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Biomedical subjects

R Sailer

Publications and source records attributed to R Sailer.

At least 73 records · Page 4Linked to original sources

[The post-operative recurrent laryngeal nerve paralysis and its course (author's transl)].

Benign diseases of the thyroid may also be the cause of pre-operative paralysis of the recurrent laryngeal nerves. the frequency of palsies in uncomplicated strumectomies is approximately 4 to 5%. A markedly higher risk exists in endothoracic goitres which must be delivered by thoracotomy, in recurrencies and thyroiditis. Dissection, crush lesions, strain and nerves mistakenly pulled into a ligature are the most frequent causes of injury; haematoma, oedema, heat by diathermy, lesions caused by a scar and a neuritis of the nerve are less common. 30 to 50% of unilateral laryngeal nerve palsies are without symptoms. An exact examination, however, reveals some alterations of the voice. A logopedic treatment combined with electro-therapy accelerates the compensation of the intact vocal cord. In bilateral paralysis of the recurrent laryngeal nerves a tracheotomy is necessary because of respiratory distress. After 6 to 9 months a glottis-widening procedure may be performed since no further recovery can be expected. A unilateral paralysis has a recovery rate of 40%; therefore in 2 to 3% of uncomplicated strumectomies a definite paralysis of the recurrent laryngeal nerve is observed.

Glottis↗

[Incidence of recurrent nerve palsy after strumectomy. Long term results (author's transl)].

During the last years all 1713 patients which for different causes underwent strumectomy were controlled by the laryngologist before and after the operation. In 147 cases an unilateral recurrent nerve palsy resulted, in 22 patients both vocal cords were paralysed. Out of these 169 patients we could follow up 63 patients, which were examined after one year. In 28 patients with postoperatively complete paresis of one vocal cord 23 showed recovery and normal function while in two patients a markedly reduced motility was present. Out of the 22 cases which postoperatively had both recurrent nerves injured 10 could be checked one year later. In three patients any vocal cord movement was still absent, in three patients one vocal cord showed normal function again and only in one case both vocal cords revealed normal physiological mobility. Three other patients demonstrated a reduced but market mobility of one vocal cord. The results are discussed in relation to the clinical and histological datas.

Follow-Up Studies↗

[Blood coagulation disorder in islet cell adenoma].

Coagulation physiologic tests were carried out and plasminogen activity and concentration were measured in the case of 6 patients (5 islet cell adenomas and 1 islet cell carcinoma). Except a reduced plasminogen activity in the postoperative phase no other unequivocally pathologic data were found. This phenomenon can probably by attributed to the enhanced plasmin inhibitors of the human plasma. The problem of so-called hypercoagulaemia of these patients can be clarified only after the investigation of the half-lives of the various coagulation factors.

Adenoma↗

[Myositis ossificans following head injury (author's transl)].

This is a report on 14 patients with myositis ossificans with simultaneous head injury. Predilected sites are the hip and elbow joints as well as thigh musculature, where particularly in the youthful and younger adults ossifications occur 5--8 weeks after the accident. Premature operative treatment is useless because of the danger of recurrence. The process of ossification usually comes to a standstill 8--12 weeks following the trauma. The diagnosis is made on the basis of clinical examination (hardening of muscles, immobility of joints) and X-ray pictures. The pathogenesis and modes of therapy are discussed in detail. Furthermore, the incidence of this complication of head injury in various age groups is evaluated statistically.

Adolescent↗

[Hyperbaric oxygen treatment in gas gangrene (author's transl)].

Among 100 patients with proven gas gangrene surgical treatment was undertaken in 34 who also received 30--60 mega-units of penicillin, in addition to appropriate shock treatment. Since 1967, additional treatment in a hyperbaric chamber was undertaken in 66 patients. There was no clear-cut advantage of hyperbaric oxygenation as far as the death-rate was concerned. There was merely a moderate decrease in the amputation rate after limb injuries. Wide incision of the wound and radical surgical excision of all tissue affected by gas gangrene continues to be an essential form of treatment.

Amputation, Surgical↗

[Clinically undiagnosed glycogen storage disease type I as cause of postoperative death (author's transl)].

A 30-year-old patient was admitted to hospital for cholecystectomy with a diagnosis of complete obstruction of the cystic duct. The preoperative clinical and chemical findings were normal. Following cholecystectomy the patient recovered normally from the anaesthetic. Three hours later sudden cardiac arrest occurred. Necropsy revealed glycogen storage disease type I. Hypoglycaemia and metabolic acidosis had probably led to hypokalaemia which is considered as the cause of cardiac failure.

Adult↗

[Experience in the treatment of islet adenomas (author's transl)].

The clinical picture of insulinomas is discussed with reference to the literature and 27 of our own cases. The neurological symptoms are usually more prominent, so that the diagnosis is delayed. The average delay between the onset of the disease and its recognition was 4 years. Whipple's triad is characteristic of insulinoma. Of the chemical laboratory investigations, the hunger and tolbutamide tests are the most reliable for the diagnosis. Because of the danger of brain damage, there is an absolute indication for operation. Conservative treatment is burdened with numerous side effects so that it is only considered as a temporary measure or for inoperable patients. In the overwhelming majority of cases, enucleation of the tumors from the pancreas is successful. The cure rate after successful operation is about 80%.

Adenoma, Islet Cell↗

[Problems of the one- or two-stage operations of carcinoma on the left part of the colon (author's transl)].

260 radically operations of carcinoma of the colon were carried out from 1963-1972; 163 of these operations have been done on the left part of the colon. The results of the one- and two-stage procedures were compared with the related literature. 46.5 per cent of the resected lymphnodes were affected by carcinoma. An expanded resection was done in 24 cases complicated with tumour perforation in adjacent organs. Among 147 one-stage left-side resections 20 insufficiencies of the anastomoses (13.5 per cent) were observed. To protect the anastomoses in 8 cases a coecal fistula and in 4 cases a fistula of the transverse colon were performed. There was no insufficiency of the anastomose. In 4 cases of two-stage precedures insufficiencies of the anastomose were found at the extraperitoneal replaced anus. The mortality was found to be 11.6 per cent. Peritonitis occurred in 18 cases: after 6 right sited and 12 left sited resections.

Adolescent↗