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Biomedical subjects

R S Dhillon

Publications and source records attributed to R S Dhillon.

14 recordsLinked to original sources
PubMed2001

Co-existing granular cell tumor and adenocarcinoma of the lung: a case report and review of the literature.

Granular cell tumor (GCT) of the lung is a rare tumor, constituting less than 10% of all GCTs. It is a multicentric tumor and infiltrates into adjoining tissue, but malignant GCT of the lung has not been reported. Diagnosis is usually obtained with bronchoscopic biopsy. Treatment options include bronchoscopic extirpation, laser therapy, and sleeve resection. We present a case of GCT co-existing with adenocarcinoma of the lung and review the literature.

Adenocarcinoma, Bronchiolo-Alveolar↗
PubMed1994

Temporomandibular joint dislocation and deafness from a cricket ball injury.

Cricket is a national sport in some countries and can be potentially hazardous. We report an incident of a cricket ball impact to the chin, which resulted in posterior dislocation of both temporomandibular joints and bilateral mixed deafness. There appear to be no similar case reports in the literature.

Athletic Injuries↗
PubMed1994

Cervical necrotizing fasciitis and tonsillitis.

We present a case of cervical necrotizing fasciitis following quinsy in a previously fit and healthy man. This is a potentially fatal condition with few specific clinical signs that requires early diagnosis and surgical debridement. Other features of the disease are discussed.

Anti-Bacterial Agents↗
PubMed1989

Aesthetic surgery for microtia.

We describe here a technique for reconstruction of the external ear based upon an autogenous costal cartilage graft which is inserted into a cutaneous pocket dissected in the auricular area. Three subsequent procedures are then performed: rotation of the ear-lobe; reconstruction of the tragus; and elevation of the auricle. The ideal age for reconstruction is about 7 years. This technique was originally described by Brent, who has a very extensive experience with this kind of surgery. Skin deficiencies can be overcome by using either a temporo-parietal fascial flap or a skin expander.

Cartilage↗
PubMed1989

Parapharyngeal masses. Report de 4 cases.

The reduced incidence of inflammatory pathology in the head and neck over the last 20 years has diminished the clinical importance of the potential fascial spaces in this region. However, the parapharyngeal space, because of its contents, is still important. Lesions in this region have variable presentations and their management often requires a multidisciplinary approach. The anatomy of this space is the key to the understanding of the pathophysiological effects from expanding lesions occurring within it. We report 4 unusual cases to illustrate the management policy and highlight the pitfalls of lesions in this area.

Adult↗
PubMed1989

Craniofacial resection. An alternative incision and skull base repair.

Neoplasia of the superior group of paranasal sinuses (frontal, ethmoidal and sphenoidal) has an extremely poor prognosis. Resection, preceded or followed by radiotherapy offers a 5 year survival of less than 30% (1). Satisfactory surgical excision has been undermined by difficulties of access to the cribriform plate area, a common site for residual disease. Furthermore the practice of piecemeal removal invariably resulted in inadequate clearance. The craniofacial approach allows not only excellent access to the anterior skull base but also in bloc excision. The results of treating 7 patients with craniofacial resection for tumours in this area are presented. Particular reference is made to a horizontal forehead skin crease incision for intracranial access. A new technique using a combination of surgical, pericranium, partial thickness skin and fibrin glue to repair the skull base defect is described.

Adult↗
PubMed1988

The middle ear in cleft palate children pre and post palatal closure.

A multicentre prospective trial was commenced in July 1984 to establish the incidence of otitis media with effusion (OME) in children born with a cleft of the palate. Additionally, the data recorded would allow an assessment of the effect of palatal closure on middle ear function. Prior to palatal closure, 97% of ears in a group of 50 patients had otitis media with effusion (OME). The insertion of a long-term ventilation tube provided a means of aeration of one ear with the non-ventilated ear acting as a control. Eighty percent of control ears had persistent OME during a 24-month follow-up period post palatal repair. It would seem that OME is universally present in children with a cleft palate prior to 4 months of age and this incidence is only marginally diminished by palatal surgery. The liaison between plastic surgical and ENT units should be even closer than before in order to manage these patients satisfactorily.

