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Biomedical subjects

R Sekuler

Publications and source records attributed to R Sekuler.

At least 37 records · Page 2Linked to original sources

Self-reported visual problems of older drivers.

We conducted a survey in order to gain insights into the reasons older persons decide to give up driving. Our survey focused on vision. We probed the relationship between visual deficiencies and driving status by asking older people about the problems they encountered while performing routine visual tasks. The results showed that older persons who had recently given up driving reported more visual problems than did their driving counterparts. These problems related to difficulties in dynamic vision, visual processing speed, visual search, light sensitivity, and near vision. The results suggested that older persons are sensitive to their own visual deficits and that this awareness influences decisions about driving.

Activities of Daily Living↗

Direction perception in complex dynamic displays: the integration of direction information.

We created random-dot cinematograms in which each dot's successive movements were independently drawn from a Gaussian distribution of directions of some characteristic bandwidth. Such a display, comprising many different, spatially intermingled local motion vectors, can produce a percept of global coherent motion in a single direction. Using pairs of cinematograms, direction discrimination of global motion was measured under various conditions of direction distribution bandwidth, exposure duration, and constancy of each dot's path. A line-element model gave an excellent account of the results: (i) over a considerable range, discrimination was unaffected by the cinematogram's direction distribution bandwidth; (ii) only for the briefest presentations did changes in duration have an effect; (iii) so long as the overall directional content of the cinematogram remained unchanged, the constancy or randomness of individual dots' paths did not affect discrimination. Finally, the line-element model continued to give a good account of the results when we made additional measurements with uniform rather than Gaussian distributions of directions.

Discrimination, Psychological↗

Visual changes in daily life throughout adulthood.

A pair of surveys asked healthy adults about their everyday visual problems. Participants ranged in age from 18 to 100 and were screened for major visual impairment. Respondents rated the frequency of difficulty they had performing visual tasks such as reading, recognizing objects, picking out a face in a crowd, seeing in dimly lit environments, seeing moving objects, and so on. The surveys revealed five dimensions that declined with increasing age: visual processing speed, light sensitivity, dynamic vision, near vision, and visual search. The percentage of respondents reporting a decline in these visual dimensions increased two- to sixfold across the adult life span. Varying rates of visual decline for different tasks suggest that various aspects of vision age at different rates.

Activities of Daily Living↗

Direction-specific improvement in motion discrimination.

With training, an observer's ability to discriminate similar directions of motion gradually improves. A series of studies reveals that this improvement, (1) is restricted to the trained direction and other, similar directions, (2) persists for at least several months, (4) shows appreciable, but not complete, transfer between the two eyes, and (5) is largely restricted to the stimulated region of the field. Moreover, the improvement in direction discrimination does not produce a concomitant change in detection thresholds. In all likelihood, most of the improvement in direction discrimination represents a change in visual function, rather than changes in nonsensory processes.

Discrimination, Psychological↗

Ocular fixation control as a function of age and exposure duration.

In previous work we reported that fixation stability did not deteriorate in older adults over relatively long viewing durations. In the present study we reanalyzed the data to examine potential aging effects on fixational control for viewing durations typically used in psychological experimentation. Monocular eye movements were recorded in 12 older and 12 younger observers using a dual Purkinje image technique, while observers fixated a stationary target. The two-dimensional scatter of eye positions was measured during nine viewing durations ranging from 100 ms to 12.8 s. Fixational control of the two groups was comparable at all of the viewing durations. Both younger and older observers were able to maintain fixation within an area several times smaller than the size of the fovea. Implications for aging studies that use briefly presented visual stimuli are discussed.

Adult↗

A "hidden" deficit in central vision in diabetic pan-retinal photocoagulation patients.

Adaptation ability in the center of vision was tested in diabetic patients treated with pan-retinal photocoagulation for diabetic retinopathy and in normal control subjects. This was accomplished with a specially designed contrast sensitivity testing regimen. Patients with retinopathy showed "hidden" deficits, losses in adaptation ability that could not be measured by standard clinical tests, such as visual acuity. This new test thus quantifies a previously unmeasured visual problem that affects the everyday visual function of these patients.

Adaptation, Ocular↗

Improving visual perception in older observers.

Younger observers (M = 21 years) proved to be better than older observers (M = 68 years) at discriminating one direction of motion from another, highly similar one. Several days' practice steadily improved performance for both groups equally. Improvement was well restricted to the direction with which that observer practiced, and the full gains were retained for at least 1 month. Control measurements with various degrees of optical blur demonstrate that direction discrimination does not require a well-focussed retinal image. This rules out optical factors as the potential cause of the prepractice differences between groups.

Adult↗

Visual localization: age and practice.

Older people seem to be highly susceptible to the distracting effects of irrelevant or interfering visual stimuli. We studied this susceptibility using visual displays in which observers had to localize the position of a face. When a face appeared in isolation, observers of all ages did equally well; when distracting stimuli surrounded the face, older observers alone performed poorly. Brief periods of practice produce substantial and long-lasting improvement in performance.

