Biomedical subjects

R Soman

Publications and source records attributed to R Soman.

10 recordsLinked to original sources

PubMed2004

Spontaneously developing autoantibody to factor VIII in an elderly woman: diagnostic and therapeutic challenges.

An elderly woman with a continuously bleeding small wound was investigated for the presence of antibodies to FVIII using activated partial time-based screening and confirmatory tests. A late acting coagulation factor inhibitor was detected. The same was characterised to be a low titre antibody against FVIII (5.2 Bethesda units). Cryoprecipitate infusions, corticosteroids and topical desmopressin were unsuccessful in controlling the bleeding. Addition of cyclophosphamide brought about stoppage of bleeding and disappearance of the autoantibody.

Aged↗

PubMed2004

Purpura fulminans due to Enterococcus faecalis.

We report a case of a 73 year old man who developed purpura fulminans due to Enterococcus faecalis sepsis. The patient was treated successfully with oral linezolid. Early diagnosis of the microbial etiology of purpura fulminans is important. If Enterococcus faecalis is found as the causal organism, appropriate antimicrobial therapy may be used.

Aged↗

PubMed2003

Kikuchi Fujimoto disease with unusual features.

An uncommon case of Kikuchi Fujimoto disease with unusual associated serologic-autoimmune abnormalities and aseptic meningitis is reported for its rarity.

Adolescent↗

PubMed2002

Jugular venous thrombosis in HIV-seropositive man.

We report a patient with left jugular vein thrombosis, who was found to be HIV +ve, with increased homocysteine, decreased vitamin B12 and increased fibrinogen levels. Other markers for thrombophilia were absent. Whether HIV infection may be causally associated with venous thrombosis is discussed.

Adult↗

PubMed2002