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Biomedical subjects

R Straub

Publications and source records attributed to R Straub.

At least 109 records · Page 6Linked to original sources

Influences of endurance training on the ultrastructural composition of the different muscle fiber types in humans.

To investigate changes in the ultrastructure of the different muscle fiber types induced by endurance training ten sedentary subjects (five women and five men) were exercised on bicycle ergometers 5 times a week for 30 min. After 6 weeks of training there were significant changes in VO2max (+14%), in the percentage of type I (+12%) and type IIB fibers (-24%) as well as in the volume densities of mitochondria. The latter increased 35% in type I, 55% in type IIA and 35% in type IIB fibers. The relative increase in subsarcolemmal mitochondria was larger than in interfibrillar mitochondria in all fiber types. There was also a significant increase in the volume density of intracellular lipid in type II fibres. It is concluded that high intensity endurance training leads to an enhancement of the oxidative capacity in all muscle fiber types.

Adult↗

Equine leucocyte antigens in sarcoid-affected horses.

The distribution of equine leucocyte antigens (ELA) in horses affected by equine sarcoid tumours was determined and compared with unaffected controls. ELA-haplotype W3,B1 occurred more frequently in affected riding horses of Irish, Swiss and French background. The combined data for the three breeds resulted in a chi 2 value of 20.35 (P less than 0.0005 after correction). Simultaneously, ELA-specificity W11 was more frequently found in horses of Irish background, while W5 was found in Swiss and French horses with sarcoids. The combined data for haplotype W3,B1 and/or W5 specificity demonstrated, in the genetically closely-related Swiss and French horses, a highly significant difference in the occurrence of these haplotypes between affected horses and healthy controls (chi 2 = 28.69, P less than 0.00001 after correction). Thus, the results strongly suggest that the predisposition of horses to sarcoid is associated with or linked to the major histocompatibility complex.

Animals↗

[Parameters for the evaluation of endurance capacity in horses].

The incremental three work loads test as a basis test, and the one work load test, in which one measures the heart rate and the serum lactic acid concentration, lead to the performance index values V4 and V150. These values are of great practical importance in judging the performance capacity, the ability to be trained, the trainings effectivity, and determining the optimal work load for interval training.

Animals↗

[Depressive patients in institutional treatment. 1st results of an epidemiologic study of the Weissenauer Depression Ward].

Between the end of 1976 and the beginning of 1980 more than 700 patients were admitted to the Weissenau Depression Ward. The most important data were obtained by way of special questionnaires, and part of it will be presented in abridged form in the following paper. In respect of the distribution of sex and age, marital status, manner and background of admission, psychiatric case history, duration of hospitalization, nosological allocation, above all for the nature of depression, age, phenomenological and nosological distribution, course of illness, time of hospitalisation, and therapeutical success interesting information is gained.

Adolescent↗

Equine leukocyte antigen system. I. Serological studies.

Lymphocytotoxic alloantibodies have been recognized in primiparous mare sera and colostra using the two-step microcytotoxicity test. The antigens detected on the leukocyte membrane do not occur on the erythrocytes. After testing on a cell panel from unrelated horses, absorptions with leukocytes were carried out. The subsequent retesting of the serum reagents on a cell panel including cells from 24 families rendered possible a grouping of preliminary monospecific reagents characterizing 18 antigen specificities on the cell membrane.

Animals↗

[Comparison of evaluation scales and performance tests for measuring the severity of cyclothymic depressions].

Usually the severeness of cyclothymical depression is assessed by self-or arbiter's evaluation scales. These assessments are influenced by - mainly verbal - disturbing variables that hitherto may hardly be controlled. Measurements of performance provide less falsified results. However, they are influenced by the premorbid level of general intelligence and by the age of the patient. These disturbing variables, however, can be controlled rather well. Empirical investigations show that the assessment of the severeness of cyclothymical depression measured by performance tests of evaluation scales leads to different results. Nevertheless, both types of tests are valid for measuring depressions. Therefore, both are to be taken into account for assessment of severeness.

Bipolar Disorder↗

[Cyclothymic depression and performance. Comparison of the efficiency of agitated and non-agitated cyclothymic depression patients on a brief test of severe depression].

Agitated and non-agitated cyclothym depressive patients were compared relative to their results in a short achievement test for measuring degree of depression; the agitated patients worked significantly less slowly in two of the five subtests. These differences may exist premorbidly and can be explained by a theoretical concept of arousal. We propose to control the subject's activational states which -- besides the control of age and intelligence -- might possibly precise the test results relative to the depth of depression.

Adult↗