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Biomedical subjects

R S Bartholomew

Publications and source records attributed to R S Bartholomew.

At least 37 records · Page 2Linked to original sources

Fish hook injuries of the eye.

Two cases of fish hook injuries to the eye are described. Both were removed successfully by rotating the hook through undamaged tissue before snipping off the barb. Good vision was restored without complications for periods of 12 and 18 months.

Adult↗

Calcium oxalate crystals in the aqueous.

We found octohedral crystals in the aqueous of a patient with phacolytic glaucoma. They were identified as calcium oxalate by their physical and chemical characteristics.

Aqueous Humor↗

Glaucoma implants. Their use in difficult cases of glaucoma.

Implants with a regime of fibrosis suppression (prednisolone 30 mg daily plus fluphenamic acid 200 mg three times a day for 6 to 8 weeks) controlled the intraocular pressure (applanation tonometry (AT) less than 21 mm Hg) in seven out of ten patients with different types of glaucoma. One implant was removed after erosion of the conjunctiva and sclera; there were no other serious complications. Use of the implant is indicated after failed drainage operations or as a primary procedure in glaucoma associated with aphakia, chronic uveitis, vitreous in the anterior chamber, and scarring of the conjunctiva.

Adult↗

Spheroidal degeneration of the cornea. Prevalence and association with other eye diseases.

A sample of 2,427 South African Negroes of the Pondo tribe was specifically examined for spheroidal degeneration of the cornea (S.D.C.). The prevalence of S.D.C. was 7.0% for the whole sample. It was twice as prevalent in men (9.9%) as in women (4.3%) and the prevalence increased with age over 50 for both sexes. The risk of having developed Stage II and III S.D.C. increased with age for men but not for women. The risk of having developed Stage III S.D.C. was not related to age or sex. No significant associations were found between S.D.C. and pterygium, cortical or nuclear cataract and glaucoma (all types and absolute glaucoma). There was a significant association between S.D.C. and pseudocapsular exfoliation for elderly men but elderly men with arcus senilis were less likely to have developed S.D.C. Poor corneal nutrition or metabolism are possible aetiological factors in the progression of S.D.C. to Stages II and III.

Adult↗

Implants for draining neovascular glaucoma.

The implant design, surgical technique, and pharmacological methods of controlling bleb fibrosis, used to treat neovascular glaucoma, are described, together with the results of 14 operations performed on 12 eyes.

Aged↗

"Dye/light" Dye-induced photosensitization of herpes virus. A clinical trial on humans.

A series of 21 patients with herpetic corneal ulcers was treated by photodynamic inactivation (using a single application of neutral red 1 per cent solution followed by a 15-min exposure to a 40 watt light of 440--550 nm), carbolization, or idoxuridine (IDU) ointment. No significant difference was found in the number that healed, the mean healing time, or the number of recurrences after any of the three treatments.

Clinical Trials as Topic↗

Vicryl (polyglactin 910) in cataract surgery. A controlled trial.

In a controlled, randomized trial in 45 cataract operations a new synthetic absorbable suture (8-0 monofilament Vicryl, made by Ethicon), was compared with monofilament nylon or virgin silk normally used. There was a higher incidence of early complications-hyphaema, shallow anterior chamber, and choroidal detachment (15-4 per cent v. 0 per cent)-with the absorbable suture. But these differences were not significant at the 0-05 level and might well disappear with more operative experience, particularly the modified technique of knot-tying. In handling qualities Vicryl was superior to both 10-0 monofilament nylon and 8-0 virgin silk with the exception of knot-tying, in which it was inferior to 8-0 virgin silk. Vicryl is considered to be a useful absorbable suture in cataract surgery but knot-tying requires modification of technique.

Cataract Extraction↗

Sympathetic ophthalmitis. Successful treatment of late cases.

Three severe cases of sympathetic ophthalmitis, which presented late for treatment, are described. The response to prolonged treatment with systemic prednisolone was unexpectedly good, occurring as long as 70 days after starting treatment and continuing up to 16 months.

Adult↗

The Stryker turning frame in surgery of posterior displacement of the lens.

A Stryker turning frame was used during surgical removal of a posterior displaced lens. Its use had the following advantages over other methods: simplified management of the patient under general anaesthesia; constant stability of the eye and transfixing needle during the procedure and the maintenance of sterility in the operating area.

Female↗

Tape/slide course in ophthalmology for undergraduates.

A tape/slide course in ophthalmology was used for fifth year medical students at the University of Edinburgh. A statistical comparison between the tape/slide and lecture method of teaching showed no significant difference in examination results: means mark (P greater than 0-50), spread of mark (P greater than 0-05), or in question consistency (P greater than 0-40). The tape/slide method is initially time consuming to produce but has clear advantages in the long term, being of a consistently high standard, easy to present and repeat, useful in revision, for student electives and in lecturers' absence.

Audiovisual Aids↗