peracetic acid for practical use in the air disinfection. The findings show that it is necessary for persons carrying out spatial disinfection with one of the studied peracids to wear an protective mask.

Acetates↗

[Rater-specific variables in judging depressive patients (author's transl)].

Four raters judged their sympathy towards 19 depressed patients and also the intensity of their disease using thermometer-scales. It was exmained whether there was a correlation between the two scores. A rater-specifuc varuabke was fiybd fir eacg if tge fiyr raters. The importance of these variables for further investigations is discussed.

Depression↗

[Self-injury or attempted murder--analysis of an unusual case].

An unusual case of self-injury involving several, partly deep penetrating stab wounds is described. A young emotionally disturbed consulting-room assistant accused her husband of having inflicted the injuries upon her in the course of an argument over custody of the children. An analysis of the injury pattern showed clear indications of self-injury and willfully transferred blood from punctures in the woman's fingertips to the clothes of the accused. The case demonstrates that in cases involving members of a medical profession and individuals with psychiatric disorders, the possibility of highly unusual types of self-injury should not be excluded. It further emphasizes the importance of a physical examination performed by a medico-legal specialist.

Adult↗

Evaluation of interleukin concentrations in amniotic fluid in preterm and term parturition and in oligohydramnios.

BACKGROUND: The goal of our work was to evaluate the activity of interleukin 1 beta, 6, 8, 12, and 18 in the amniotic fluid in preterm and term deliveries, and to specify the dependency between the amniotic fluid index (AFI) and the concentration of these interleukins. MATERIAL AND METHODS: Amniotic fluid (27 samples from preterm deliveries and 49 from term deliveries) was collected during cesarean section or in the course of amnioinfusion performed when the pregnancy was accompanied by oligohydramnios (AFI< or = 5cm). The amniotic fluid thus obtained was centrifuged at 1000 xg for 15 min. at a temperature of 4 degrees C, and the filtrate was kept at a temperature of -80 degrees C until assayed. The assays were done by the ELISA method, using ready antibody kits from 'R&D Systems'. A comparative analysis was done for the concentrations (expressed in pg/ml) of the individual interleukins found in the amniotic fluid from preterm and term deliveries, and for the amniotic fluid index (AFI< or = L5 and >5). The statistical analysis was performed using the Wilcoxon test. RESULTS: The increased level of IL-12 we found in the amniotic fluid from preterm deliveries and those complicated by oligohydramnios may indicate the participation of immunological mechanisms in the pathogenesis of oligohydramnios.

Amniotic Fluid↗

[Postmortem roentgen diagnosis of the skull].

In this prospective study, skulls of 164 dead bodies were x-rayed in two different planes. The findings were assessed independent to the results of the subsequent autopsy, however afterwards compared with the autopsy findings. In 86 cases (53.4%) x-ray findings were significant. Dislocated calvarium fractures were clearly visible on the x-rays, however non-dislocated calvarium fractures as well as fractures of the visceral cranium and skull base were difficult to detect. Gas and foreign bodies could easily be observed. Similar to the clinical assessment the indication for a post-mortem x-ray of the skull must consider the case history and the respective condition of the corpse (for example putrefaction, charred body).

Autopsy↗

[Management of sleep disorders from the geriatric psychiatry aspect].

Sleep disorders are a common phenomenon in patients of all age groups and often are not easy to influence. In geriatric patients sleep disorders are even more common and often are the main complaint. In addition to pharmacotherapeutic approach with a number of different psychotropic drugs non-drug procedures should also be used in the treatment of geriatric and psychogeriatric patients and combinations of different therapeutic approaches can be indicated. With every patient complaining of disturbed sleep a careful exploration of the origin of the sleep disorder is imperative prior to treatment.

Age Factors↗

[Secondary glaucoma in pseudophakia].

317 eyes of 288 patients who underwent cataract surgery with IOLs implantation since 1987--were examined. Secondary glaucoma was found in 31 eyes (9.8% in 10.8% with ACIOLs and in 8.6% with PCIOLs. The risk factors of intraocular pressure increasing were intra- and post operative complications, especially vitreous loss and posterior capsule lesions, as well as ACIOLs implantation in the eyes with extracapsular cataract extraction and planned PCIOLs. The changes of anterior chamber angle, visual function and methods of treatment in this type of glaucoma are also presented.

Adult↗

[Extremely varied rectal temperatures in 10 fatalities after a house fire--a contribution to the significance of body weight in cadaver cooling].

Eight children at the age of one to eleven years, their mother and uncle were victims of fire that had broken out in their flat. They all died of combined carbon monoxide cyanide poisoning. The rectal temperature of the bodies taken nearly eight hours later ranged from 16 degrees C to 29 degrees C. Using the rectal temperature time of death nomogram (Henssge 1982) with reference to corrective factors of the body weight (Henssge and Madea 1988) to find out when they died, the results corresponded with the enquiries made by the police except for three cases. The rectal temperature of the apparently intact bodies of the three youngest children whose weight ranged from 9 to 14 kilograms was comparatively high. The reason for this may be that reduction in diameter and in weight of the body causes a heating up in a smaller amount of time. This is why one has to be careful to use the nomogram with fire victims especially with those of low weight.

Body Temperature Regulation↗

[Identification of unknown cadavers in forensic medicine practice].

50 unknown dead were identified at the Institute of Forensic Medicine in Mainz (Germany) in the years between 1985 and 1993, most of them by dental records, x-ray comparison and morphological findings. This is equivalent to an overall success rate of 94.3%. In most cases unnatural causes of death were established (suicide, accident, and homicide). The male to female rate was more than 2:1. The increase of the number of unknown corpses since 1985 from 5% to nearly 10% of the total number of autopsies may be caused by increasing mobility and anonymity of the population.

Accidents↗