Cleft Palate↗
PubMed1987

Posterior fossa ganglioglioma--an unusual cause of hearing loss.

Intracranial or spinal gangliogliomas of the CNS are rare tumours. Although several cases have been reported over the years, controversy still remains as to their origin, treatment and prognosis. A case of an eight-year-old girl with a ganglioglioma in the cerebellum with extension into the cerebello-pontine angle is described. The histological basis of the diagnosis is discussed and a review of the literature is presented.

Cerebellar Neoplasms↗
PubMed1984

Myasthenia gravis in otolaryngological practice.

A retrospective study of 48 unselected patients with myasthenia gravis was undertaken to evaluate the head and neck manifestations of this disease and to examine the role of the otolaryngologist in diagnosis and management. Oropharyngeal features were found in 56% of patients at presentation. In 20 the initial complaint was of one or more symptoms referable to the upper aerodigestive tract, whilst in 9 (18.8%) these were the only symptoms. The importance of maintaining a high index of clinical suspicion is emphasized, as the early muscle weakness is invariably mild and fluctuant. Contemporary aspects of the aetiology, diagnosis and management are considered. Particular attention is focused on the characteristics of the stapedius reflex in this disorder, as this is probably the most sensitive objective test for assessing defective neuromuscular transmission.

Adolescent↗
PubMed1984

Acoustic Neuroma Suspicion Index: an aid to investigation and diagnosis.

A clinical scale, the Acoustic Neuroma Suspicion Index (ANSI) is presented. It was based initially on the retrospective analysis of 397 patients suspected of having an acoustic neuroma of whom, following full investigation, 263 (66%) were found to have space occupying lesions. After minor modifications, the Index was re-tested on 98 patients of whom 56 proved to have tumors while 47, who did not, formed a control group. All tumor cases were confirmed surgically. Neuro-otological investigations can be expensive, time consuming and occasionally unpleasant for patients; furthermore they are not always readily available. Though the diagnosis of an acoustic tumor or other cerebellopontine angle lesion is often straightforward, atypicality of presentation occurs often. The ANSI uses simple selected data from the history and clinical examination, with routine audiological, vestibular and radiological investigations to calculate a score. If this score exceeds the predetermined threshold, further investigations should be undertaken.

Caloric Tests↗
PubMed1982

Rehabilitation after major head and neck surgery--the patients' view.

Forty-nine patients who were free of tumour 5 months to 14 years (mean 30 months) after total laryngectomy or a commando procedure were given questionnaires designed to obtain the patient's assessment of their resulting disability. Sixteen areas of disability were studied grouped under five main headings: speech, eating, cosmetic, employment and social. Following laryngectomy more than half of the patients achieved successful communication by oesophageal speech. Success in this was usually associated with minimal problems in other areas. The disabilities after commando procedures were more varied and complex. More patients reported severe disability in more than one area. Difficulties with chewing and swallowing were prominent. The results are illustrated with patients' comments. Ways in which rehabilitation might be improved are considered.

Adult↗
PubMedDate not supplied

Estimation of residues of carbofuran and its metabolites in sugarcane and soil by derivatization with 1-fluoro-2,4-dinitrobenzene and gas chromatography with nitrogen-phosphorus detection.

Residues of carbofuran and its metabolites were studied in sugarcane plants and soil after application at 1 and 2 kg/ha. The residues of carbofuran and its metabolites were extracted by refluxing with 0.25N HCI, partitioned into dichloromethane, and cleaned up on acidic alumina. The respective 7-phenols of carbofuran, 3-ketocarbofuran, and 3-hydroxycarbofuran were destroyed by treatment with ceric ammonium sulfate, and the residues were derivatized with 1-fluoro-2,4-dinitrobenzene. The derivatives were estimated by gas chromatography with nitrogen-phosphorus detection. The concentration of 3-hydroxycarbofuran in sugarcane plants remained higher and persisted longer than that of the parent compound. Carbofuran-derived residues were not detected in cane juice. Soil samples were found to contain only carbofuran, which declined at a very fast rate that followed a first-order kinetics rate of reaction.

Carbofuran↗