[Transformation of diazonium salts with sodium borohydride].
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Biomedical subjects
Publications and source records attributed to R Schmitz.
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A randomized prospective study of low-dose heparin was performed in 89 surgical patients during and after Bassini-Lotheissen repair. The patients were divided into two groups: (1) Low-dose heparin: 5000 units 2 hours before operation and 5000 units every 8 hours for 5 days after the operation. (2) Dextran 40 (Rheomacrodex); administered during the operation, with an additional infusion of dextran (500 ml/day) for the next 3 days. The frequency of wound complications in 45 the heparin-treated patients was 22.0% (comprising 10 hematomas), compared to only 4.5% in the dextran-treated patients (n = 44 patients). These findings are significant (p < 0.05). Low-dose heparin should therefore be administered routinely only to patients with increased risk of thromboembolism.
In a prospective trial we evaluated the diagnostic value of ultrasound imaging in the diagnosis of injuries to the anterior syndesmosis of the ankle joint. In an initial series of 20 patients using a basic standard ultrasound machine (Siemens Sonoline SL 1 with a 7.5 MHz piece) and a simple dynamic testing protocol as described in this article we found a significant difference between the ultrasound result for the ruptured syndesmosis versus non rupture and a specificity similar to that of arthrography. We conclude that ultrasound imaging is a useful tool in the diagnosis of syndesmotic rupture. Given the statistical significance of these results we feel confident that-despite the small amount of patients of this series and after an individual learning curve-ultrasound will eventually replace arthrography as the standard of investigation for this type of injury.
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Different compressive bandages for chronic venous deficiency and lymphedema, are categorized. These categories are not based on the bandage technique itself, but on its effect. The aims of the compression vary in accordance to whether the case involves a diffuse edema brought on by chronic venous deficiency or by lateral trophic problems following malfunctioning of the perforating veins, or difficulties in transporting tissue from the lymphedemas. These various etiological factors must be taken into consideration in the design and use of compressive bandages.
The ultrasonic or Doppler probe must become a routine instrument in phlebology. It makes it possible to not only to demonstrate arterial circulatory disorders, but also to approximately estimate the level of secondary effects on the peripheral circulation. Once he knows that there is an arterial pathology, the phlebologist can then decide whether to apply a compressive bandage, to prescribe a degressive support stocking, to inject sclerosing drugs or to resort to foot surgery.