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Biomedical subjects

R Thiele

Publications and source records attributed to R Thiele.

At least 19 recordsLinked to original sources
PubMed1991

Induced hypertension as an approach to treating acute cerebrovascular ischaemia: possibilities and limitations.

As, after an stroke, the autoregulation of the cerebral vessels in the ischaemic region is disturbed to a high degree, it is, on principle, possible to improve the blood flow particularly in the zone surrounding the infarct (penumbra) by raising the systemic blood pressure. During a basic treatment with low-molecular dextrans (infukoll M40), 37 patients with an acute ischaemic cerebral stroke multiply underwent elevations in blood pressure up to systolic values of about 210 to 220 mmHg. A comparison with a control group (n = 44) who were treated with low-molecular dextrans revealed no differences in lethality on the 21st day after the stroke. However, a very good acute effect in terms of a short-term improvement was remarkable a result that is noteworthy also in future.

Acute Disease↗
PubMed1990

[Magnesium level in serum and erythrocytes in patients with chronic coronary heart disease without myocardial infarct].

In 62 patients with chronic coronary heart disease without myocardial infarction the magnesium content of the serum and the erythrocytes was determined by means of the flame atom absorption spectrophotometry in comparison to patients with infarction and a group of healthy test persons. In the patients with chronic coronary heart disease without acute myocardial infarction the magnesium content of the serum was significantly reduced on the first day after the pectanginous attack. No decreased magnesium level of the erythrocytes was present on the first and tenth day after the pectanginous attack.

Adult↗
PubMed1990

[Heart wall rupture as a grave complication of acute myocardial infarct].

The rupture of the heart wall is a severe complication of the acute myocardial infarction. We found it in 3.5% of the deceased patients with an acute myocardial infarction. The average age of these patients was 71 years. 75% of the patients died during the first five days after the event of the myocardial infarction. Apart from elderly patients with myocardial infarction such ones with a transmural myocardial infarction in the region of the left ventricle, an enlargement of the heart and signs of an insufficiency of the left heart, with a hypertension and diabetes mellitus seemed to be endangered. These patients need the most exact control and observation and in case of suspicion (symptomatology of angina pectoris which is continuing to exist) of a developing rupture of the heart wall and aimed diagnostics (echocardiography) and therapy must be begun immediately.

Acute Disease↗
PubMed1989

[Psychological stress conditions at an internal medicine intensive care unit. Analysis of a patient survey].

In an intensive therapy unit of internal medicine for the registration of the contendedness of the patients and the psychic problems of the patients a questioning was performed in the sense of a standardized interview. 55 patients were asked (30 males and 25 females). 89 per cent of the patients stated to have been understandably informed about their disease; 82 per cent said to have been given explanations as to the necessary diagnostic and therapeutic measures. Despite the altogether positive statements of the patients critical viewpoints were also the result which lead to changes.

Adaptation, Psychological↗
PubMed1989

[Arteriosclerotic changes of the brain and heart in relation to cardiac decompensation and arrhythmia in patients with cerebrovascular insufficiency].

In 150 patients with an acute cerebrovascular insufficiency we asked the following questions: 1. How often appear together the cardiac decompensation and disturbances of cardiac rhythm, 2. symptoms of hypertrophy and disturbances of cardiac rhythm and 3. arteriosclerosis of the cerebral and coronary vessels in deceased patients. The number of patients examined showed 26.7% of patients in whom a combination of symptoms of cardiac decompensation and disturbances of cardiac rhythm was present. The combination of signs of hypertrophy in the electrocardiogram and disturbances of cardiac rhythm was registered 39 times (26.0%). The arteriosclerosis was found in 68.2% of the patients in post-mortem examination. There was a high correlation between the sclerosis of the intracranial cerebral brains (65.9%) and the sclerosis of the coronary vessels (75.0%). It is referred to the possibilities of the prevention of the cerebrovascular insufficiency and the early therapy of hypertony, the cardiac decompensation and disturbances of cardiac rhythm.

Aged↗
PubMed1989

[Electrocardiography changes in patients with acute cerebrovascular insufficiency].

In patients with an acute cerebrovascular insufficiency a great number of disturbances of the cardiac rhythm is existing. In our investigations the absolute arrhythmia with auricular fibrillation and flutter (21%), ventricular and supraventricular extrasystoles (22%), atrioventricular blocks (13%) and patterns of bundle-branch block (25%) are concerned. Disturbances of the repolarisation of different size were present in 74% of all patients. A pathological QT-interval was to be stated in 31% of the patients examined. In the decreased patients a greater number of the disturbances of rhythm proved was to be observed. There were significant differences in disturbances of repolarisation. We stated a tendency to significance in the tachyarrhythmia. Apart from the sinus tachycardia the atrioventricular blocks were particularly distinct in the cerebral haemorrhage. The tachyarrhythmia was characteristic in patients with cerebral embolism. The mixed form of the cerebrovascular insufficiency was associated with a sinus bradycardia - above all as an expression of the cerebral pressure.

