Reciprocal ribose interactions: a possible structural motif in and between RNA's.
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Biomedical subjects
Publications and source records attributed to R S Morgan.
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Atomic absorption spectroscopy, electron microprobe analysis, and dithizone staining of trophozoites and cysts of Entamoeba invadens demonstrate that these cells have a high concentration of zinc (approximately 10(-6) microgram per cell or 1 percent of their dry weight). In the cysts of this organism, the zinc is confined to the chromatoid bodies, which previous work has shown to contain crystals of ribosomes. The chemical state and function of this zinc are unknown.
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A three-dimensional Fourier synthesis at an axial resolution of 75 angstroms of optical diffraction data from electron micrographs of stained sections of chromatoid bodies reveals the position of the large and small ribosomal subunits within these crystals of ribosomes.
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Optical Fourier transformns, made of electron mnicrographs of the crystalline array of ribonucleoprotein known as chromatoid bodies of Entamoeba invadens, have been interpreted as the transforms of a helix of 12 nodes in five turns. A model shows that this helix may be built of spheres 180 angstroms in diameter, placed at a radius of 150 angstroms. The optical transform of the model is very similar to the transform of the original electron micrograph.
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