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Biomedical subjects

R T Sataloff

Publications and source records attributed to R T Sataloff.

At least 199 records · Page 11Linked to original sources
PubMed1988

Compatibility of autologous fibrin adhesive with implant materials.

A safe, effective method for securing autologous and alloplastic implants would benefit modern surgery substantially. We studied the effects of a new autologous fibrin tissue adhesive with various alloplastic implants and ear cartilage. Twelve rabbits had Proplast (a woven combination of Teflon and organic fibers), Silastic, Supramid polyfilament surgical sheeting, and ear cartilage implanted. One side of each animal had implants secured with tissue adhesive. The other, control side had identical implants placed in "subcutaneous tunnels." The tissue adhesive was biodegradable and produced no apparent toxic reaction, infection, or foreign-body reaction. It did not adhere to Silastic, but bound to the other implants. Glued implants had no more clinical or histologic evidence of inflammation than controls. Autologous fibrin tissue adhesive seems to be promising as a safe, biologic bonding material for securing certain alloplastic and autologous implants.

Animals↗
PubMed1988

Giant cholesterol cysts of the petrous apex.

The giant cholesterol cyst is a clinical entity distinct from cholesterol granulomas and other destructive lesions of the petrous bone. Preoperative assessment by computed tomographic scan and magnetic resonance imaging is extremely helpful. Attempts at total resection of the lesion are not necessary. Adequate surgical drainage may be established through the mastoid or middle fossa.

Adolescent↗
PubMed1988

Total temporal bone resection. A radical but life-saving procedure.

Traditional therapeutic approaches for malignancies of the temporal bone have produced unacceptably low survival figures. The morbidity and mortality associated with temporal bone cancer justify extensive surgery. Total temporal bone resection can be performed successfully in the hands of an experienced skull-base surgical team. By circumscribing the tumor rather than transgressing it, this procedure follows generally accepted principles of oncologic surgery. This procedure also shows promise in resection of extensive, carefully selected, recurrent benign tumors. We believe this approach offers hope for improved survival in patients with malignancy of the temporal bone. Further refinements in technique are suggested by each new case. Additional experience and long-term follow-up are needed to assess the efficacy of this procedure. The interest, expertise, and active participation of the operating room nursing team are critical to the success of this surgery. Ideally, not only intraoperative participation but also preoperative assessment and postoperative support should be routine. Close cooperation and extensive communication among the surgeons and nurses are essential.

Adult↗
PubMed1988

Autologous fibrin tissue adhesive for cerebrospinal fluid leaks: a controlled study of neurotoxicity.

Postoperative cerebrospinal fluid (CSF) leakage continues to be one of the most common and potentially serious complications following translabyrinthine surgery despite numerous strategies aimed at its prevention. Fibrinogen-based tissue adhesives may be helpful in decreasing this complication rate. Although commercial glues have been used widely in Europe (especially for dural repairs), they are not approved for use in the United States. Recent investigation has provided a relatively simple technique for producing a comparable autologous glue that obviates the risks of the commercial product. Since this glue will bind fascia, fat, and dura in the watertight fashion, it is potentially ideal for preventing CSF leaks. Experimental studies in rabbits reveal that autologous tissue adhesive can be used safely around intact nerves, suggesting it can be used safely to supplement fat, fascia, or muscle plugs for closing translabyrinthine defects. Clinical trials to test the efficacy of tissue adhesives in this application are currently under way.

Animals↗
PubMed1988

Transfacial resection of intracranial tumor.

Tumors of the skull base with intracranial and extracranial components pose special access problems. Traditional craniotomy and extensive external incisions produce morbidity that can be avoided in properly selected cases. Current surgical techniques extend previously described operations to allow good visualization and safe resection through the face for certain intracranial tumors. Meticulous attention to surgical techniques and wide exposure for complete tumor visualization are essential to ensure the safety of these procedures.

Adolescent↗
PubMed1988

Intralabyrinthine schwannoma.

In the case presented, an intralabyrinthine schwannoma was discovered during translabyrinthine eighth nerve section. Analysis of this case and the 22 previously reported cases of intralabyrinthine schwannoma highlights the difficulty in preoperative diagnosis of this lesion. Concerns are raised about the frequency with which this diagnosis may be missed and its implication in neurotologic surgery for vertigo.

Adult↗
PubMed1988

An easy guide to electronystagmography interpretations.

Although there are numerous text books and long articles written on electronystagmography, there are few comprehensive summary tables to assist in teaching ENG interpretation. The use of such a device, however, is particularly helpful for medical students, residents, audiologists, nurses, and medical specialists who do not interpret electronystagmograms regularly.

Electronystagmography↗
PubMed1987

Bilateral synchronous mixed tumors of the parotid glands.

Bilateral synchronous mixed tumors of the parotid glands are uncommon. In this case, they occurred in association with multiple benign tumors elsewhere in the body. The larger of the two parotid neoplasms was asymptomatic and undetected on physical examination, even after its presence had been established by computed tomographic scan.

Adenoma, Pleomorphic↗
PubMed1987

Autologous fibrin tissue adhesive for peripheral nerve anastomosis.

The sciatic nerve in rabbits was exposed, transected, and repaired using either of two methods. The experimental group had an autologous fibrin-based adhesive repair. The control group had conventional perineural suturing. The autologous tissue glue is similar in composition, handling, and performance to the commercially available European product Tisseel. It can be prepared quickly without sophisticated equipment or expense. Autologous glue obviates the risk of transmissible disease that has precluded approval of the commercial product for use in the United States. The glued anastomosis can be performed with accurate apposition and minimal trauma to the nerve. By making a fibrin cocoon, the anastomosis can be insulated. This provides some of the benefits of sheathed anastomosis while minimizing foreign body reaction. Functional evaluation and histologic results comparing the amount of anastomotic fibrosis, axonal regeneration, and alignment of fascicles showed glue to be as good as, if not superior to, conventional suture technique.

Animals↗
PubMed1987

Total temporal bone resection for squamous cell carcinoma.

Because of unsatisfactory results in treatment of malignant conditions of the temporal bone, a technique for total en bloc resection of the temporal bone and carotid artery was reported by Graham et al. in 1984. The procedure involves resection of the internal carotid artery, cranial nerves VI through XII, and structures adjacent to the temporal bone. Experience with two additional cases led to numerous modifications in the recommended procedure, as reported by Sataloff and Myers. Additional clinical experience with this technique and its complications has resulted in further modification. Additional pitfalls and specific changes in technique from previous reports are discussed in detail, including a new procedure to assure the adequacy of contralateral venous outflow.

Aged↗
PubMed1987

Morquio's syndrome.

Treatment of hereditary syndromes is still hampered by a scarcity of information. Morquio's syndrome is a mucopolysaccharidosis associated with chronic middle ear disease and with mixed or sensorineural hearing loss, although some patients with this syndrome have had normal hearing. This case is presented to report the occurrence of hearing loss and to report electronystagmographic findings for the first time.

Child↗
PubMed1987

Tinnitus and vertigo in healthy senior citizens without a history of noise exposure.

The prevalence of tinnitus and dizziness in healthy elderly adults has been uncertain. This study investigated 267 people between the ages of 57 and 91 1/2 years. The subjects had no history of noise exposure, systemic diseases associated with tinnitus or disequilibrium, and had normal otoscopic examination results. Twenty-four percent reported tinnitus. Five percent experienced dizziness. Additional studies will help clarify the prevalence of these symptoms in the elderly "normal" population.

Aged↗