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Biomedical subjects

R Sandberg

Publications and source records attributed to R Sandberg.

15 recordsLinked to original sources

Reconstruction of the anterior cruciate ligament. A 5-year follow-up of 89 patients.

In all, 112 consecutive patients were operated on because of chronic insufficiency of the anterior cruciate ligament. The surgical procedure used was an intraarticular reconstruction using the medial third of the patellar ligament. Eighty-nine patients were reexamined 5 (2-11) years after the reconstruction. Eighty percent of the patients were satisfied, but most of them had discontinued strenuous sports. The best results were observed in individuals with normal demands on their knee function.

Adolescent

Operative versus non-operative treatment of recent injuries to the ligaments of the knee. A prospective randomized study.

Two hundred consecutively seen patients who had an injury to either the anterior cruciate ligament or the medial collateral ligament, or both, were randomly allocated to treatment by either conservative or a surgical regimen. Injuries to the medial collateral ligament could not be demonstrated to benefit from surgical treatment in any respect--with or without surgery the results were excellent. With injuries to the anterior cruciate ligament, recovery was more rapid without surgery but otherwise the results differed between the groups in only one respect: the pivot-shift test was more often positive after conservative treatment. The results were good in both treatment groups even though most of the patients who had an injury of the anterior cruciate ligament were somewhat less pleased with the outcome after a period of time.

Adolescent

Partial rupture of the anterior cruciate ligament. Natural course.

A prospective study was done of 29 patients with conservatively treated partial ruptures of the anterior cruciate ligament that were stable at the initial examination under anesthesia. The ruptures were reevaluated for stability and knee function from 12 to 60 months after injury. Many had developed signs of instability. The forward drawer sign (Lachman test) and the pivot shift tests were positive. There was also measurable sagittal instability (anterior drawer sign). In every case, knee function was almost completely restored.

Athletic Injuries

Stability tests in knee ligament injuries.

For 182 knee joints with ligamentous injuries confirmed at surgery the records contained a complete and documented stability examination. In anterior cruciate ligament injuries the Lachman test and the anterior drawer sign were of similar value with regard to the frequency of false negatives - they missed half of the injuries - but their accuracy improved when they were repeated under anesthesia. The pivot shift was useful only under anesthesia. The medial collateral ligament injuries were usually detected because of valgus instability, also without anesthesia. The stability tests done with the patient under anesthesia are sufficiently reliable for making decisions about knee ligament surgery.

Adolescent

Traumatic hemarthrosis in stable knees.

A thorough arthroscopic examination was performed in 90 consecutive patients with sprained knee injuries with hemarthrosis, but without signs of instability or fracture. The source of bleeding was found in all but five joints. Thirty-nine injuries were tears of the cruciate ligament, only three of which were complete tears. Fourteen injuries were (osteo)chondral fractures and six were meniscal lesions. The remainder bled from the synovium or meniscal attachments. The arthroscopic examination resulted in an altered course of treatment in few, if any, of these patients.

Adolescent

Penetration enhancers and other factors governing percutaneous local anaesthesia with lidocaine.

The percutaneous penetration of the local anaestetic lidocaine was investigated in the guinea-pig. Three different types of composition were employed: lidocaine hydrochloride in aqueous solution, lidocaine base in an aqueous alcoholic solvent mixture and lidocaine base in aqueous solutions of dipolar aprotic solvents. The latter solvents included simple tertiary aliphatic amides, amides related to dimethylacetamide, some cyclic amides as well as a number of miscellaneous compounds. The degree of dermal anaesthesia was noted in each case. In addition, the uptake and distribution of lidocaine in the skin and its absorption into the blood were studied using tritium-labelled drug. The results show that the percutaneous penetration of lidocaine is dependent on the concentration of the agent, the time of epicutaneous application of the composition, whether the agent was used as salt or free base, and the nature of the solvent medium. Lidocaine base in aqueous dimethylacetamide was most effective in producing percutaneous local anaesthesia.

Amides