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Biomedical subjects

R Scheig

Publications and source records attributed to R Scheig.

At least 19 recordsLinked to original sources

Evaluation of tests used to screen patients with liver disorders.

There is no one test of liver function. Routine laboratory tests that are useful in screening for liver disease and following its course include serum AST, ALT, alkaline phosphatase, protein electrophoresis, prothrombin time, and bilirubin levels. The transaminase levels give a day-by-day account of the amount of hepatocellular injury and death that occurs. Alkaline phosphatase levels estimate the amount of impedance of bile flow. The prothrombin time and serum albumin level are excellent gauges of hepatic protein synthetic ability, whereas the bilirubin level is probably the best test of overall liver function. Many tests are now available that permit one to diagnose specific diseases of the liver.

Alanine Transaminase↗

That demon rum.

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Alcoholism↗

Effect of amino acids and dipeptides on ethanol absorption across the rat intestine.

Effects of amino acids and dipeptides on ethanol (50 mM) absorption were studied by in vivo perfusion of the rat intestine. All the amino acids and dipeptides tested enhanced the rate of ethanol absorption over that observed with a control solution containing an equimolar concentration of mannitol. The increase in the rate of ethanol absorption can be related to the entry of ethanol with water which accompanies the active absorption of these nutrients. Some amino acids and dipeptides like lysine, tryptophan and glycyl-phenylalanine have an additional stimulatory effect on ethanol absorption which seems unrelated to water movement.

Amino Acids↗

Ethanol-induced hypertriglyceridemia. Prevalence and contributing factors.

Seventy-seven chronic alcoholic subjects admitted to two alcoholic detoxification centers were evaluated for lipid abnormalities. Nineteen (26%) of these male patients had serum triglyceride levels greater than 150 mg/100 ml and six (9%) had serum cholesterol levels greater than 250 mg/100 ml. Compared to 33 age-matched, nonalcoholic control subjects, there was a significantly greater incidence of hypertriglyceridemia in the alcoholic subjects. All patients with triglyceride abnormalities had type IV electrophoretic patterns. The triglyceride elevations were not related to serum amylase, lipase, liver function, obesity, and abnormal fasting glucose. We conclude that there is a significant increase in hypertriglyceridemia in chronic alcoholic patients.

Alcoholism↗