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Biomedical subjects

R T Brodell

Publications and source records attributed to R T Brodell.

At least 19 recordsLinked to original sources
PubMed1995

The treatment of palmar and plantar warts using natural alpha interferon and a needleless injector.

BACKGROUND: The treatment of palmar and plantar warts is difficult and often frustrating. The need for multiple destructive treatments and recurrences after apparent cure are common. OBJECTIVE: The purpose of this study was to determine if intralesional natural alpha interferon might offer an effective alternative therapy for common plantar and palmar warts. METHODS: A series of 22 private office patients with palmar and plantar warts were treated with intralesional natural alpha interferon using a needless injector. We treated twice weekly for a minimum of 8 weeks or until clear. RESULTS: Sixteen patients (73%) showed complete clearing of their warts in a mean of 11 weeks of twice weekly treatment. Upon follow-up, which averaged 9.5 months, 17 of 21 patients (81%) remained clear of their warts. CONCLUSION: Natural alpha interferon by needless injector appears to represent an effective alternative treatment for palmar and plantar human papillomavirus lesions. Further study of this modality is indicated.

Adolescent↗
PubMed1994

A practical approach to antibiotic treatment in women taking oral contraceptives.

Clinical situations that require the use of systemic antibiotic therapy are common. Because millions of women choose oral contraceptives for birth control, the potential for interaction between these drugs frequently has to be considered. We review the available information and present a practical approach for dealing with this situation based on sharing responsibility with an educated patient.

Adult↗
PubMed1994

The conjunctival wart: report of a case and review of treatment options.

Human papillomavirus, a papovavirus, is the causative agent of all warts. There are at least 63 subtypes of this virus, certain ones of which are more likely to cause warts in particular locations or to be associated with malignancies. Over the last 6 years, HPV-6, HPV-11, and HPV-16 have been detected in both benign and malignant lesions of the conjunctiva. We report a patient with a large viral papilloma of the palpebral conjunctiva of the right lower eyelid. This case demonstrates that even very large viral papillomas can be treated successfully.

Adult↗
PubMed1991

The treatment of benign sebaceous hyperplasia with the topical application of bichloracetic acid.

Sebaceous hyperplasia is a benign lesion that occurs commonly on the face of older individuals. A variety of treatment options have been described, including oral isotretinoin, electrodesiccation, CO2 laser surgery, cryosurgery, and shave excision with curettage. Problems have been noted with these approaches. These techniques are more complex, less effective, require more time, or are more likely to scar than the procedure we describe. The treatment of sebaceous hyperplasia with bichloracetic acid is described with results presented after treatment of our first 20 patients.

Administration, Topical↗
PubMed1991

Office dermatologic testing: the KOH preparation.

A potassium hydroxide preparation is used to confirm the diagnosis of a superficial fungal skin infection. Adding black or blue-black ink to the potassium hydroxide solution highlights fungal organisms and distinguishes them from surrounding cellular debris.

Biopsy↗
PubMed1991

Office dermatologic testing: the scabies preparation.

Patients with scabies may present with urticarial, eczematous or excoriated papules, eczematous patches or, occasionally, nodules. It is often difficult to differentiate scabies from eczema, folliculitis, drug eruption or lichen planus. The classically described burrows are often not seen. The scabies preparation, as described in this article, will aid in making the proper diagnosis.

Clinical Protocols↗
PubMed1991

Office dermatologic testing: the Tzanck preparation.

Whether a vesicobullous disease is intraepidermal or subepidermal is often difficult to determine from the clinical examination. The Tzanck preparation can provide clues that aid in the diagnosis of a number of diseases. It is particularly helpful in confirming the diagnosis of herpes infection. This article outlines the materials and steps for performing this valuable test.

Azure Stains↗