Adult↗

Contrast sensitivity during provoked visual impairment in multiple sclerosis.

Many patients with multiple sclerosis have subjective visual complaints that are intensified by exercise (Uhthoff's symptom). We report a case demonstrating the utility of contrast sensitivity testing in such visual complaints. Contrast sensitivity was measured before and after exercise in a multiple sclerosis patient with Uhthoff's symptom and in two healthy control subjects. A short exercise period reduced the patient's contrast sensitivity for some target sizes, but had no effect on his visual acuity; a longer exercise period produced a greater, more uniform loss of contrast sensitivity and also reduced visual acuity. Contrast sensitivities and visual acuities of the control subjects were not affected by exercise.

Adult↗

Visual fixation stability in older adults.

Visual fixation of a small, stationary target was measured in 12 young observers (mean age = 22 yr) and in 12 older observers (mean age = 70 yr). The two groups' fixation behavior did not differ on various dimensions of fixation stability: mean fixation area, intra-subject variability, or changes in fixation over successive test periods. Connections between these results and age-related changes in the oculomotor system are discussed.

Adult↗

Role of the crystalline lens in the spatial vision loss of the elderly.

This study examined the contribution of the crystalline lens to the spatial contrast sensitivity loss experienced by many healthy older adults. Spatial contrast sensitivity was measured in three groups of adults: older adults who had undergone cataract extraction and intraocular lens (IOL) insertion; older adults who were in good ocular health (agematched to the first group); and young adults also in good ocular health. Older adults had decreased contrast sensitivity at higher spatial frequencies compared to young adults, agreeing with earlier reports. In addition, both groups of older adults had similar contrast sensitivity at higher frequencies, contrary to what would be expected if the aged, noncataractous crystalline lens significantly hampered contrast transfer in the healthy older eye. Results imply that the crystalline lens is not primarily responsible for the spatial sensitivity loss of healthy older adults. Furthermore, these data indicate that for at least some IOL patients, spatial vision can be restored to a level similar to their agemates who have no history of lens opacity or ocular disease.

Adult↗

Coherent global motion percepts from stochastic local motions.

A percept of global, coherent motion results when many different localized motion vectors are combined. We studied the percept with dynamic random dot kinematograms whose elements took independent, random walks of constant step size; their directions of displacement were drawn from a uniform distribution. The tendency to see global, coherent flow along the mean of the uniform distribution varied with the range of the distribution. Psychometric functions were obtained with kinematograms having various step sizes and element densities. The changes in the psychometric function with step size and density are consistent with Ullman's "minimal map theory" of motion correspondence.

Form Perception↗

Structural modeling of spatial vision.

A linear structural model of mechanisms underlying spatial vision was generated from the variance-covariance matrix of contrast sensitivity data. The data had been collected on a large group of observers ranging in age from 19 to 87 yr, using gratings of 0.5-16 c/deg spatial frequency. Structural models incorporating various numbers of spatial frequency-tuned mechanisms were compared, with a three-mechanism model giving the best account of the data. The same analysis was applied to contrast sensitivity data simulated from Wilson and Bergen's (1979) model. When the stimulated data covered 0.5-16 c/deg, only three mechanisms were needed to give a satisfactory account of the data; when the simulated data covered 0.25-16 c/deg, four mechanisms were required. Peak sensitivities and bandwidths of the mechanisms extracted from the simulated data resembled those extracted from the real, population data. This reinforces the idea that at an early stage of human vision a small number of spatially-tuned mechanisms are operative. In addition, the outcome of analyses with both real and simulated data illustrate the potential value of linear structural models for vision research.

Adult↗

Contrast sensitivity throughout adulthood.

Previous studies of spatial contrast sensitivity in adulthood have produced conflicting results. To clarify the situation, we measured contrast sensitivity functions on a large sample of adults (n = 91), ranging in age from 19 to 87. All observers were free from significant ocular pathology and were individually refracted for the test distance. Sensitivity for stationary gratings of low spatial frequency remained the same throughout adulthood. At higher spatial frequencies, sensitivity decreased with age beginning around 40 to 50 years. When a low spatial frequency grating was drifted, young adults' sensitivity improved by a factor of 4-5 over sensitivity to a static grating; this motion enhancement was markedly diminished in adults over 60 years, implying an impairment of temporal processing in the elderly. Reduced retinal illuminance characteristic of the aged eye could account for a large part of older adults' deficit in spatial vision, but appeared to play little role in their deficit in temporal vision.

Adult↗

Visual manifestations of biological aging.

Changes in the peripheral visual system with age are candidates for inclusion in an index of biological aging. Accommodative amplitude and pupil diameter seem particularly promising candidates. Their advantages and limitations are considered, as are those of behavioral measures of other visual functions.

Accommodation, Ocular↗