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Biomedical subjects

R Savage

Publications and source records attributed to R Savage.

66 records · Page 4Linked to original sources
PubMed1985

In vitro studies of a new method of flexor tendon repair.

The mechanical factors in tendon repair have been studied and physical principles applied to this unsolved problem. A new technique of tendon repair has been derived and tested in the laboratory. Compared to several well known techniques it has been shown to have three times the tensile strength and to allow one tenth the gap to form between the tendon ends under load. It has been designed not to constrict the blood supply of the tendon and the tests indicate that it will be strong enough to allow early active mobilisation even after inflammation has caused the tendon to soften.

Animals↗
PubMed1984

Violence.

Explore the source record for details and available documents.

Family Practice↗
PubMed1984

Detection of ischemic wall dysfunction: comparison between M-mode echocardiography and sonomicrometry.

The quantification of regional ventricular function by M-mode echocardiography was compared to that by sonomicrometry in 10 closed-chest, sedated swine during temporary occlusions of the left circumflex coronary artery. Wall thickening during systole (%WT) was calculated to quantitate regional myocardial function, and percentage of fractional shortening (%FS) was calculated from both sonomicrometer tracings and M-mode echocardiograms. Ventricular dimensions at end diastole and end systole were also compared before and after 2 minutes of coronary artery occlusion. Both techniques detected significant changes in wall thickness, %WT, and %FS after occlusion. Changes in %WT during coronary artery occlusion detected by M-mode echocardiography and sonomicrometry had a significant linear relationship (p less than 0.05). Discrepancy between the two techniques in the measurement of wall thickness at end diastole was attributed to the difficulty in measuring relatively small distances with M-mode echocardiograms. However, we conclude that the clinical M-mode echocardiogram is capable of detecting acute regional wall dysfunction associated with ischemia.

Animals↗
PubMed1980

Popliteal artery injury associated with knee dislocation: improved outlook?

Popliteal artery injury due to knee dislocation is an injury complex that is being reported with increasing frequency. A review of the literature from 1974 to 1978 reveals 40 new cases. Of these cases, 85 per cent underwent successful arterial repair, an encouraging figure. although few, large individual series exist, it is felt that an improved prognosis may be expected. Four case reports from the last year at the author's institution are presented. Various aspects of diagnosis and treatment are analyzed and recommended.

Adolescent↗
PubMed1977

Alterations of fast axoplasmic transport in experimental methyl n-butyl ketone neuropathy.

Methyl n-butyl ketone (MBK) is known to produce a giant axonal neuropathy in man and experimental animals characterized pathologically by a gradual increase in the number of neurofilaments which become associated with focal areas of axonal swelling and thinning of the myelin sheath. Fast axoplasmic transport was studied in rats exposed to MBK. In 10 severely paralyzed rats exposed to MBK there was a significant impediment of fast axoplasmic transport following dorsal root ganglion injections (x +/- S.D. = 283.2 +/- 20.34 mm/day) compared to normal controls (417.6 +/- 23.78 mm/day). In rats undergoing injections into the ventral horn of the spinal cord there was a gradual impairment of the mean down flow rate for transport of [3H]leucine which correlated with the severity of the MBK induced neuropathy. Quantitative morphological determinations showed that the total number of neurotubules per unit cross-sectional myelin area and the number of neurotubules associated with mitochondria in swollen axons was unchanged from normal. The total number of mitochondria in randomly sampled axons varied significantly from controls but the absolute number of mitochondria associated with neurotubules was unchanged from normal. The results of these studies suggest that the impediment of fast axoplasmic transport may be related to the increased neurofilaments producing focal areas of axonal blockage.

Animals↗
PubMed1977

Doctors' attitudes to women in medicine.

There is only moderate enthusiasm in the medical profession for an increase in the number of women doctors. The profession has been slow to recognize the problems of combining home life with a career, but it is encouraging that there appears to be little discrimination against women.Women doctors are capable of and may wish to rise to the intellectual challenges of full-time medicine. Unfortunately, too often the attempt at combining domestic life with a professional career is poorly organized and minimally supported leading to an unsatisfactory compromise. Until a more positive attitude develops within the profession women doctors will not feel accepted as equals.

Attitude of Health Personnel↗
PubMedDate not supplied

Getting into the act: a Canadian nurse's experience.

The Canada Health Act became law in April 1984 after years of debate and negotiations. The Canadian Nurse's Association (CNA) with a membership of 169,000 took a leading role in the lobby to influence that act, the guiding legislation for Canada's national health insurance system. The CNA lobbied for changes in the Canada Health Act that implied fundamental reforms in the health care delivery system. This paper will chronicle the political activity of CNA and its twelve member associations as they sought to influence the design of the new legislation.

Canada↗