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Biomedical subjects

R Sadovsky

Publications and source records attributed to R Sadovsky.

26 records · Page 2Linked to original sources

Diagnosis and management of systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is not a rare disease. There are several common clinical signs which should alert the physician to a possible diagnosis of SLE and which should condition him to look for specific clinical and laboratory findings. In addition to simple screening tests, useful procedures include a search for antinuclear antibodies, lupus erythematosus (LE) cells, anti-DNA antibodies and low serum complement. Management is determined by the type of course encountered but most patients will do well under the care of their family physician.

Adult↗

Angioimmunoblastic lymphadenopathy: common symptoms, uncommon diagnosis.

After five months of treatment for what was believed to be tuberculosis, a 49-year-old woman had recurrence of high spiking fever, lymphadenopathy, and malaise along with an intermittent maculopapular rash. Other findings were a positive Coombs test, iron deficiency, elevated gamma globulin levels, polyclonal gammopathy, and hepatosplenomegaly. Biopsy of a cervical lymph node revealed an angioblastic pattern consistent with angioimmunoblastic lymphadenopathy. Review of biopsy material obtained six months previously showed the same changes. Antituberculosis therapy was discontinued, and a regimen of prednisone and iron replacement was begun. The patient did well initially; when symptoms returned, they were controlled by adding azathioprine to the regimen for steroid-sparing effect. However, serologic abnormalities returned and within a few months, symptoms exacerbated; despite intensive medical therapy, the patient died. Angioimmunoblastic lymphadenopathy is a recently recognized disorder with a usually progressive course. No treatment has yet been established as effective, and death usually occurs within one year after diagnosis.

Diagnosis, Differential↗

Sarcoidosis of the liver: evaluation with multiple imaging modalities.

Although sarcoidosis of the liver is common pathologically, imaging findings are extremely rare, because the noncaseating granulomas are usually not macroscopic and thus do not produce focal abnormalities. We present 2 cases of liver sarcoidosis with focal findings on computed tomography, magnetic resonance imaging, nuclear scanning, and ultrasonography. Imaging characteristics, which may facilitate making the diagnosis, are presented.

Adult↗

Oral health care issues in HIV disease: developing a core curriculum for primary care physicians.

BACKGROUND: Given the high occurrence of oral manifestations in patients infected with human immunodeficiency virus (HIV), the relative ease in recognizing these manifestations on physical examination, and their potential impact on the health care and quality of life in these patients, it is critical to provide adequate training for primary care physicians in this area. METHODS: Based on a review of the published literature and the consensus of a national panel of primary care physicians and dentists with clinical and research expertise in this area, a core curriculum was developed for primary care physicians regarding oral health care issues in HIV disease. RESULTS AND CONCLUSIONS: We describe the process of developing the core curriculum of knowledge, skills, and attitudes regarding oral health care issues in HIV disease. The final curriculum is in a format that allows for easy accessibility and is organized in a manner that is clinically relevant for primary care physicians.

Clinical Competence↗

Structuring a home visit program for residents.

Home assessment visits in which a family practice resident accompanied by a social worker and a specially trained nurse go to a patient's home have been a part of the curriculum for three years. A specific format has been developed for these visits. The trainees' initial positive views about home assessment visits were maintained after the visits with improved understanding of the impact of environmental, familial, and social factors on patient health. The efforts and effects of the nonphysician health care providers in home visits were clarified. Clearly, residents can appreciate and benefit from a well-structured home visit program.

Attitude of Health Personnel↗