Search PubMed⌕ Search

Biomedical subjects

R S Thompson

Publications and source records attributed to R S Thompson.

At least 55 records · Page 3Linked to original sources
PubMed1998

Cancer screening in HMOs: program development and evaluation.

INTRODUCTION: In many clinical settings, effective cancer control is hampered by barriers related to the acute-care orientation of most medical practices. These include: prioritization of medical problems on the basis of urgency; a problem-oriented medical record that provides no ongoing documentation mechanism for cancer screening; conflicting guidelines; and no method for identifying and targeting persons who are eligible for screening. In contrast, HMOs are uniquely suited to deliver effective cancer control as they have already established many of the linkages required for successful primary and secondary prevention. METHODS: This paper describes the principles of a population-based approach to cancer prevention and draws on the experience of Group Health Cooperative of Puget Sound, an HMO in western Washington with more than 20 years' experience in prevention and centralized cancer screening. Methods for selecting and determining priorities among cancer prevention issues, components of successful screening programs, and measures of short- and long-term evaluation are discussed through examples of screening for breast, prostate, cervix, and colorectal cancers. CONCLUSIONS: HMOs have provided leadership in the integration of health services and the promotion of continuity of care. Using a population-based approach, cancer prevention programs may be supported by existing automated information services to reduce morbidity and mortality through early detection.

Community Health Planning↗
PubMed1998

Epidemiology of diarrheal disease among children enrolled in four West Coast health maintenance organizations. Vaccine Safety Datalink Team.

BACKGROUND: We used information from the Vaccine Safety Datalink (VSD) about approximately 1 million children enrolled in four health maintenance organizations to assess the morbidity from diarrhea and estimate the disease burden of rotavirus. METHODS: We examined trends of diarrhea-associated hospitalizations and emergency room (ER) visits among VSD children ages 1 month through 4 years during October, 1992, through September, 1994 (two rotavirus seasons) and estimated the morbidity from rotavirus on the basis of characteristic patterns of age and seasonality. RESULTS: Overall diarrhea was associated with 6.3% of hospitalizations and 4% of ER visits. During a child's first 5 years of life, we estimated that 1 in 57 was hospitalized and 1 in 21 required an ER visit because of diarrhea. Each year the number of diarrhea-associated hospitalizations and ER visits was greatest in winter among children ages 4 to 23 months and peaked in November in California and during February in Oregon and Washington. The winter seasonality of diarrhea-associated hospitalizations reflected the trends for diarrhea of presumed noninfectious and viral etiologies, which together accounted for most (92.9%) hospitalizations. CONCLUSIONS: Diarrhea is an important cause of morbidity among VSD children. The epidemiologic patterns of diarrhea-associated hospitalizations and ER visits resembled those reported previously for rotavirus diarrhea, suggesting that rotavirus may be a major contributor to the overall morbidity from diarrhea. Enhanced surveillance by screening for rotavirus in a sample of children with diarrhea will permit a more accurate assessment of the disease burden of this pathogen and the cost effectiveness of a rotavirus immunization program.

California↗
PubMed1998

Improving community-based prevention by transforming managed care organizations into health improvement organizations.

Large nongovernmental health systems are taking over much of the direct delivery of healthcare to populations previously served by health departments. This article explores ways in which governmental and academic public health systems can help maximize positive effects of this trend on community health. The experience of Group Health Cooperative of Puget Sound is reviewed, with particular attention to its prevention structure and work to address tobacco use. An ideal preventive health improvement system model is presented, and future directions and key lessons are explored.

Delivery of Health Care↗
PubMed1998

Prevention of bicycle-related injuries: helmets, education, and legislation.

Efforts to reduce the toll of bicycle-related head injuries illustrate how the basic public health principles of surveillance, epidemiologic study, intervention, and evaluation can have a substantial impact on an injury problem, using a variety of injury-prevention strategies. Head injuries are the leading cause of serious morbidity and mortality from bicycle crashes. Helmets have been shown to reduce bicycle-related head injuries for cyclists of all ages involved in all types of crashes including those with motor vehicles. Helmet use has been promoted using educational campaigns, helmet subsidies, and legislation. Careful evaluation of these strategies has shown that these interventions increase helmet use and decrease the incidence of bicycle injuries. The model developed for the prevention of bicycle injuries is widely applicable to other injury problems.

Age Factors↗
PubMed1998

A training program to improve domestic violence identification and management in primary care: preliminary results.

