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Biomedical subjects

R Silva

Publications and source records attributed to R Silva.

137 records · Page 8Linked to original sources
PubMedDate not supplied

Bilateral CNV associated with optic nerve drusen treated with photodynamic therapy with verteporfin.

PURPOSE: To report a case of bilateral choroidal neovascularization (CNV) associated with optic nerve drusen (OND) treated with photodynamic therapy (PDT) with verteporfin. METHODS: A 10-year-old girl with juxtapapillary CNV in the right eye and juxtapapillary and juxtafoveal CNV in the left eye associated with OND underwent PDT with verteporfin in both eyes. RESULTS: Visual acuity increased from 20/160 to 20/25 in the right eye and from 20/1000 to 20/25 in the left eye after two sessions of PDT and 2 years of follow-up. CNV showed no leakage after two PDT sessions in both eyes and no recurrence was observed. CONCLUSIONS: Subfoveal CNV is an uncommon complication of OND and excellent anatomic and functional results can be obtained with PDT.

Child↗
PubMedDate not supplied

Histopathology of essential fatty acid-deficient mice.

This histological study reports the pathological findings in mice deficient in essential fatty acids (EFAD). As shown by others, hyperplasia and hyperkeratosis were observed in skin. In addition, we reported hyperkeratosis of the esophagus and forestomach, severe degrees of atrophy of the seminal epithelium of testes, and diminution of the luminal content of epididymis, and the formation of clusters of lipid-laden macrophages in lungs. Hyperemia was also a systemic change in many organs. These alterations have not been reported in EFAD mice previously.

Animals↗
PubMedDate not supplied

[Utero-inguinal hernia].

A ten year old boy was operated for left inguinal hernia at age four years. Male gender was confirmed by sex chromatin. Y corpuscle and male genotype in chromosomal studies, and testicular function was tested by normal testosterone serum levels before and after parenteral human chorionic gonadotropin stimulus. On a second operation, two structurally normal testes and was deferens coexisted with Müllerian structures (rudimentary uterus and two Fallopian tubes of normal histological features) were found. A diagnosis of uterus-inguinalis hernia was made. Deficiencies at Müllerian inhibiting factor's secretion, activity or receptors have been postulated to explain this anomaly.

Child↗
PubMedDate not supplied

Intestinal perforation and vascular rupture in Ehlers-Danlos syndrome.

Ehlers-Danlos syndrome is a rare genetically determined disorder of connective tissue. Such patients often present challenges in clinical diagnosis and management. Dramatic life-threatening presentations include gastrointestinal perforation and vascular rupture, both occurring in the patient described. This case illustrates diagnostic features and therapeutic maneuvers important in the management of such complications of this disorder.

Adult↗