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Biomedical subjects

R Scognamiglio

Publications and source records attributed to R Scognamiglio.

At least 127 records · Page 7Linked to original sources

[Correlations between studies with plain radiography and with cineventriculography in subjects with prior myocardial infarct].

In 86 subjects wiht healed myocardial infarction the reliability of cardiothoracic ratio (C/T), of the left half-diameter (EDTS/m2) and of the overall subjective evaluation of a standard chest X-Ray plate has been tested by comparison to quantitative data drawn by selective cineventriculography. C/T and EDTS/m2 are scarcely reliable, whereas subjective evaluation allowed a separation among different groups of patients, though with wide overlap. Right anterior oblique and lateral views, and the evaluation of the third aortic arch were more useful than left anterior oblique and lowered apex.

Adult↗

[Left ventricular-right atrial communication. Diagnostic and therapeutic aspects: report of 16 cases (author's transl)].

16 cases of left ventricular-right atrial communication are reported. The most consistent clinical features, suggestive of this condition, were: auscultatory findings of V.S.D., electrocardiographic patterns of right atrial enlargement and biventricular hypertrophy, considerable right atrial enlargement coexisting with signs of left-sided cardiac enlargement and increased polmonary vascularity to Xray examination, echocardiographic fluttering of the tricuspid valve. Cardiac catheterization revealed an increased oxygen content in the right atrial or ventricular blood without the passage of the catheter through an A.S.D. The definitive diagnosis was established by left ventricular angiocardiography which demonstrated immediate opacification of a dilated right atrium through a septal defect; the location of the septal defect in the cardiac septum was attempted. In patients who suffered from a large left to right shunt were recommended for surgical treatment also in view of the relatively bad tolerance of this defect and low operative risk. There were two deaths: one baby died of early congestive failure. 9 cases were operated upon with one immediate postoperative death. The remaining, controlled by clinic follow-up, had good results.

Adult↗

[Isolated mitral stenosis: systolic and diastolic dynamic geometry of the left ventricle. Integration with several hemodynamic parametres (author's transl)].

75 patients with isolated mitral stenosis were studied. Particular attention was paid to the integration of the parametres VTD, FE, mitral area, pulmonary artery pressure and dynamic systolic and diastolic geometry of the left ventricle. The existence of isolated MS with alteration of the left ventricular function not depending on the alterations of the preload and the forms with raised FE, was demonstrated. A classification into 6 groups was made, each characterized by special geometric modalities of contraction and relaxation. A significant compensation of several of the parametres of systolic mecanism (hyperkinesia) and diastolic (SERP) dynamic geometry was observed. It was therefore concluded that a more precise definition of the interaction of ventricular function with left atrial function is necessary.

Cardiomegaly↗

[Study of left ventricular function. Part II: systolic perimetric variations (author's transl)].

New parameters for the study of ventricular dynamic, which analyze the perimetric dimensional variations of the ventricular margin on the cineventriculographic projective plain, were introduced. Three usable methods for these determinations are described: 1) the systolic dimensional variation of the total perimeter; 2) the contribution to the total perimetric length and the systolic shortening of the anterior and posterior wall; 3) the contribution of the telediastolic and the telesystolic length to the anterior or posterior wall and the systolic shortening (in mm/m2 of the corporeal surface and in the percentage of the respective telediastolic length) of each marginal region.

Angiocardiography↗

[Primitive cardiomyopathies: dynamic geometry of left ventricular contraction].

51 patients with primitive cardiomyopathy were studied and classified (5 groups) on the basis of hemodynamic parametres and the modalities of left ventricular contraction: the first group was made up of patients with "frontal sector" hyperkinesia, normal ejection fraction and without any dynamic obstruction of the ventricular flow; the second, of patients with hyperkinesia "frontal and rear sector" raised ejection fraction and with dynamic obstruction; the third group was composed of patients with "frontal sector" hyperkinesia, reduced motility of the mitralic valvular level with appearance of insufficiency (maintained in the subsequent groups) and depression of the ejection fraction; dynamic obstruction was present. Groups IV and V included patients with progressive extension of hypokinesia to all marginal regions, up to the contraction pattern characterized by "serious and diffused hypokinesia". To conclude, a correlation of the contraction patterns is made, characterizing the various groups with a pathophysiological interpretation.

Adult↗

[Study of normal left ventricular volume (author's transl)].

A study of left ventricular volume was carried out on ten normal subjects. The average values and the standard deviations of the end-diastolic (EDV) and end-systolic volumes (ESV), the systolic throw and the ejection (EF) are reported. They were obtained by using the single-plane cineventriculography method in the OAdx projection of 30 degrees.

Angiocardiography↗

[Quantitative evaluation of the systolic displacement of the left ventricle profile. A cineventriculographic study (author's transl)].

A new method for evaluating the systolic displacement of the left ventricle profile is proposed. It rests on the definition of an intracardiac axis and the identification of equivalent points on cardiac end-systolic and end-diastolic silhouettes separately. Displacement in then evaluated by means of vector methods. The results in ten normal subjects are reported. Systolic displacement is visualized by means of maps, uhich reflect the geometric properties of left ventricle normal contraction.

Angiocardiography↗

[Lymphocyte subpopulations in inflammatory periapical lesions. A histopathological and immunohistochemical study in 10 cases].

The authors, thanks to the application of monoclonal antibodies, as well as the immunohistochemical technique of APAAP, have traced the qualitative and quantitative features of inflammatory cells implied in periapical lesions. Moreover ten patients, of whom 6 males and 4 females aged between 20 and 60 have been tested. The immunohistochemical reactions revealed a heterogeneous population of B and T (T4-T8) lymphocytes, together with myeloid trunk cells (granulocytes and histiocytes). The B lymphocytes form nearly 31.5% of all the inflammatory cell, whereas the T types form about 55.8. The granulo-histiocyte part implies 11.1% of all the inflammatory cells themselves. The average percentages of the roted inflammatory cells have been compared with two diagnostic categories of periapical granuloma and periapical cyst. However, by comparing the obtained results with the ones described by other authors, we notice agreement as for as qualitative analysis is concerned, while as for quantitative analysis, some differences are proved. Finally, this situation shows that the quantitative demonstration of inflammatory cell populations is only a moment in the development of immune reactions in the inflammatory tissue.

Adult↗