Domestic violence as encountered in day-to-day practice is greatly underidentified. It is estimated that only 3% of cases are presently being identified, and practitioners are uncertain of what to do if a case is discovered. In this paper, a training program to improve identification and management of domestic violence (DV) in primary care and the providers' responses to the program are described. A multimodal training program was undertaken to demonstrate and practice the incorporation of didactic content into practice for the health care teams. Two medical centers from a large staff-model HMO were chosen at random from five volunteering for training. The entire adult health care medical center teams, including physicians, physician assistants, RNs, LPNs, medical assistants, and receptionists, were the recipients of the training. Assessment of provider valuation of the components of the training program was performed by administering a standardized 5-point Likert-scaled questionnaire 9 months after the training. This time interval was chosen because we were interested in lasting program effects. Core didactic content, such as the epidemiology of DV, identification and management of victims and batterers, and legal issues, was highly rated. Delivery of the content through role-playing, start-stop videos and presentations by former victims received lesser but solid support. Follow-up assessment 9 months post training demonstrates solid support for many components of the program: highest for specific information content areas, but strong for techniques and processes. The training program appears to be a promising method to improve provider skills in DV management.

Adult↗
PubMed1997

Damage to bicycle helmets involved with crashes.

The objective was to evaluate the relationship between helmet damage and head injuries in helmeted bicyclists in a sub-study of a large case-control study of bicycle injuries and helmet effectiveness. The setting consisted of seven hospital emergency departments in Seattle, WA. Hospitalized patients and medical examiners cases were included. The participants in the study were helmeted bicyclists who suffered a head injury or who damaged or hit their helmet in a crash. The Snell Memorial Foundation laboratory evaluated the helmets, blinded to crash circumstance and injury diagnosis. Damage was scored on a five-point scale (0 = none to 4 = destroyed). The damage location for each helmet was coded into regions (six longitudinal and three latitudinal) and mapped onto a three-dimensional CAD (computer-aided design) model of a helmet. The same procedure was also followed for injury location, which was mapped onto a three-dimensional ISO (International Organization for Standardization) headform for visualization of head-injury distribution. 785 helmeted subjects met the criteria for inclusion in the sub-study, and 527 helmets were purchased and evaluated (67%). 316 (60%) of the helmets had no or minimal damage, and 209 (39.7%) had significant damage (score 2, 3 or 4). Helmet types were 49.7% hard shell, 34.2% thin shell and 16.1% no shell. The risk of head and brain injury increased if the helmet was destroyed: OR = 5.3 (95% CI 2.9, 9.9) and OR = 11.2 (95% CI 3.5, 37.9), respectively. A high proportion of helmet impacts were along the front edge of the helmet, with a preponderance of head injuries in the same region. The large number of impacts to the front rim of the helmet, combined with the substantial number of riders with injuries to the forehead, indicate that some helmets, because of poor fit or wearing style, expose the forehead to injury. In addition, the data indicate that for a small proportion of injuries, the energy to the helmet may exceed design limits.

Accidents, Traffic↗
PubMed1997

Bike speed measurements in a recreational population: validity of self reported speed.

OBJECTIVE: Speed at the time of a bicycle crash is an important determinant of the amount of energy transmitted. Controlling for speed is thus important in the evaluation of outcomes and effectiveness of intervention strategies. This study was conducted to evaluate the accuracy of self reported speed in a population of recreational cyclists. METHODS: Children's and adults' bicycle speeds were measured with a radar gun as they rode along a closed road at weekend recreational events. Cyclists were then stopped and asked to estimate their speed. Measured speed, cyclist's estimate of their speed, age, and sex were documented. Parents were also asked to estimate their child's speed. RESULTS: One hundred and fifty two cyclists from 4 to 80 years of age participated. Seventy per cent were children 13 years of age or younger. The mean (SD) speed of this group was 8.9 (2.5) mph. Cyclists age 14 and older were traveling at a mean speed of 9.7 (2.87) mph. Estimated speeds were significantly higher than measured speeds for this older group, but there was no significant difference between mean measured and estimated speeds for the younger riders. There was also no significant difference between measured and estimated speed for males and females. Parents estimated their child's speed quite accurately. CONCLUSIONS: Self reported speeds for children were in close agreement with measured speeds and, thus, are sufficiently accurate to be a useful measure of crash severity in evaluating helmet effectiveness.

Adolescent↗
PubMed1997

Epidemiology of bicycle injuries and risk factors for serious injury.

