[The role of Vitamin A and similar products in biological processes].
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Biomedical subjects
Publications and source records attributed to R Singer.
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This paper tries to demonstrate the diagnostic possibilities and limitations of CT in the facial skeleton. Our results stem from the examination of benign and malignant processes in 250 patients. This paper should demonstrate the different characteristics of the pictures obtained by CT and conventional polytomography. The main purpose of CT is not the diagnosis of fractures - here pluridirectional tomography is far superior - but the demonstration of space-occupying processes of benign and malignant tumours. CT cannot presently be applied to the investigation of different histopathological lesions.
During major breast surgery, we have achieved superior results by securing a dermal flap to the chest wall. This technique has been used successfully for the past three years with improvement in breast contour, prevention of ptosis, and less pronounced scarring than is produced by techniques of the past.
We report our experiences in 100 consecutive face lifts done in a well-equipped office operating room, and we believe the results answer the question about the safety of face lifts being done in this manner in a carefully screened population. With the application of our preoperative criteria for patient selection, the complication rate in these outpatients compares favorably with the reported rates in inpatient series of face lifts. Patient satisfaction has been higher, we feel.
Acid phosphatase activity was examined in normal and abnormal human semen of individuals not suffering from testosterone deficiency. No differences in enzymatic activity between the examined groups were observed. The presence of tartaric acid caused an inhibition of about 95% of enzymatic activity.
Thirty semens with sperm densities above 200 million per milliliter from patients with fertility disorders were examined for volume, motility, vitality, and morphology of spermatozoa, and for fructose content as well as for percentile decreases with time of activity and viability. In addition, blood levels of follicle stimulating hormone, luteinizing hormone, testosterone, and prolactin were estimated. Percentages of motility, vitality, and morphological normality, motility grades, and percentile decreases in both activity and viability were found to be comparable with those of oligospermic specimens. On the average, volume of semens were lower by about 30% than in normo- and oligospermia. 42% of the investigated semens had low fructose values (below 1 mg/ml). In about 60% of patients the prolactin levels were low (2-5 ng/ml). Follicle stimulating hormone, luteinizing hormone, and testosterone were either within normal range or slightly decreased. Despite the above abnormalities, the overall numbers of "normal" spermatozoa per ejaculate were not inferior to those usually present in normospermic specimens, suggesting that factors of presently unknown nature, involved in regulation of both proliferation and spermatogenesis, might be responsible for fertility disorders in these conditions.
The aim of the present work was to examine the sensitivity of human spermatozoa from oligospermic and normospermic semen samples to manipulations in the course of isolation by generally used procedures. To this end we performed protein and DNA estimations in spermatozoa isolated by procedures differing in rigorousness (washings with Ringer's buffer and a medium containing ficoll) as well as microscopic examinations of washed sediments. The results showed that the washed sediments contained, in addition to spermatozoa, materials containing protein and DNA, possibly deriving from the breakage of sperm cells. These materials increased in amount with the decrease of original sperm counts. We suggest that abnormal spermatozoa, whose percentage usually increases with the severity of oligospermia, are more sensitive to damage than the normal ones.
Folic acid was estimated in blood and seminal plasma of normo- and oligospermic men. Following folic acid administration (10 mg TID for 30 days), the levels in blood and semen increased. However, sperm counts, motility and DNA content of spermatozoa were not affected.
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The fluorescein test is a useful ancillary procedure for predicting the viability of breast flaps in reconstructive procedures after subcutaneous mastectomy or radial mastectomy.
A rare metastatic cancer in the soft tissues of the oral cavity has been discussed. The importance of a good clinical examination and the interrelationship between medicine and dentistry have been emphasized.
Investigations were carried out on implants of Al2O3 ceramic as secondary single toothe replacement in the lower jaw of young Beagle test dogs. Two basically different forms with altogether 7 variations were tested: the first three types of implants had conical roots and a further 4 had cylindrical roots. Common to all 7 types was an implantation shoulder which was tested for its ability to conduct the masticatory force via the cortical substance to the mandibular bone. All implants are at least under indirect masticatory strain; type 80-40-027-00 was directly under strain: part of the implant, shaped like a premolar protrudes through the gum directly into the oral cavity. Preliminary results show that cylindrical root shapes stood the test well. Their length was of no great importance. Conical root shapes without special provision of retention are not suitable. Firm positioning of the implant during introduction is of prime importance. A cortically placed implantation shoulder is not suitable for the conduction of the masticatory pressure into the mandibular bone in dogs.
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It is important that the dentist knows about disturbances of blood coagulation during and after hemo-dialysis, so that he avoids administration of platelet-inhibiting medication like aspirin and that he recognizes radiologically visible signs of insufficient dialysis in the jaws. Because of the reduced protection from infections, antibiotic prophylaxis should be carried out before every dental operation, the medication of choice being penicillin. Due to the high rate of infection by the hepatitis B virus, adequate protection is required.
Analysis of world literature appears to show that large hard odontomata of the jaw are relatively rare. 43 such odontogenous tumours are reported which were treated during 30 years in the maxillo-facial clinic in Heidelberg and in which the feasibility of mandibular reconstruction following partial resection was considered. The attention of dentists and maxillo-facial surgeons is drawn to odontomata, which are part of the symptom complex of Gardner's syndrome; a case is described where this rare disease presented.
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