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Biomedical subjects

R Taillefer

Publications and source records attributed to R Taillefer.

At least 73 records · Page 4Linked to original sources

Atrial natriuretic factor: a possible link between left atrium, plasma volume, adrenergic control and renin-aldosterone in the mitral valve prolapse syndrome.

The immunoreactive atrial natriuretic factor (ANF) was measured by radioimmunoassay after extraction with SEP-PAK cartridges in 16 hyperadrenergic patients with the mitral valve prolapse (MVP) syndrome. Plasma renin activity and plasma aldosterone were concomitantly measured by radio-immunoassay. Plasma and blood volumes were obtained indirectly after measurement of red cell volume. Norepinephrine and epinephrine were measured by a radio-enzymatic microtechnique. Seven out of 16 patients (44%) had high values of immunoreactive ANF. Blood volume was uniformly decreased in MVP patients, but this was more marked in patients with high ANF. There was a significant correlation between ANF and the reduction in blood volume. Plasma norepinephrine was not significantly different in patients with high ANF and low or normal ANF. Thus, some patients with the MVP syndrome may have both an increased adrenergic state and abnormal values of ANF. The interplay between these two neuro-endocrine disorders may account for some of the symptoms of these patients. The data confirm that this syndrome may be associated with a complex 'neuro-endocrine cardiovascular process'.

Aldosterone↗

Duplication of the superior vena cava: detection by radionuclide angiography.

The authors report three cases of duplication of the superior vena cava which were demonstrated by radionuclide angiography. Nuclear imaging was performed in order to demonstrate a left-to-right intracardiac shunt. Injection into the left external jugular vein demonstrated the presence of a duplication of the superior vena cava in addition to the presence of a shunt.

Adult↗

Radionuclide esophagogram.

The authors present their experience with the radionuclide esophagogram. Cases illustrating achalasia, diffuse esophageal spasm, nutcracker esophagus, oculopharyngeal muscular dystrophy, reflux esophagitis, gastroesophageal reflux, Barrett's esophagus, hiatal hernias, pharyngoesophageal diverticulum, and malignant tumors of the esophagus are included. The radionuclide esophagogram proved to be a useful procedure in the diagnosis and follow-up of many esophageal diseases.

Adenocarcinoma↗

Demonstration of a bronchobiliary fistula by 99mTc-HIDA cholescintigraphy.

A case of bronchobiliary fistula diagnosed by 99mTc-HIDA cholescintigraphy is presented. The fistula caused by a stenosing tumor of the left hepatic duct would probably have been missed without the use of delayed views and body fluids counting which increased the specificity of scintigraphic findings.

Bile Duct Neoplasms↗

Lymphoscintigraphic demonstration of intestinal lymphangiectasia.

The authors report a case of intestinal lymphangiectasia that was clearly demonstrated during abdominal lymphoscintigraphy using Tc-99m Sb colloid. Although lymphoscintigraphy has been used in many different clinical situations, this is, to our knowledge, the first scintigraphic description of this disease. Clinical and pathologic presentations of intestinal lymphangiectasia are briefly reviewed. Some possible approaches to the confirmation of the presence of a protein-losing gastroenteropathy are mentioned.

Adult↗

[Scintigraphic aspect of infantile cortical hyperostosis (Caffey's disease)].

Two patients with infantile cortical hyperostosis (Caffey's disease) are presented in whom radionuclide imaging with 99mTc-MDP and 67Gallium-citrate was performed to eliminate multifocal osteomyelitis as a diagnosis. The scintigraphic appearance of this relatively uncommon disease of children was similar to that obtained in multifocal osteomyelitis; all osseous lesions showed a marked uptake of both radiotracers. However, the distribution of abnormalities (mandible, scapulae) and the degree of extension (mainly diaphyseal) of the lesions are important characteristics in the scintigraphic differential diagnosis but bone radiographs are best used in making the diagnosis.

Aspirin↗