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Biomedical subjects

R Rupp

Publications and source records attributed to R Rupp.

At least 37 records · Page 2Linked to original sources
PubMed1997

Orthodontic management of impacted maxillary cuspids.

Many problems have been associated with the eruption of maxillary canines and careful supervision and early diagnosis of disturbances in eruption are portentous. A review of the literature concerning the impaction and treatment of the maxillary cuspids, followed by a case report, is presented. Incidence of impactions; most frequent location of impactions; common treatment for impactions; and etiology are discussed. Risks involved are enumerated. A case report of impacted maxillary cuspids utilizing a two-phase treatment (Sagittal II, Wilson 3D quad action, and straight wire appliance) is presented.

Cephalometry↗
PubMed1996

Ratings of students' performances in a third-year internal medicine clerkship: a comparison between problem-based and lecture-based curricula.

PURPOSE: To compare clinical performances in a third-year medicine clerkship between studies from a problem-based learning (PBL) curriculum and students from a traditional, lecture-based learning (LBL) curriculum. METHOD: The study participants were 88 PBL students and 364 LBL students rotating through a common third-year internal medicine clerkship at the Bowman Gray School of Medicine at Wake Forest University, classes of 1991-1995. Faculty and housestaff assessed the students' performances using four clinical rating scales. The student also completed the medicine student ("shelf") test of the National Board of Medical Examiners (NBME). RESULTS: On average, the PBL students received significantly higher ratings from housestaff and faculty on all four rating scales. No difference in scores on the NBME medicine shelf test was observed. CONCLUSION: The results support the hypothesis that preclinical PBL curricula as found at the Bowman Gray School of Medicine may enhance third-year students' clinical performances.

Achievement↗
PubMed1995

Root resorption related to orthodontics and other factors: a review of the literature.

Each patient (and parents or guardian) should be clearly informed that there is a real possibility of one or more teeth undergoing root resorption during orthodontic procedures. They should sign an Information and Consent Form arranged by the dentist that they understand these risks before treatment is begun. Open bite cases possess significantly great degrees of resorption. Since trauma is closely associated with root resorption, the patient (and parents or guardian) should be questioned concerning previous traumatic occurrences that involved blows or accidents involving the teeth. Periapical radiographs are an important part of orthodontic records. They are useful to compare pretreatment and posttreatment root resorption. Maxillary incisors are affected more frequently and to a greater degree than the rest of the teeth during active treatment. Also, root resorption of the upper incisors during the initial 6-9 months of treatment with fixed appliances gives a high risk for continued resorption during the subsequent treatment. Therefore, it would be prudent to take periapical radiographs periodically during treatment. When root resorption is detected during active treatment, a decision must be made as to whether to continue, modify or discontinue the treatment. Extremely heavy forces should be avoided, since they have been shown to produce greater resorption activity. The ectopic eruption of canines causes a significant number of resorptions in lateral incisors. Habits adversely affect root resorption and should be eliminated if possible. Pathological lesions increase the risk of resorption. Periodontal disease increases the risk of resorption. The practitioner contemplating doing orthodontics should be cognizant of the above factors in evaluating the risk of root resorption. Patients (and parents or guardians) should be made clearly aware that any type of orthodontic treatment carries with it the risk of root tip blunting or resorption during orthodontic therapy.

Child↗
PubMed1993

Magnetic resonance imaging evaluation of the spine with metal implants. General safety and superior imaging with titanium.

We studied the cases of 15 patients who underwent postoperative magnetic resonance imaging evaluation after being treated with metal spinal implants. Spine stabilization was required in traumatic injuries for eight patients, cancer destruction in four patients, late cervical subluxation in one patient, spondylosis in one patient, and spondylolisthesis in one patient. A variety of stainless steel and titanium spinal implants were used. The images were evaluated for spinal and implant positioning and artifact production. Both stainless steel and titanium implants were imaged safely and there was no evidence of implant migration of local tissue-heating effect. The titanium spinal implants allowed postoperative spine imaging without the significant image distortion characteristic of the stainless steel implants. The stainless steel implants created significant artifact that impaired the usefulness of the magnetic resonance imaging evaluation.

Adult↗
PubMed1993

Adolescent Children of Alcoholics.

Children from families with an alcoholic member are at increased risk of emotional, cognitive, behavioral, social, medical, and substance abuse problems. The authors review the characteristics of such children and the factors that increase their vulnerability; discuss the problems of codependency and enabling; and explore clinical presentations and treatment issues for both adolescent children of alcoholics and their families.

Journal Article↗
PubMed1991

The myoD gene family: nodal point during specification of the muscle cell lineage.

The myoD gene converts many differentiated cell types into muscle. MyoD is a member of the basic-helix-loop-helix family of proteins; this 68-amino acid domain in MyoD is necessary and sufficient for myogenesis. MyoD binds cooperatively to muscle-specific enhancers and activates transcription. The helix-loop-helix motif is responsible for dimerization, and, depending on its dimerization partner, MyoD activity can be controlled. MyoD senses and integrates many facets of cell state. MyoD is expressed only in skeletal muscle and its precursors; in nonmuscle cells myoD is repressed by specific genes. MyoD activates its own transcription; this may stabilize commitment to myogenesis.

Animals↗
PubMed1975

Endogenous Candida endophthalmitis leading to bilateral corneal perforation.

A premature neonate developed advanced bilateral endophthalmitis before the significance of underlying Candida sepsis was appreciated. Severe endophthalmitis resulted in corneal thinning, descemetocele formation, and perforation. The infection occurred in the clinical setting of broad-spectrum antibiotic therapy and indwelling intravenous catheters. Cultures of blood and catheter tips had been positive for Candida but were not considered significant until advanced ocular infection was noted. The septic process resulted in the infant's death after systemic amphotericin B therapy was discontinued because of renal toxicity.

Amphotericin B↗