Arrhythmias, Cardiac↗
PubMed1988

[Drug-induced hepatitis after dihydralazine treatment with fatal consequences].

Adverse drug side effects of the antihypertensive substance dihydralazine have been increasingly observed in recent years. Damage is concentrated on the liver and is characterized by drug-induced hepatitis with confluent necrosis. Three cases (60 year old woman, 79 year old woman, 61 year old man) with lethal course after antihypertensive treatment, using dihydralazine are reported in this paper.

Aged↗
PubMed1987

[Development of adaptation of the cardiovascular system in rehabilitation phase III in patients with acute myocardial infarct].

In 30 men with proven myocardial infarction we performed a complex examination of cardiopulmonary capacity at the beginning (about 8 weeks after myocardial infarction) and at the end of rehabilitation phase III (5-6 months after infarction). Of these patients the results from microcatheterization at rest and during exercise are present. In addition we determined the relative quotient of effort (kpm/kg), maximum oxygen uptake (VO2 max) and maximum oxygen pulse (max O2 pulse). For the majority of the patients the parameters given suggested a significant improvement in the physical capacity after termination of rehabilitation. The improvements also concerned the functional capacity of the heart muscle, its increase in contractility during exercise. Conclusions are drawn about the selection of the patients for physical performance.

Adult↗
PubMed1987

[Analysis of patients with acute exogenous poisoning at an intensive care unit].

Over a period of 2 years patients with exogenic intoxications take 16% in the total number of patients of the department for internal intensive care. The cases in question were 43.3% males and 56.7% females. The average age of the patients with 31 years was low. The mortality was 2.4%. In the first place of the exogenic intoxications were intoxications with the groups of medicaments sedatives, hypnotics, tranquilizers, analgetics and antipyretics followed by intoxications with neuroleptics, beta-receptor blockers, antidepressives, antiepileptics and glycosides. The rate of complications was greatest in the mixed intoxications.

Adolescent↗
PubMed1986

[Diabetic coma].

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Bicarbonates↗
PubMed1986

[Hypoglycemia].

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Blood Glucose↗
PubMed1985

[Changes in the metabolic parameters in patients with acute myocardial infarct in the course of the rehabilitation phase II].

In a prospective study 32 patients with condition after acute myocardial infarction in the rehabilitation phase II were observed concerning the metabolic parameters, beta-lipoproteins, cholesterol, triglycerides, glucose, uric acid and lactate. At the beginning and at the end of the sports therapy the metabolic parameters were tested in rest as well as after exertion. The investigation led to the following results: 1. Increase of the physical efficiency from 134.0 to 142.0 Watt (non-significant); 2. the size of the biochemical parameters (beta-lipoproteins, cholesterol, uric acid, glucose) remained unchanged in the process of rehabilitation. 3. During the exertions themselves (hour of sports therapy, bicycle ergometer) in each case a non-significant increase of the beta-lipoproteins, the cholesterol and the values of uric acid appeared.

Adult↗
PubMed1985

[Stress factors in myocardial infarct patients before the appearance of myocardial infarct].

Apart from somatic risk factors and the smoking of cigarettes more attention in the development of the myocardial infarction must be ascribed to the psychosocial and psychoemotional stress and its false processing. For the judgment of the stress in patients with myocardial infarction a questionnaire was constructed. It contains those questions the answer of which showed significant differences in comparison to the persons with healthy coronary vessels. The inquiries were answered by altogether 110 patients with myocardial infarction. In order to obtain references to definite characteristics concerning the structure of the personality of our patients with myocardial infarction, we used the INR-questionnaire after Böttcher. In either sex moments of "self-stressing" dominate. Professional conflicts were mentioned more by men, familial problems more by women. Among others, definite characteristics concerning the structure of the personality (rigidity) of patients with myocardial infarction seem to be a reason for the deficient strain under stress or they increase the sensitiveness to stress. From the results of the examinations requirements to the psychic rehabilitation of patients with infarction are derived, which must be carried out parallel to the somatic rehabilitation.

Adaptation, Psychological↗
PubMed1984

[Possibilities of early diagnosis of left-heart insufficiency in acute myocardial infarction].

In 84 patients with an acute myocardial infarction clinical signs, measurement of the pressure of the pulmonary arteries and radiogramme of the thorax were used and compared for the estimation of the left heart insufficiency-particularly of an increase of a preload. The value of a standardized course series of radiogrammes of the thorax as a non-invasive investigation method in contrast to the invasive method of the pressure measurement of the pulmonary arteries was discussed. Advantages and disadvantages of the two methods were critically shown, since only in about 60% a correspondence was to be recognized.

Acute Disease↗