OBJECTIVE: To determine the risk factors for serious injury to bicyclists, aside from helmet use. DESIGN: Prospective case-control study. SETTING: Seven Seattle area hospital emergency departments and two county medical examiner's offices. PATIENTS: Individuals treated in the emergency department or dying from bicycle related injuries. MEASUREMENTS: Information collected from injured bicyclists or their parents by questionnaire on circumstances of the crash; abstract of medical records for injury data. Serious injury defined as an injury severity score > 8. ANALYSIS: Odd ratios computed using the maximum likelihood method, and adjusted using unconditional logistic regression. RESULTS: There were 3854 injured cyclists in the three year period; 3390 (88%) completed questionnaires were returned 51% wore helmets at the time of crash. Only 22.3% of patients had head injuries and 34% had facial injuries. Risk of serious injury was increased by collision with a motor vehicle (odds ratio (OR) = 4.6), self reported speed > 15 mph (OR = 1.2), young age (< 6 years), and age > 39 years (OR = 2.1 and 2.2 respectively, compared with adults 20-39 years). Risk for serious injury was not affected by helmet use (OR = 0.9). Risk of neck injury was increased in those struck by motor vehicles (OR = 4.0), hospitalized for any injury (OR = 2.0), and those who died (OR = 15.1), but neck injury was not affected by helmet use. CONCLUSIONS: Prevention of serious bicycle injuries cannot be accomplished through helmet use alone, and may require separation of cyclists from motor vehicles, and delaying cycling until children are developmentally ready.

Adolescent↗
PubMed1997

MMR2 immunization at 4 to 5 years and 10 to 12 years of age: a comparison of adverse clinical events after immunization in the Vaccine Safety Datalink project. The Vaccine Safety Datalink Team.

BACKGROUND: The Advisory Committee on Immunization Practices recommends a second dose of measles, mumps, and rubella vaccine (MMR2) at age 4 to 5 years of age, whereas the American Academy of Pediatrics suggests MMR2 immunization at age 11 to 12 years of age. Because there is little information on whether the rate of adverse reactions to MMR2 immunization varies among these two age groups, we took advantage of differing immunization policies at two large HMOs to compare the frequency of clinical events after, and possibly related to, MMR2 immunization. METHODS: Information was collected on clinical events plausibly associated to MMR immunization (seizures, pyrexia, malaise/fatigue, nervous/musculoskeletal symptoms, rash, edema, induration/ecchymoses, lymphadenopathy, thrombocytopenia, aseptic meningitis, and joint pain) in two cohorts. At three facilities at Northern California Kaiser (Oakland, CA), 8514 children received MMR2 immunization at age 4 to 6 years of age; at Group Health Cooperative (Seattle, WA) 18 036 children received MMR2 immunization at age 10 to 12 years of age. To account for age-related differences in health care use, within each HMO, clinical events in a 30-day period after immunization were compared with a 30-day period before vaccination. RESULTS: Children 10 to 12 years of age were 50% more likely to have a clinical event after MMR2 immunization than in the period before immunization (odds ratio, 1.45; 95% confidence interval: 1.00,2.10). Children 4 to 6 years of age were less likely to have a visit for an event after immunization compared with the period before immunization (odds ratio, 0.64; 95% confidence interval: 0.40,1.01). CONCLUSIONS: These results suggest that the risk for clinical events after MMR2 immunizations is greater in the 10- to 12-year age group.

Adolescent↗
PubMed1997

Vaccine Safety Datalink project: a new tool for improving vaccine safety monitoring in the United States. The Vaccine Safety Datalink Team.

OBJECTIVE: To fill the large "gaps and limitations" in current scientific knowledge of rare vaccine adverse events identified in recent reviews of the Institute of Medicine. METHODS: Computerized information on immunization, medical outcomes, and potential confounders on more than 500 000 children 0 to 6 years of age is linked annually at several health maintenance organizations to create a large cohort for multiple epidemiologic studies of vaccine safety. RESULTS: Analysis of 3 years of follow-up data shows that 549 488 doses of diphtheria-tetanus-pertussis (DTP) and 310 618 doses of measles-mumps-rubella (MMR) vaccines have been administered to children in the study cohort. Analyses for associations between vaccines and 34 medical outcomes are underway. Screening of automated data shows that seizures are associated with receipt of DTP on the same day (relative risk [RR], 2.1; 95% confidence interval [CI], 1.1 to 4.0) and 8 to 14 days after receipt of MMR (RR, 3.0; 95% CI, 2.1 to 4.2). The diversity of vaccination exposures in this large cohort permits us to show that an apparent association of seizures 8 to 14 days after Haemophilus influenzae type b vaccine (RR, 1.6; 95% CI, 1.2 to 2.1) was attributable to confounding by simultaneous MMR vaccination; the association disappears with appropriate adjustment (RR, 1.0; 95% CI, 0.7 to 1.4). CONCLUSION: Preliminary design, data collection, and analytic capability of the Vaccine Safety Datalink project has been validated by replication of previous known associations between seizures and DTP and MMR vaccines. The diversity in vaccine administration schedules permits potential disentangling of effects of simultaneous and combined vaccinations. The project provides a model of public health-managed care collaborations in addition to an excellent infrastructure for safety and other studies of vaccines.

