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Biomedical subjects

R Shields

Publications and source records attributed to R Shields.

At least 145 records · Page 8Linked to original sources
PubMed1973

Pattern of gastric emptying after vagotomy and pyloroplasty.

The pattern and rate of gastric emptying have been studied in 16 patients before and after vagotomy and pyloroplasty. The rate of emptying, expressed as half life in minutes, was not greatly changed by operation. After operation, however, there was a rapid initial phase of emptying, particularly marked in patients who had post-vagotomy diarrhoea.

Chromium Isotopes↗
PubMed1973

The effects of vagotomy on the intestinal handling of water and electrolytes.

A technique of intestinal perfusion has been used to investigate the effects of vagotomy on the intestinal handling of water and electrolytes. The capacity of the vagotomized jejunum to absorb water and electrolytes was found to be unimpaired, even in patients who had severe postvagotomy diarrhoea.

Cholecystectomy↗
PubMed1972

Mechanism of hormonal induction of tyrosine aminotransferase studied by measurement of the concentration of growing enzyme molecules.

Proteins labeled in cultured hepatoma cells grown in the presence of radioactive amino acids and pactamycin consist primarily of growing polypeptide chains initiated before addition of the antibiotic. Nascent tyrosine aminotransferase (EC 2.6.1.5) molecules were labeled in this way, and their radioactivity after completion was measured immunologically. Cells exposed to the synthetic adrenal steroid, dexamethasone, contain 10- to 18- times as much nascent enzyme as uninduced cells. These results indicate that induction control is not at the level of polypeptide-chain elongation or release, but probably operates on either the amount of messenger RNA or the rate of specific polypeptide-chain initiation.

Amino Acids↗