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Biomedical subjects

R Steinert

Publications and source records attributed to R Steinert.

At least 37 records · Page 2Linked to original sources

[Percutaneous transtracheal ventilation using Nu-Trake cricothyreotomy instruments and tracheoscopic follow-up examination].

Practicability and efficiency of the cricothyreotomy set Nu-Trake was investigated in corpses (n = 10) in the institute of Pathology and clinically in laryngectomy patients (n = 5) including endoscopical controls. The practicability proved to be good, the time needed to perform the coniotomy did not last longer than 2 minutes. But complications in the investigation on the corpses could not be avoided. These were missing the lumen of the trachea, perforation of the pars membranacea tracheae and fracture of the cricoid. The clinical investigation demonstrated a sufficient oxygenation and ventilation in all patients during the whole investigation period (30 min). This can be explained by the diameter of 7.2 mm of the used tube. Endoscopic controls showed a sufficient distance of the tip of the tubes from the pars membranacea tracheae and almost no bleeding within the trachea. Similar as with other coniotomy-technics the cricothyreotomy with the Nu-Trake set bears the risk of typical complications which have to be overcome by training of this important measure of emergency.

Aged↗

[Failed intubation with case reports].

Failed intubation in three patients is reported. All three patients suffered sudden, extreme impaired of mask-ventilation. Twice a coniotomy with subsequent tracheostomy proved to be life saving and without permanent injury. In the other patient tracheostomy had been attempted without success, and subsequent, successful, coniotomy could not prevent cerebral ischemia. Coniotomy is the only correct emergency operation for failed intubation with impaired mask ventilation. It must be followed by a standard tracheostomy with closure of the coniotomy wound to prevent permanent laryngeal damage.

Adult↗

[Sudden deafness today--a review].

Sudden deafness is not a disease in itself. Unilateral impairment of inner ear function of acute onset is a symptom of unknown origin. Recent results of basic science and clinical research favour an alteration of physiological properties and/or a variety of different diseases as a cause of this inner ear dysfunction. It is important to recognise these factors by audiometric and clinical investigations in order to differentiate the resulting inner ear dysfunction from sudden deafness. Our task is to find the cause in almost every case of hearing impairment so that the term "sudden deafness--of unknown cause" can be abandoned. So far we prefer a conservative treatment. Indicators of unfavourable prognosis should be assessed carefully since they demand special treatment, for instance tympanotomy.

Cochlea↗

[Cochlear potentials and reduced blood supply].

In cats the mean arterial blood pressure (MABP) was reduced to 40 or 30 mm Hg by controlled hemorrhage. In 3 animals the cochlea action potentials (CAP) are not changed between 30 and 380 Min by 40 mm Hg MABP. In 4 animals we saw a latent or permanent decrease of CAP between 4 and 115 Min by 30 mm Hg MABP. A singular experiment shows, that a CAP-decrease is caused by injection of an acetylcholin blockade substance. We did not find a correlation to the length of time of the ischemia and a CAP decrease. We found an exact correlation to the hypovolemic sympathetic palsy and a CAP decrease. In reduced blood perfusion the cochlea of cats is more resistant than the brain.

Animals↗

Superior limbic keratoconjunctivitis in contact lens wearers.

Forty patients with daily wear, cosmetic contact lenses (CL) presented with symptoms of ocular irritation and a keratoconjunctivitis clinically resembling superior limbic keratoconjunctivitis (SLK). Typically the patients were either successful hard CL wearers who changed to soft lenses and used a chemical aseptisizing solution or preserved saline solution, or successful soft CL wearers using salt tablets who switched to a preservative-containing system. In all cases, exposure to thimerosal-preserved solutions was documented. Upon discontinuation of lens wear, all signs and symptoms slowly resolved without permanent sequelae. Positive skin and ocular sensitivity reactions to thimerosal were present in one-third (5/15) of patients tested. Light and transmission electron microscopic examination of conjunctival specimens disclosed intercellular epithelial edema, pseudoepitheliomatous hyperplasia, acute and chronic inflammation, and decreased numbers of goblet cells. Exposure to thimerosal is implicated in the etiology of contact lens-superior limbic keratoconjunctivitis (CL-SLK).

Adolescent↗

[Tatooing of tumor borders in cancer of the oral cavity and oropharynx as a guide for orientation in radical operation after radiation].

To improve the local rate of success or the conversion of cancers of the cavum oris and of the oropharynx which are inoperable because of their local situation, preoperative radiation is carried out in cases where this is appropriate. The radiation and the radical operation must be coordinated with each other. For this purpose the borders of the cancer are marked by tatooing them with ink. The tatooing makes it possible both to judge the effects of the radiation accurately and to locate the borders of the tumor with the naked eye after radiation treatment in apparently healthy tissues. In this way it is possible to perform the radical operation with an adequate safety margin around the pre-therapeutic borders of the tumor. With this method the rate of success in tongue-body, tongue-ground and tonsil cancers can be improved.

Humans↗

[Indications, techniques and results of intermaxillary ligation in partial mandibulectomy].

In radical operations of tumors in the cavum oris and oropharynx partial mandibulectomy is sometimes necessary. With inter-maxillary ligatures using the fixation aids described (splints, prostheses and rubber rings) it is possible to achieve sufficient immobilization to permit the wound to heal, training of the mouth-opening muscles and a long-term treatment to prevent the scar from shrinking. Examples of the good functional and cosmetic results are presented with photos.

Humans↗

[What effect does ligation of the large neck arteries have on cochlear potentials?].

In guinea-pigs the course of summating potentials (SP) is observed. After the potentials have been identified by their typical form, their sensitivity to a reduction of oxygen, damage by streptomycin and adaptation to excessive noise, the quantity of the SP after ligature of the main neck arteries is recorded. After ligature of the external carotid arteries, the internal carotid arteries and the vertebral arteries on both sides, the SP remain active. This is presumably caused by anastomoses between the external carotid and subclavian arteries, the subclavian and spinal arteries, the external carotid and basilar arteries, and the double origin of the vertebral arteries on both sides. The subclavian arteries and the common carotid arteries can be ligated on both sides in random order. The SP remain almost unchanged as long as one vessel is open.

Animals↗

Pulmonary complications, ventilation and blood gases after upper abdominal surgery.

Forty patients who underwent elective cholecystectomy were examined preoperatively and during the first postoperative week by physical examination, measurement of FVC and FEV1, arterial pH and blood gas analyses, and chest x-ray. Postoperative pulmonary complications (p.p.c.) were detected in 30 (75%) of the patients. Simple auscultation was the most sensitive tool in discovering p.p.c., but 18 of the 30 patients with complications also had a pathological chest x-ray. Obesity, smoking postoperative naso-gastric tube and postoperative wound infection were predisposing factors for p.p.c. Six patients with preoperative pulmonary disease all had a progress in their lung pathology. There was no definite relationship of duration of anaesthesia or drainage of the abdominal wound to development of p.p.c. The patients with p.p.c. showed a deeper and more prolonged fall in Pao2 postoperatively than the normal group. None of the normals showed an arterial Po2 below 70 mmHg in the postoperative course, while 63% of the p.p.c. group did. FVC and FEV1 showed marked reductions from preoperative values on the first postoperative day, and then gradually increased to near preoperative values after 1 week. Arterial pH and Pco2 showed no definite changes during the postoperative course.

Adult↗