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Biomedical subjects

R Russo

Publications and source records attributed to R Russo.

At least 217 records · Page 12Linked to original sources

On the differential nature of implicit and explicit memory.

In this article, we report two experiments that provide further evidence concerning the differential nature of implicit and explicit memory. In Experiment 1, subjects first undertook a sentence-verification task. While carrying out this task, half of the subjects were also required to carry out a secondary processing task involving tone monitoring. Twenty-four hours later, the subjects' memory for target items in the sentence-verification task was tested explicitly by means of a recognition task and implicitly by examining the extent to which the items primed fragment completion. Recognition performance was significantly impaired by the imposition of secondary processing demands during the original learning phase. In contrast, fragment completion was completely unaffected by this additional processing, even though substantial priming was observed. In Experiment 2, we examined whether priming in fragment completion is influenced by the nature of repetition during initial learning. Subjects studied a list of target items that were each repeated twice. Half the items were repeated immediately (lag 0) and half were repeated after six intervening items (lag 6). Memory for the items was assessed by recognition and by priming in fragment completion. Recognition was affected by lag, with lag 6 items being recognized better than lag 0 items. However, although significant priming was obtained, the extent of this priming was uninfluenced by lag. These data indicate two additional dimensions along which implicit and explicit memory differ and, furthermore, they support recent conceptualizations of processing differences underlying these two forms of memory.

Adult↗

[Vector cardiography features of right ventricular activation delays: nosologic classification and clinical correlation].

Electrovectorcardiographic features of 150 patients showing right ventricular activation delays (RVAD) has been analyzed. This analysis of RAVD, especially for type I, which is the group with the widest morphologic variability, has permitted a more detailed classification: a type I with 5 subtypes, a type II with 1 subtype, a type III and an intermediate type between type II and III. Fifty-five per cent of the patients were included in type I and its variant and most were classified, often without cardiac disease, as belonging to the classic type I. Thirty per cent of RVAD were of type II; 12% of type III and the remaining were in the intermediate group between type II and III. The various morphologies, moreover, were correlated with the clinical picture: the classic type I was never seen in subjects with cardiac disease, while the others types and subtypes were present either in subjects with cardiac disease or in elderly subjects, also without relevant pathologies (senile heart, especially, the type IA") or in otherwise healthy subjects. In a medical-social context, checking for RVAD, in the absence of cardiac disease, might usefully avoid further investigation. It is underlined the usefulness of this correlation for clinical prognostic judgement.

Adolescent↗

The surgical treatment of recurrent anterior dislocation of the shoulder.

The authors analysed the results obtained in 94 recurrent dislocations of the shoulder submitted to surgery between 1979 and 1988 according to the Latarjet method. After considering the reasons for selecting this method, they discuss some aspects of the physiopathology of recurrent dislocation and instability of the shoulder. the principles of the Latarjet method are described and the Patte modification, used by the authors since 1986, is briefly illustrated. The long-term results were evaluated according to the walch and Duplay evaluation scheme. Sixty-nine patients with a follow-up ranging from a minimum of 1 year to a maximum of 9 were reviewed. The results were excellent or good in 93% of the cases.

Biomechanical Phenomena↗

Synthesis and physicochemical characterization of a new material (PUPA) based on polyurethane and poly(amido-amine) components capable of strongly adsorbing quantities of heparin.

The synthesis of new materials (PUPAs) based on a commercial polyurethane and a heparin-complexing polymer, poly(amido-amine), was studied. PUPAs are capable of adsorbing heparin because the basic nitrogens of poly(amido-amine), once protonated, interact with the negative charges carried by the heparin molecule. Six different samples of PUPA were synthesized having a varied ratio of the components. The quantity of basic nitrogen on the surface and the bound heparin for each sample was determined. Two different kinds of heparin are present on a PUPA surface: one is strongly bound but can be detached by 0.1 M NaOH solution, the other is physically adsorbed and is slowly released by a stream of saline solution. A relationship between the quantity of strongly bound heparin and basic nitrogen was found. SEM and FTIR-ATR analysis were performed on all the PUPA samples. The mechanical characteristics change according to chemical composition.

Adsorption↗

Cancer risk in a cohort of licensed pesticide users.

First admissions to the hospital among 25,945 men living in southern Piedmont and holding a license authorizing them to use pesticides were analyzed in a study of the cancer risk related to exposure to pesticides. Standardized incidence ratios significantly higher than one were encountered for malignant skin cancers and lymphomas. The risk of lymphoma was particularly high in predominantly arable areas. The standardized incidence ratios for tumors of the nervous system and hematopoietic tissue showed an interesting age-related pattern and a higher risk in areas primarily devoted to forest tree plantation, but did not reach significance. Certain hypotheses are advanced to explain these findings.

Aged↗

[A method for evaluating the hepatitis B vaccination program].

Two mathematical models have been created in order to estimate the effectiveness (number and proportion of infections saved) and the cost/effectiveness ratio (cost per infection saved) of a hepatitis B vaccination strategy among hospital personnel. The aim of the models is to analyse the mathematical relationship between the measurement of strategy impact and some variables: theoretical effectiveness of vaccine, proportion of assent to the programme, epidemiological characteristics. Applying models to Piedmont situation it has been possible to identify factors which have negatively influenced the effectiveness and efficiency of strategy.

Cost-Benefit Analysis↗

[The non-depolarizing myorelaxants in orotracheal intubation. A clinical comparison].

