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Biomedical subjects

R Salamon

Publications and source records attributed to R Salamon.

At least 145 records · Page 8Linked to original sources

Prognosis in juvenile dermatopolymyositis: a cooperative retrospective study of 70 cases.

A retrospective multicenter study was conducted with 70 patients with juvenile dermatopolymyositis. Among survivors with sufficient follow-up (at least two years), a good prognosis subgroup was characterized by significantly better (P less than 0.001) initial response to steroids and less frequent pharyngeal involvement when compared to other patients in a poor prognosis subgroup with significant sequelae or still active disease. Patients who died had more severe pharyngeal involvement than those who survived (P less than 0.05).

Adolescent↗

[Has prenatal ultrasonic diagnosis modified the prognosis of intestinal atresia? Results of a multicenter study].

A multicentric investigation concerning intestinal atresia diagnosed in french university hospitals from 1979 to 1983, has been done. Out of 96 exploitable cases coming from 8 centers, 28 correspond to intestinal atresias which had subject to prenatal echographic diagnosis: that is 29%. 15 of the 96 atresias were affected with trisomy. 21 which had not been recognised in utero. Concerning the isolated duodenal atresia, not accompanied by any other malformation, the post surgical evolution has been appreciated during the 12 months following the surgical operation. There was no statistically significant difference, in favour of the group of children whose malformation has been recognised in utero, concerning the number of post surgical complications. This result, apparently deceitful, can be explained by the early management of these malformations in specialised centers which have participated in this study.

Down Syndrome↗

[Incidence of cancer in Martinique 1981-1982].

A systematic registration of morbidity from cancers was started in 1981 and 1982 in the french department of Martinique. In the course of two years 1081 new cases of cancers were recorded for a population of 320 000. The survey gives information on topography, differences for sex and ages. The morbidity survey allows comparison with the incidence rate of cancers in other departments of France or other countries.

Female↗

[Exploratory strategy for hydrocephalus in adults].

Decision theory can be useful for the determination of an optimal diagnostic and/or therapeutic strategy. Of course, the physician remains the only decision-maker, but these methods, quite simple, introduce a scientific background to medical decisions by the quantitative evaluation of the consequences of the choices. We will present the use of such a methodology in the treatment of adults presenting hydrocephalus.

Adult↗

A statistical method for the estimation of neuronal response latency and its functional interpretation.

The functional role of many central nervous structures has been inferred from the temporal relationship of a neuronal response with the different sensory and motor events in an experimental design such as when an animal performs a trained movement in response to a conditioned stimulus. However, this kind of data analysis leads to problems in estimating the occurrence and latency of any neuronal response. We examine these problems and propose a novel technique of data analysis to estimate the point of change in a sequence of neuronal discharge. Furthermore, data can be tested to see whether the neuronal response is related to the conditioned stimulus or the motor act. The method can also be used in the simple situation of determining the latency of a neuronal response after a stimulus.

Animals↗

Deconvolution analysis of radionuclide angiocardiography curves: problems arising from fragmented bolus injections.

Deconvolution analysis of radionuclide angiocardiography time-activity curves (TAC) in the cases of fragmented bolus injections was studied by using a new deconvolution technique based on the maximum a posteriori estimator. This method was first tested by simulation studies which showed its capability for accurate handling of deconvolution both for single and double peak input functions. These simulations have proved this technique to have advantages over a Fourier transform division method used with a low-pass filter. In patient studies, deconvolution of pulmonary TAC by superior vena caval TAC produced poor results in double peak (fragmented) bolus injections, compared with single peak bolus injections (SPBI). This discrepancy seems to be due to the fact that the postulates of linearity and invariance, on which deconvolution analysis is based, do not hold for the 'cardiopulmonary system' which extends from the superior vena cava to the lung. The differences between the model and the real system appear unimportant for SPBI. However, differences become apparent for fragmented bolus injections. Deconvolution analysis should be avoided with this type of input function in this cardiopulmonary system.

Aged↗

[Prevalence of migraine in a working population group in the Aquitaine region. Methodology and results (author's transl)].

To our knowledge, no study of prevalence of migraine has ever been carried out in France. Since this is a well defined disease with precise diagnosis and therapy, it was possible for us to carry out a survey on a large population. We therefore had to build an automatic process if migraine diagnosis using simple computerized questionnaires. The results presented are these relative to a survey carried out on a working population group of about 3,000 persons. These were interviewed during the annual medical examination which workers in France have to undergo. The socio-economic consequences of migraine could thus be studied.

Adolescent↗

Diagnostic aids.

In clinical oncology, the decisional problems encountered are rarely problems of diagnosis, and this article may appear out of place in the present framework. Its aim, however, is twofold: i) to present the potential contribution of data processing techniques to the whole diagnostic process; ii) to define a few methodological aspects which, while useful in assisting diagnosis, can be transposed to other decisional aspects (determination of prognosis, aids to therapy, optimalization of investigation strategies) more frequently met in clinical oncology, as will be shown in the numerous articles presented here. This methodology is first and foremost an apprenticeship in reasoning, in self-interrogation, and in the formulation of problems.

Decision Making↗

[Classical special investigations in hospital neurology. Evaluation of their diagnostic contribution (author's transl)].

A quantitative analysis of the diagnostic contribution of the classical special investigation normally used in hospital neurology. Six examinations were studied: laboratory blood investigations, electroencephalogramm, lumbar puncture, optic fundus, standard skull X-ray, standard spine X-ray. The analysis involved 548 patients in whom 2219 examinations were performed with a yield of 26 "corrected" diagnosis (a diagnosis in which there was a clinical error corrected in the light of the results of these examinations).

Bayes Theorem↗