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Biomedical subjects

R Schwarze

Publications and source records attributed to R Schwarze.

At least 37 records · Page 2Linked to original sources

[Mycologic monitoring of newborn infants at risk during preventive administration of nystatin].

Altogether 80 newborns at risk were prophylactically treated with 3 x 150,000 IU nystatin/d per os for 14-21 d respectively on every second day for 14-21 d. The content of yeasts in the faeces was determined. In preterm infants with birth-weight below 1500 g the intestinal yeasts--especially Candida albicans--persisted much longer during nystatin application than in infants with higher birthweight and longer gestation-time. In newborns at risk, daily nystatin doses of 3 x 150,000 IU/d are recommended for the duration of disposition for systemic candidosis.

Candida albicans↗

[Endophlebitis hepatica obliterans. Unusual cause of liver insufficiency in early childhood in a dizygotic twin].

Findings recorded from obliterative hepatic endophlebitis are described in this paper and are compared with international literature. They had been obtained from a male twin who had died with clinical symptoms of hepatic failure. Differential diagnosis of liver insufficiency in early childhood is discussed in some detail. Also recorded was obliterative angiitis of intramural blood vessels in the ileum. Systemic vasculitis is postulated, possibly developed on the basis of an immunological reaction. Intra-uterine infection had probably been the most likely cause.

Budd-Chiari Syndrome↗

[Pneumothorax and subvesical urinary tract obstruction in newborn infants--a pathogenically related symptom complex].

Within a period of 3 years 4 mature male neonates were observed with an unusual complex of symptoms: subvesical obstruction (valve) with spontaneous pneumothorax/pneumomediastinum. All infants showed immediately postnatal respiratory insufficiency. There are pathogenetical relations between renal and urinary tract malformations and pulmonary changes, which are recognized in Potter's sequence with pulmonary hypoplasia. The authors postulate a deranged dynamic of pulmonary fluid by oligohydramnios, causing increased vulnerable lungs also in such cases without typical x-ray signs of pulmonary hypoplasia. A spontaneous pneumothorax/pneumomediastinum in newborn infants should be the sign to perform nephro-urologic (sonographic) examination.

Humans↗

Pathogenetic significance of venous hyperoxaemia in retinopathy of prematurity.

Ten underweight newborns with severe retinopathy of prematurity (ROP) and 18 newborns with slight changes in the sense of ROP were compared with 66 healthy infants. The distribution of 13 possibly pathogenetically effective features in these 3 groups of patients was studied by means of variance analysis. The greatest significance resulted for multiple blood transfusions and exchange transfusions. From this it was concluded that the toxic oxygen effect on the immature retina was probably more dependent on the venous PO2 (determined by Hb concentration, O2-affinity, arterial PO2, and blood flow) than on the isolated arterial PO2.

Analysis of Variance↗