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Biomedical subjects

R Sosa Alamo

Publications and source records attributed to R Sosa Alamo.

7 recordsLinked to original sources

[Visceral leishmaniasis in childhood (author's transl)].

Authors present six cases of kala-azar in children under six years of age observed in the province of Seville, during a three year period. Ethiologic, clinical, evolutive and therapeutic aspects of this illness are analized. Two of the patients presented jaundice, in which a liver-spleen scan was performed and nothing else but the hepato-splenomegaly was found, as it was described in a previous case. Importance of visualizing leishmanias by bone marrow puncture for a true diagnosis is remarked.

Age Factors↗

[Favism (study of 8 families)].

This paper presents ten cases of total glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in individuals with hemolytic crisis after exposure to products of the fava been ("Vicia faba"). Three other cases of total G-6-PD deficiency and eleven partial deficit cases of the enzyme, without associated hemolysis were detected in a total of forty individuals belonging to eight families of the province of Seville examinated for G-6-PD levels. Important differences were noted in the G-6-PD enzyme dosage taken during the crisis and six and twelve months after. This fact was interpreted as a secondary effect to the elimination of the enzymopenic cells because of hemolysis. Data suggests the existence of a relatively stable form of G-6-PD that could explain the dissociation between the incidence of deficit in G-6-PD level in the general population and the reduced casuist of favism reported in our literature.

Adult↗

[Melitococcal hepatic encephalopathy].

A 5 year old child with brucellosis is described who developed severe liver disease with neuropsychiatric signs and electroencephalographic changes.

Brucellosis↗

[Familial erythrophagocytic lymphohistiocytosis (author's transl)].

A four-year old boy with familial erythrophagocytic lymphohistiocytosis is reported. The clinical picture was that of prolonged fever, hepato and splenomegaly, adenopathies and, in the terminal state, bleeding tendency and sligth jaundice. The laboratory data showed anemia, leucopenia and abnormal coagulation studies compatibles with disseminated intravascular clotting. The differential diagnosis with malignant histiocytosis is attempted from a histological point of view.

Bone Marrow↗