Adverse Drug Reaction Reporting Systems↗
PubMed1997

The association between the purchase of a handgun and homicide or suicide.

OBJECTIVES: The purpose of this study was to determine whether purchase of a handgun from a licensed dealer is associated with the risk of homicide or suicide and whether any association varies in relation to time since purchase. METHODS: A case-control study was done among the members of a large health maintenance organization. Case subjects were the 353 suicide victims and 117 homicide victims among the members from 1980 through 1992. Five control subjects were matched to each case subject on age, sex, and zip code of residence. Handgun purchase information was obtained from the Department of Licensing. RESULTS: The adjusted relative risk of suicide was 1.9 (95% confidence interval [CI] = 1.4, 2.5) for persons with a history of family handgun purchase from a registered dealer. The adjusted relative risk for homicide, given a history of family handgun purchase, was 2.2 (95% CI = 1.3, 3.7). For both suicide and homicide, the elevated relative risks persisted for more than 5 years after the purchase. CONCLUSIONS: Legal purchase of a handgun appears to be associated with a long-lasting increased risk of violent death.

Adolescent↗
PubMed1997

Injuries involving off-road cycling.

BACKGROUND: Data on injuries due to off-road bicycling are scarce, but do indicate that injuries in this sport are frequent. We examined the pattern of injuries to off-road riders as part of a larger study of bicycle injuries and helmet use. METHODS: We undertook a prospective study of bicycle-related injuries identified at seven emergency departments in Seattle, Washington, between March 1992 and August 1994. Hospitalized patients and medical examiners' cases were included. Detailed questionnaires and abstraction of all medical records provided information on crash and rider characteristics and injury type and severity. RESULTS: A total of 3390 injured riders participated, representing an 88% response rate. Of all injured cyclists, 127 (3.7%) were injured riding "off road." Seventy-three percent of off-road cyclists were 20 to 39 years of age, and 86.6% were male. Helmet use was 80.3% for off-road cyclists as compared with 49.5% for other cyclists. The number of head and face injuries for the off-road cyclists was only 40% of the number incurred by other cyclists. Four percent of off-road cyclists had severe injuries (injury Severity Score > 8), and 6.3% were hospitalized, compared with 6.8% and 9.4%, respectively, of other cyclists. CONCLUSIONS: The majority of off-road bicycling injuries are minor. Off-road cyclists are less likely to have head and face injuries than other cyclists and are more likely to wear helmets.

Accidents↗
PubMed1997

Mammography diffusion and trends in late-stage breast cancer: evaluating outcomes in a population.

The purpose of this study was to assess mammography diffusion in a population offered an organized breast cancer screening program, using intervals of 1-3 years, and to evaluate its effect on the late-stage cancer (tumors > or = 3 cm2) rates compared to rates in the surrounding community. We measured "ever-use" of mammography (1986-1992) among women enrollees of a consumer-controlled health care organization (n > or = 60,000/year; ages > or = 40), Group Health Cooperative of Puget Sound (GHC). Among these same women and the surrounding community (n = > or = 745,000/year), we measured late-stage cancer rates. Using unconditional logistic regression, we compared annual rates of ever-use among GHC women ages 40-49 and > or = 50 (1986-1992) and late-stage breast cancer (1983/84-1991/92) among all women. Among all GHC women ages 40 to 49, and 50 years of age and older, 67.4 and 82.8%, respectively, ever-used mammography by 1992. By 1992, approximately one-third of the mammograms among GHC women occurred in each of the three previous years. The rate of late-stage tumors declined significantly in the GHC and non-GHC populations among women 50 years of age and older (P < 0.001) but not among women ages 40 to 49. In conclusion, implementing a system of automated reminders was not sufficient to maximize mammography use in a population. Reductions in late-stage disease occurred among women ages > or = 50, even when regular" was not synonymous with "annual."

Adult↗