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Biomedical subjects

R Schrage

Publications and source records attributed to R Schrage.

25 records · Page 2Linked to original sources

[The timing of tubal ligation (Author's transl)].

In spite of medical or mixed medical and social indications, the sterilization by tubal ligation is frequently not carried out or done very late as in sterilization combined with a therapeutic abortion. This is borne out by the review of case histories and consultations of patients who had a sterilization operation other than post-partum, multiparous patients who had no sterilization, multiparous patients who had sterilization post-partum and patients who had an application for therapeutic abortion rejected and patients who had a therapeutic abortion with concomitant sterilization. The medical indications, medical social indications, the duration of the disease, the desire for child bearing, the social conditions and the family conditions were of such nature that in 29-80 percent of the cases under review sterilization could have been carried out at an earlier time. The relatively high incidence of women who presented with indications for sterilization but whose sterilization was delayed shows that more active individual counseling regarding sterilization by the attending physician is desirable. If necessary the physician should raise the question of sterilization and discuss the problem with the patient. This type of counseling would insure that the patient can make an informed decision and would minimize the psychological side effects and after-effects of sterilization.

Abortion, Legal↗

[Urocytogram in the treatment with bleomycin].

Even though Bleomycin is excreted in the urine in high concentrations, side effects in the urinary tract due to the chemical nature of this compound are seldom observed. With respect to treatment of gynecological carcinomas, it is, therefore, important to examine the effect that Bleomycin when treatment involves the use of Endoxan. Cytologically, one finds an increase in desquanmation of the transitional epithelium and an increase in degenerate cell forms. The homogenous eosinophilic cellular inclusions which are observed, are specific for neither Endoxan nor for Bleomycin treatment. The antibiotic effect of Bleomycin results in an aseptic cystitis. The urocytogramm is suitable for examining the epithelial changes of the urinary tract in context with the gynecological carcinoma treatment and also for determing tumor breakthough into the bladder.

Bleomycin↗

Amniotic fluid cells in the second trimester of pregnancy.

The cell types of amniotic fluid in the second trimester of normal pregnancy are described and compared with the findings in the literature. Two hundred cell samples obtained by amniocentesis in pregnancies without known fetal neural tube or skin defects were studied. Anucleated and nucleated squamous epithelial cells of superficial and intermediate layers were found, as were macroforms of superficial cells. Parabasal cells were infrequent. Parabasallike cells were of amniotic origin. Other amniotic cell types, such as "balloon," or "goblet," cells, umbilical cord cells and hyperchromatic placental amniotic cells, were observed. Urothelial cells and nonepithelial cells, such as histiocytes and macrophages, were found. In several cases, "minicells" were seen; their different sites of origin are discussed.

Amniotic Fluid↗