Biomedical subjects

R S Murray

Publications and source records attributed to R S Murray.

48 records · Page 3Linked to original sources

PubMed1983

Experience with the 'Triple Test' in pancreatic disease.

The results of the secretin-pancreozymin test, duodenal aspirate cytology and hypotonic duodenography (the Triple Test), performed during a single duodenal intubation in patients with pancreatic or ampullary carcinoma, chronic pancreatitis and non-pancreatic disease were analysed retrospectively. Thirty-five of 36 carcinoma patients and all 11 chronic pancreatitis patients had an abnormal result. One hundred and sixteen of 170 non-pancreatic disease patients had a normal result. It would appear that the Triple Test (TT) may be a useful screening test for pancreatic disease.

Cholecystokinin↗

PubMed1981

Pre-operative biliary drainage in patients with obstructive jaundice. A comparison of the percutaneous transhepatic and endoscopic transpapillary routes.

Pre-operative biliary drainage may reduce the mortality and morbidity associated with surgery in the patient with obstructive jaundice. It is possible to drain the bile duct via two routes pre-operatively The transhepatic route was used in 12 patients and the papillary route in 8. Only 1 patients died in the postoperative period. Transhepatic drainage was found suitable for routine use in patients with a dilated biliary tree, in particular in those with unresponsive cholangitis. Transpapillary drainage is not suitable for routine use but has a place in short-term drainage in patients with mild jaundice and cholangitis caused by gallstones in the bile duct.

Bile↗

PubMed1980

Patients appreciate premedication for endoscopy.

Upper gastrointestinal endoscopy without sedation by means of a small diameter (9 mm) instrument is feasible but patients often remember the procedure as unpleasant, do not wish to have it repeated, and compare it unfavourably with a barium meal. In contrast, endoscopy with a larger instrument (13 mm) after diazepam sedation is usually well tolerated and often regarded as no more uncomfortable than a barium meal. Even when a narrow instrument is used, patients still benefit from premedication with diazepam, although return to normal activity is slower because of drowsiness.

Barium Sulfate↗

PubMed1979

A prospective study of low back pain.

Consecutive patients attending hospital for the first time with backache were entered into a prospective study, provided that certain defined causes (infective, neoplastic, metabolic and inflammatory etc.) were not apparent at the first visit. Amongst 188 available for analysis, 65% were discharged and 28% defaulted, together making a total of 93% who 'recovered uneventfully' (in the sense that they were no longer attending hospital) on average in about three months, 4% came to 'myelography' (radiculography using Dimer-X or Amipaque) including 2% to discectomy, 1.5% proved to have treatable underlying diseases accounting for their backache while 1.5% became 'chronic attenders'. Information available at the first visit (patient characteristics, history, examination, radiographs and psychological questionnaire) provided few pointers to what the outcome would be or how long the patient would attend hospital. In particular, routine X-ray examination did not provide clues to any important conditions not already suspected by the clinicians. A case is made for reserving routine radiography for patients who have not recovered within about three months.

Adolescent↗

PubMed1979