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Biomedical subjects

R Rutkowski

Publications and source records attributed to R Rutkowski.

At least 55 records · Page 3Linked to original sources
PubMed1978

Ferrographic analysis of wear particles in arthroplastic joints.

Analysis of aspirated synovial fluid appears to be a useful method for the study of the rates, mechanisms, and biological responses to wear in surgical joint replacements. Ferrography, an industrial technique of magnetic separation of particulate matter from samples of lubricating solutions, allows separation of wear debris from synovial fluid. Bichromatic microscopy and SEM X-ray analysis permit identification of metallic particles from arthroplastic joints. Polarized light microscopy characterizes and differentiates polyethylene and polymethacrylate debris. The number and morphology of the wear particles in synovial specimens from arthroplastic joints correlate with the rate and the mechanisms of wear, as confirmed by examination of the implant and the adjacent synovial tissue.

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PubMed1978

Experimental fracture healing: evaluation using radionuclide bone imaging: concise communication.

Radionuclide bone imaging was performed in a rabbit model to observe the course of fracture healing and to establish criteria for distinguishing nonunion and delayed healing from normal healing. Sequential gamma-camera images (with pinhole collimator) were collected and subjected to computer analysis. Five groups were established: a) control--immobilization; b) control--immobilization plus periosteal stripping; c) simple fracture--osteotomy; d) delayed union--osteotomy plus periosteal stripping; and e) nonunion--osteotomy, periosteal stripping and polymethyl methacrylate interposed between fracture fragments. Histographic representation of absolute count rates along rabbit tibias followed a predictable pattern in the simple-fracture and delayed-union groups. They differed only in the time of appearance of phases. The nonunion group demonstrated no recognizable sequential pattern. In this experimental model, serial bone scanning with quantitative data analysis has shown potential for indicating the course of healing in fractures and for serving as a guide to treatment.

Animals↗
PubMedDate not supplied

[A study of involuntary treatment in psychiatric hospitals].

Research revealed that the only documented form of forced treatment was the use of mechanical restraining of patients. The frequency and circumstances of restraining patients were highly dependent on, among others, the structure of employment of hospital personnel. Research was conducted on 6962 patients from 6 psychiatric hospitals. It was revealed that during a month mechanical restraint was used with 5.5% of the patients. This percentage wavered from 1.6% to 8% in different hospitals. Isolation was not used at all. The frequency and circumstances of using force was significantly related to age, sex, marital status, the length of hospitalization and the diagnosis of the patient. Furthermore, the number of staff and the structure of employment in particular hospitals was important.

Female↗
PubMedDate not supplied

[Effect of calcium channel blockers on histamine liberation from isolated basophils and bronchial reactivity in patients with bronchial asthma].

An effect of verapamil and nifedipine on the cellular histamine release and non-specific reactivity of the bronchi measured with methacholine test was studied. In vitro tests were carried out in basophils isolated from 19 asthmatic patients. Reactivity of the bronchi was investigated in 5 patients. Both verapamil and nifedipine significantly inhibited histamine release from the cells in vitro in all examined concentrations (10(-7)-10(-4) M) while a single dose of these drugs administered to the asthmatic patients did not exert a significant effect on the airway constriction in vivo.

Administration, Inhalation↗
PubMedDate not supplied

[Influence of pirenzepine on bronchial reactivity evaluated by the methacholine provocation test in a double-blind study of patients with bronchial asthma].

A double blind study was carried out on the effect of pirenzepine on bronchial reactivity assessed by metacholine provocation. The study was carried out on 19 patients with bronchial asthma. Bronchial provocation tests was performed according to the method of Ryan et al using the DeVilbis 646 nebuliser coupled to the Rosenthal--French dosimeter. Spirometric parameters were assessed using Vitalograph. The results show a significant protective effect of pirenzepine on bronchial spasm induced by metacholine.

Adult↗