The present study was designed to compare the rapidity of onset of neuromuscular blockade after administration of 5 different neuromuscular relaxants (succinylcholine, d-tubocurarine, pancuronium, atracurium and vecuronium) in 75 patients, randomly allocated in 5 treatment groups. The facilitation for endotracheal intubation was evaluated using a clinical score. The for onset relaxation was shorter when using succinylcholine. Among non-depolarizing relaxants an adequate facilitation for endotracheal intubation was observed, two minutes after administration of atracurium and vecuronium, while endotracheal intubation was difficult when using d-tubocuranine and pancuronium.

Adult↗

[Diagnosis of delayed upper left ventricular activation: limits of electrocardiography and usefulness of vectorcardiography].

The electrocardiographic (ECG) diagnosis of delayed ventricular left superior activation (DVLSA) is often difficult and uncertain, even when all the criteria proposed in clinical literature are fulfilled. The vectorcardiography (VCG) always permits an accurate diagnostic evaluation because the contour of the QRS loop describes successively the various phases of ventricular depolarization. Sensitivity and specificity of ECG in diagnosing DVLSA have been calculated referring to VCG analysis. The QRS loop initial forces orientation in the frontal plane, a VCG highly reliable criterion, was considered especially significant for this purpose. The sensitivity and specificity of ECG were, respectively, 75% and 95%. Moreover, this study has confirmed the low performance of frontal plane QRS axis criterion and the necessity of polyparametric method for a correct ECG-VCG diagnosis of DVLSA. However, the VCG is more reliable than ECG in such diagnosis because it allows thoroughly to analyze QRS-loop initial forces.

Adult↗

Immune response to anti-HBV vaccination: study of conditioning factors.

The Authors studied the immune responses of 691 health care workers who were given HEVAC B vaccine (455 subjects) and HB Vax vaccine (216 subjects). The immune responses were correlated with data obtained by questionnaires: age, sex, B.M.I., drinking habits, smoking. The results showed correlation between these variables and immune response to vaccine.

Adult↗

The functional response of Toxorhynchites rutilus rutilus to changes in the population density of its prey Aedes aegypti.

We present an analysis of the functional response of the predator Toxorhynchites rutilus rutilus (Coquillett) to changes in the density of the larvae of Aedes aegypti (L.) (Diptera: Culicidae). The experiment was replicated for five different ages, and at three different densities of the predator. The data were fitted to Rogers' (1972) random predator equation by non-linear least-squares in order to estimate searching efficiency and handling time for each experimental treatment. The data show that estimated searching efficiencies are highest at intermediate ages of the predator for all predator densities tested. Handling time declines exponentially with increasing predator age. There is a marked interference effect; searching efficiency decreases with increased predator density, and this is most pronounced at intermediate prey ages. Estimated handling times increase with predator density at a rate which declines with increasing predator age.

Aedes↗

Effect of central serotonin depletion on blood pressure and the renin system in rats.

In the present study we examined the effect of depletion of central nervous system serotonin by 5,7-dihydroxytryptamine on blood pressure in male Wistar rats. We also analyzed the relationship between the serotonergic and renin-angiotensin systems. Blood pressure was determined before and after intracisternal administration of 5,7-dihydroxytryptamine, 200 micrograms in saline with 1 mg/ml ascorbic acid (n = 9). Control rats (n = 8) received intracisternal vehicle. Before sacrifice, blood and cerebrospinal fluid samples were obtained. The brain was dissected in several areas. Serotonin, norepinephrine, angiotensinogen, and reninlike concentrations were determined in the brain parenchyma; angiotensinogen concentration was evaluated in cerebrospinal fluid and plasma samples; plasma renin activity was also measured. Treatment produced a significant decrease in blood pressure (-10 mm Hg; p less than 0.025) and, simultaneously, a high depletion of serotonin stores in the studied central areas (p less than 0.001), except in the cerebral cortex. Reninlike concentration was increased in the medulla oblongata (p less than 0.005) and the brainstem (p less than 0.02) after 5,7-dihydroxytryptamine treatment. Angiotensinogen concentration was decreased in the hypothalamus and elevated in the spinal cord. Angiotensinogen concentration in cerebrospinal fluid, plasma angiotensinogen concentration, and plasma renin activity did not change with treatment. Serotonin concentration in the cerebrospinal fluid remained unchanged, while the 5-hydroxyindoleacetic acid level was diminished (-47%; p less than 0.001). Intracisternal administration of 5,7-dihydroxytryptamine produced a hypotensive effect in normal rats and several modifications of the renin-angiotensin complex, suggesting a relationship between the monoaminergic and peptidergic systems.

5,7-Dihydroxytryptamine↗

T-wave changes in patients with hemodynamic evidence of systolic or diastolic overload of the left ventricle: a retrospective study on 168 patients with isolated chronic aortic valve disease.

The effect of systolic and diastolic overload of the left ventricle on the T wave was studied in 86 patients with pure aortic stenosis and in 82 patients with pure aortic insufficiency documented by hemodynamic investigation. All patients had hemodynamically significant, chronic isolated aortic valve disease with electrocardiographic evidence of left ventricular hypertrophy (Sokolow index greater than or equal to 45 mm). All had undergone selective coronary angiography. Flattened or negative T waves were present in 44 patients with aortic stenosis (51%) and in 66 (80%) with aortic incompetence. Inversion of the T wave in left ventricular leads was unrelated to the presence of ventricular conduction disturbances or to coronary artery disease or to low cardiac index. It was significantly related to older age (P = 0.0001) and, in patients with aortic incompetence, to the end-diastolic volume (P = 0.04). Digitalis intake was a nonsignificant (P = 0.10) independent variable. These findings suggest that patients with aortic stenosis cannot be distinguished from patients with aortic incompetence by the electrocardiogram and that the theory of Cabrera and Monroy is not valid in this set of patients.

Adult↗