Immunoglobulin status of geriatric pulmonary tuberculosis patients of Himachal Pradesh.
Immunoglobulins (IgG, IgA & IgM) levels were estimated in 50 bacillary cases of geriatric pulmonary tuberculosis (PTB) and 25 healthy controls of comparable age group by single radial immunodiffusion technique. All Igs were raised in PTB cases, the rise being directly proportional to the radiological extent of disease. Exudative cases had more marked rise compared to patients with productive and fibrotic lesions. Those cases of PTB having associated COPD (28 cases), showed less marked increase in Igs and with treatment, Ig levels declined, the decline was slower in cases having associated COPD.