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Biomedical subjects

R S Walker

Publications and source records attributed to R S Walker.

25 records · Page 2Linked to original sources

Hyperlactataemia in phenformin-treated diabetics.

Raised fasting blood lactate levels were observed in diabetic patients on phenformin in therapeutic dosage. After an intravenous glucose load this effect was exaggerated and the lactate/pyruvate ratio increased. Withdrawal of the drug led to normal blood lactate levels and a fall in the lactate/pyruvate ratio.

Adult↗