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Biomedical subjects

R Savini

Publications and source records attributed to R Savini.

At least 55 records · Page 3Linked to original sources
PubMed1976

Deformities of the spine in neurofibromatosis. Clinical and radiographic study of 46 cases.

Scoliosis, in particular kyphoscoliosis, is the most frequent bony abnormality in neurofibromatosis (up to 43 per cent). The most usually accepted aetiopathogenesis is a primary mesoblastic defect of the vertebrae, though other hypotheses exist. Hereditary factors have been shown to be present in about half the cases and the spinal deformity is almost always associated with skin changes, and less frequently with nerve or cardiac changes or with elefantiasis. The ages most affected are from four to eleven years, the commonest site is the dorsal spine and the average number of affected vertebrae is 5.5. There are three main radiological characteristics: widening of the spinal canal, widening of the intervertebral foraminae, and a scalloped appearance of the posterior borders of the vertebral bodies. From the point of view of prognisis the scoliosis is markedly progressive and difficult to control, even after bone maturity. In consequence, neurological symptoms frequently arise, usually as late complications.

Adult↗
PubMedDate not supplied

Pulsing electromagnetic fields (PEMFs) in spinal fusion: preliminary clinical results.

Pulsing electromagnetic fields (PEMFs) were used during the postoperative management of 31 patients submitted to lumbosacral posterolateral fusion (PLF). The fusions were stimulated with PEMFs during the first 2 of the 4 months of postoperative immobilization. Consolidation of PLF was obtained in 20 of the 31 patients after 2 months of stimulation, thus, healing time was cut in half. After 4 months, fusion was observed in 30 out of the 31 cases submitted to stimulation (96%).

Adult↗
PubMedDate not supplied

Powdered alumina implants in the experimental animal: a histological study conducted in the rat.

The authors present a histological study conducted in the rat after powdered alumina implantation in the subcutis, the muscle and the peritoneum. After two weeks the same intense acute inflammatory reaction was observed in all of the implantation sites. After eight weeks the inflammatory reaction had regressed: there was a thin layer of connective tissue around the implant, completely isolating it from the surrounding tissues.

Aluminum Oxide↗
PubMedDate not supplied

Fracture of the posterior arch of the atlas.

The authors analyzed the results obtained in 10 fractures of the posterior arch of the atlas treated nonsurgically. There was consolidation in all of the cases at the end of treatment. According to the authors the element which most characterizes this fracture is constituted by its radiological diagnosis which principally makes use of lateral projection. In particular cases, when patients are characterized by multiple trauma, the fracture may go unrecognized.

Adolescent↗
PubMedDate not supplied

Os odontoideum.

Between January 1981 and December 1985 at the Rizzoli Orthopaedic Institute 8 patients affected with atlo-axial instability secondary to os odontoideum were submitted to surgery: all of the patients were characterized by persistent cervical pain and neurological deficit, which was still at an initial stage in 5 cases, and more severe in the remaining 3 (severe spastic tetraparesis). All of the patients were submitted to a similar treatment protocol in three stages: 1) preoperative reduction in halo-plaster, 2) surgical stabilization of C1-C2 by posterior vertebral fusion (limited to C1-C2 in 6 cases and extended as far as the occiput in the remaining 2), 3) postoperative immobilization in halo-plaster for an average of 12 weeks. At follow-up obtained after an average of 4 years and 2 months there was consolidation of the fusion in all of the cases treated: in 1 case, however, revision of the fusion was required 3 and 1/2 months after surgery, whereupon fusion was finally obtained. The total regression of pain was obtained in all 8 of the cases treated and there was evident neurological recovery in the 3 patients who had been characterized by severe spastic tetraparesis prior to surgery. The treatment protocol used in this series of patients proved to be a reliable one. Thus, it was possible to avoid the onset of chronic atlo-axial instability and its severe neurological sequelae in those cases where neurological deficit was still at an initial stage; furthermore, effective recovery was obtained in patients in whom neurological deficit was severe.

Adolescent↗
PubMedDate not supplied

The nonsurgical treatment of fractures of the dens epistrophei.

The authors examined 25 fractures of the dens epistrophei treated conservatively by several methods in order to evaluate the most suitable treatment for this lesion. A Minerva plaster cast proved to be effective in the treatment of type III fractures, while the halo plaster system obtained the best results in type II fractures.

Adolescent↗
PubMedDate not supplied

Medullary compression secondary to acute post-traumatic cervical disc herniation: 5 cases.

Based on their observation of 5 cases of acute posttraumatic cervical disc herniation with medullary lesion, as well as on what is reported in the literature, the authors examine the clinical features of the disease, at the same time evaluating and comparing the major diagnostic studies. What emerges from the study is the importance of NMR and CAT in the diagnosis of the lesion. Finally, the authors emphasize the importance of early surgical treatment.

Adult↗