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Biomedical subjects

R Sandyk

Publications and source records attributed to R Sandyk.

At least 505 records · Page 28Linked to original sources
PubMed1981

Somatosensory feedback mechanisms in tongue and speech muscle movements.

The silent period of the tongue muscles was examined in two groups of 3 patients after operation upon the two main somatosensory pathways of the tongue in order to find out whether the servocontrol theory is also applicable to tongue and speech movements. The silent period was found to be in the normal range in the first group of patients (group I) who underwent surgery to the three upper cervical roots and was not detectable in the second group of patients (group II) who had undergone surgery to both trigeminal nerves. None of the patients in group I had any postoperative alteration of articulation or of the non-articulatory tongue movements, whereas the patients in group II showed a marked orolingual ataxia without disturbance in articulation. These results imply that the servocontrol theory is not completely applicable to the tongue movements and that the speech organ operates independently from a feedback control of the muscle spindles of the tongue. The speech process seems to be preprogrammed.

Electromyography↗
PubMed1981

Congenital fibre type disproportion. A case report.

A case of congenital myopathy (fibre type disproportion) in a 14-year-old White girl is described. She was born a 'floppy baby' and her developmental milestones were delayed. A congenital muscle dystrophy was suspected clinically and a quadriceps biopsy examination revealed congenital fibre type disproportion.

Adolescent↗
PubMed1981

Adult neuronal ceroid lipofuscinosis (Kufs' disease). A sporadic case.

A sporadic case of neuronal ceroid lipofuscinosis (Kufs' disease) in a 29-year-old man is reported. At onset the disease resembled schizophrenia (thought disorder, flat affect, paranoia, hallucinations and inappropriate behaviour), but after the appearance of associated neurological symptoms such as myoclonic jerks, cerebellar ataxia, rigidity and involuntary movements a neurological disorder was suspected. Cortical biopsy established the diagnosis.

Adult↗
PubMed1981

Late detection of cerebral glioma causing seizures in childhood. A case report.

Late detection of a cerebral glioma causing convulsions in a 7-year-old girl is reported. Her neurological status was normal but her behaviour deteriorated progressively and her seizures became more frequent and resistant to therapy during the 11/2 years after her first admission to hospital. Computed tomography revealed a zone of low density in the right parietal area which was considered to be due to a cerebrovascular accident affecting the middle cerebral artery. Although it is generally considered that epilepsy beginning in infancy or childhood, even if focal, is only rarely associated with neoplasm, epilepsy which is resistant to treatment and progressive change in a child's behaviour should suggest the possibility of a cerebral neoplasm and further invasive investigations should be performed.

Brain Neoplasms↗
PubMed1981

Voluntary responses to peripheral stimulation in Parkinson's disease. An electrophysiological study.

Voluntary motor responses of 15 patients with Parkinson's disease and 5 normal subjects in the same age group were examined electromyographically. The reaction time (RT) (period of latency) and the successive reaction (SR) time (between two quick repetitive voluntary movements) of the facial, eye and masseter muscles following electrical stimulation from the periphery (thenar muscles) were measured. In the patients the RT and SR time following peripheral stimulation were obviously delayed. These results suggest that cortical motor areas are involved in Parkinson's disease so that, following peripheral stimulation, cortical activity is inhibited for a relatively long time. This occurs most often following two brisk repetitive voluntary muscle movements (SR).

Aged↗
PubMed1981

Choreo-athetosis induced by phenytoin in an epileptic child. A case report.

A 5-year-old child with epilepsy and underlying brain damage developed choreo-athetosis during intoxication with phenytoin. Drug intoxication was suggested by the dose the child was taking (75 mg 3 times a day) and confirmed by measuring the serum phenytoin concentration which was 229 mmol/l (therapeutic range 40-80 mmol/l). The choreoathetoid movements ceased 4 weeks after discontinuation of the drug, although the blood level returned to the therapeutic range after 2 weeks.

Athetosis↗
PubMed1981

Acute deterioration and death in infancy due to posterior fossa tumour. A case report.

Acute deterioration of a 27-day-old male baby born at term is reported. On admission the baby presented with acute gastro-enteritis which had developed 3 days previously. Apart from enlargement of the head, no signs of CNS dysfunction could be elicited. Only after acute clinical deterioration was a suspicion of a cerebral process aroused. Computed tomography showed a posterior fossa mass and postmortem examination revealed a cerebellar medulloblastoma which was probably of antenatal onset.

Cerebellar Neoplasms↗
PubMedDate not supplied

Phenobarbital-induced Tourette-like symptoms.

A 7-year-old child with spastic cerebral palsy and a seizure disorder developed Tourette-like symptoms during therapy with phenobarbital. These symptoms occurred while phenobarbital blood levels were in the therapeutic range. Known causes of movement disorders were eliminated after evaluation. On repeat challenge with phenobarbital, the symptoms recurred. Phenobarbital should be added to the list of drugs that cause Tourette-like symptoms.

Cerebral Palsy↗
PubMedDate not supplied

Tourette syndrome.

Explore the source record for details and available documents.

Child↗