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Biomedical subjects

R Tandon

Publications and source records attributed to R Tandon.

At least 253 records · Page 14Linked to original sources
PubMed1981

Systemic hypertension and aortic obstruction in children.

Congenital coarctation of the aorta and acquired idiopathic obstructive aortitis result in systemic hypertension in children. The incidence of the former disease decreases--and that of the latter condition increases--from Europe to India to Thailand. The clinical profile of coarctation of the aorta as seen in India is similar to that described in the Western literature. Patients with idiopathic obstructive aortitis are generally desperately sick because of cardiac failure or neurological complications. Although it appears to be the result of an inflammatory process, the cause of aortitis is not known. Unless the clinical characteristics of the acute illness are defined investigations are not likely to help in establishing the cause of idiopathic obstructive aortitis.

Aortic Coarctation↗
PubMed1981

Red blood cell survival in patients with ventricular septal defect and patent ductus arteriosus.

Hemolysis of red blood cells (RBC) in stenotic or regurgitant cardiac valvular lesions has been felt to be due to mechanical trauma and shearing stress caused by turbulence of blood. RBC are also under a shearing stress from turbulence in high-pressure shunts, such as ventricular septal defect (VSD) and patent ductus arteriosus (PDA). The RBC survival time was measured in five patients with VSD and in 11 patients with PDA to determine if there was hemolysis of RBC. Six children without cardiac disease were also studied to obtain the control values for RBC survival times in th laboratory. Two patients with PDA were restudied one year postoperatively. Additional parameters studied were hemoglobin, packed cell volume, reticulocyte cell count, peripheral smear, and urinary hemosiderin. The hemoglobin values and the packed cell volumes were comparable in the two groups. The reticulocyte cell count was normal in all. Urinary hemosiderin was negative in all and the peripheral smear did not reveal abnormal red cell morphology. Mean red cell survival half-life in the two groups was identical. The red cell survival was abnormally low in two patients of PDA. Since one of these two patients had persistently low RBC survival postoperatively, the authors believe that the low red cell survival in this patient was unrelated to the presence of PDA. Based on findings in the small number of cases, the authors conclude that left to right shunt through a VSD or PDA is probably not associated with significant red blood cell destruction.

Adolescent↗
PubMed1980

Right ventricular cineangiography in Tetralogy of Fallot.

Accurate delineation of the anatomy of the cardiac chambers and the pulmonary vessels is a necessary component of the preoperative workup in Fallot's tetralogy. Selective right ventriculograms in shallow right anterior oblique and steep left anterior oblique views were used in the evaluation of 65 cases. Our observations indicate that these views display the anatomy of Fallot's tetralogy to a better advantage than do the conventional anteroposterior and lateral views.

Adolescent↗
PubMed1979

Ectopic aortic origin of the right pulmonary artery in tetralogy of Fallot.

A case is described wherein Fallot's tetralogy was associated with aortic origin of the right pulmonary artery. The left pulmonary artery was the continuation of the pulmonary trunk. Although a number of examples of Fallot's tetralogy associated with aortic origin of the left pulmonary artery are known, combination of Fallot's tetralogy and aortic origin of the right pulmonary artery is rare and has been described in only two cases previously.

Angiography↗
PubMed1979

Cardiovascular anomalies in conjoined thoracopagus twins.

Necropsy findings in 3 cases of conjoined thoracopagus twins are presented. Conjoined hearts were seen lying in a common pericardial cavity. In 2 cases the common atrial complex was incompletely divided into the atrial cavities of the twins by ridges arising from the floor of the cavity. In 1 case the atrial division was better defined and the interatrial septal defect of septum secumdum type was seen. Pulmonary veins opened normally into the atrial chamber only in 1 case, in the other 2 cases, these veins opened into the inferior vena cava and the liver respectively. Ventricular chambers were common in 2 cases with 3 rudimentary atrioventricular openings guarding the inlet and multiple VSD of muscular type. In 1 case one twin had 2 completely separated ventricular cavities and the other twin had partially separated ventricular cavities with a muscular VSD. Great vessels showed transposition in all the cases. In 1 case d-transposition of a rare variety was seen which was associated with a subaortic as well as subpulmonic conus. Persistent ductus arteriosus was a cmmon feature and valvular type of pulmonic stenosis was seen in 2 cases.

Abnormalities, Multiple↗
PubMed1976

Stenotic semilunar valve in persistent truncus arteriosus.

The clinical, hemodynamic, and pathologic findings in two newborn infants with persistent truncus arteriosus and stenosis of the truncal valve are described. In one case the anatomic features of the basic condition were classic, with a dysplastic semilunar valve which was mainly stenotic and also incompetent, while in the other the truncus arteriosus arose exclusively from the right ventricle and was almost exclusively stenotic. A ventricular septal defect was the only outlet for the left ventricle. In this case, mitral stenosis was also present and associated with a left-to-right shunt at the atrial level.

Aortic Valve Stenosis↗
PubMed1975

Cor triatriatum: study of 20 cases.

Twenty cases of cor triatriatum are reported. The diagnosis was confirmed by necropsy in 16 cases and at the time of operation in 4. The lesion occurred as an isolated anomaly in 7 cases; in 13, other associated cardiac anomalies were present. Three anatomic types of cor triatriatum were identified in the cases studied at necropsy: diaphragmatic (10 cases), hourglass (3) and tubular (3). The diaphragmatic type was also present in all four cases in which the diagnosis was confirmed at operation. Associated anomalies were found in five cases of the diaphragmatic type and in each case of the hourglass of tubular types. In isolated cor triatriatum the clinical findings were characteristic of pulmonary venous and arterial hypertension. In two cases, one with a communication between the right atrium and the accessory left atrial chamber and one with partial anomalous pulmonary venous connection associated with cor triatriatum, the clinical findings suggested a large left to right shunt with pulmonary arterial hypertension. The clinical findings varied in the cases with associated anomalies, and it was difficult to determine the cause of disturbance of the circulation.

Adolescent↗
PubMed1975

Ventricular inversion associated with normally related great vessels.

A patient with ventricular inversion with normally related great vessels and double inlet left ventricle is presented. the patient also showed features of Down's syndrome. Association of ventricular inversion with normally related great vessels is rare and leads to a basic functional state like that of complete transposition of great vessels derived from the connections between the ventricles and great vessels. The association of ventricular inversion with Down's syndrome observed in the case reported represents a rarity.

Aorta↗