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Biomedical subjects

R Sarrazin

Publications and source records attributed to R Sarrazin.

88 records · Page 5Linked to original sources
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[Mediastinal lymph node extension in primary bronchial cancer: correlation of x-ray computed tomography, magnetic resonance imaging and mediastinoscopy. Apropos of 50 cases].

Based on a homogeneous series of 50 cases investigated within less than a week by CT scan and NMR imaging with mediastinoscopic correlation, and in 32 of theses cases with correlation with operative findings, a critical study was carried out of modern imaging methods for detection of mediastinal gland invasion from primary bronchial cancer. Axial mediastinoscopy presented absolute specificity and very high sensitivity (93%) markedly superior to those of CT scan and NMR imaging. The two latter examinations were practically of equal efficacy: sensitivity of NMR (80%) was somewhat higher than that of CT scan (70%) whereas specificity of CT scan was 83% as against 70% for NMR. Lack of efficacy of axial mediastinoscopy was in cases with extra-axial lymphatic extension (anterior mediastinal chains) from primary cancer. These results suggest that, in view of current inconveniences of NMR imaging, the best means for local and regional exploration of primary bronchial cancer preoperatively is combined CT scan and mediastinoscopy. The diagnosis of glandular enlargement of anterior mediastinal lymphatic chains should lead to performance of an anterolateral mediastinoscopy.

Aged↗
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[Computed tomography of the mediastinum: normal anatomy and non pathologic variations in the adult (author's transl)].

This work is based on the separate study of a triple material: axial gross body sections from cadavers (4); normal and conventional radiographs with or without opacification; in vivo scans (210). Authors have selectionned thriteen scans patterns according to several regional levels: supra-aortic scans (n08 1, 2, 3); scan through the horizontal part of aortic arch (n0 4B); the scan of the aorto-pulmonary window (n0 4B); supra-cardiac scans through intra and extra-pericardic parts of great vessels: vena cava, aorta and pulmonary artery (n08 5, 6, 7); heart and cardiac cavities scans (n08 8, 9, 10, 11); scan through the retro-crural space (n0 12). Knowing these regional scan patterns, makes it possible to the radiologist to manage a topographic approach quite adapted to the technical mode of direct scannography through the area of interest, already tested by some constructors. The non pathologic variations are numerous. Mediastinal lipomatosis, dilated and tortuous great vessels in the older and atheromatic individual, constitutional variations of the vessels topography. Limits found out during this work concern heart examination and hilum study; great strides are to be achieved in these fields because of the unceasing technical improvments.

Adult↗
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[Benign hypoglycemiant pleural tumors. Report on two cases].

Two cases of hypoglycemiant pleural fibroma are reported: -- the first case, in a patient with sarcoidosis, was diagnosed following the onset of neuropsychic manifestations due to hypoglycemia; --the second case, much more atypical, was a patient with an enormous pleural tumor affecting cardiorespiratory function to such a degree that almost total incapacity ensued: the hypoglycemia was detected during routine pre-operative investigations. Various extrathoracic manifestations accompany these tumors: osteo-articular (present in 1 patient), and thyroidal (present in both cases). The various mechanisms proposed to explain the development of hypoglycemia in patients with certain extra-pancreatic tumors are reviewed.

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