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Biomedical subjects

R Rosso

Publications and source records attributed to R Rosso.

At least 379 records · Page 21Linked to original sources
PubMed1983

Neurilemmoma of the ciliary body: report of a case.

A case of ciliary body neurilemmoma is described. This neoplasm is extremely rare in the uveal tract and has been reported only once in the ciliary body. After extensive clinical studies of the rapidly growing tumour enucleation was performed. Subsequent histological examination showed typical features of highly vascular benign neurilemmoma. The main clinical and pathological features are reported and diagnostic problems are discussed.

Adult↗
PubMed1982

Randomized trial of chemoimmunotherapy in advanced non-oat-cell lung cancer.

Thirty patients without any prior chemotherapy and histologically proved non-oat-cell advanced lung cancer entered a randomized trial comparing a combination chemotherapeutic regimen (cyclophosphamide, methotrexate, BCNU) and the same combination plus intradermic BCG. Twenty-nine patients were evaluable for survival. Mean survival was 11 and 3.5 months for chemotherapy and chemoimmunotherapy group, respectively. The difference was statistically significant (P less than 0.025). A tumor enhancement can be postulated. Skin tests before treatment (PPD, Candida, Varidase) seem to be prognostic for survival.

Adenocarcinoma↗
PubMed1981

Estrogen-like action of tamoxifen on vaginal epithelium in breast cancer patients.

The action of prolonged administration of Tamoxifen on the vaginal epithelium in postmenopausal breast cancer patients has been investigated by means of exfoliative cytology. Our study gives quite convincing evidence of a clear-cut estrogenic effect of Tamoxifen on vaginal epithelium. The relationship between estrogenic properties of Tamoxifen and breast cancer management is discussed.

Age Factors↗
PubMed1979

Combination chemotherapy with vinblastine, bleomycin and methotrexate in DTIC-resistant metastatic melanoma.

Fifteen patients with metastatic DTIC-resistant malignant melanoma were treated with vinblastine, bleomycin and methotrexate combination chemotherapy. Three patients showed an objective response (one complete response). The therapy was well tolerated and easy to administer. This combination appears to produce in DTIC-resistance patients a response rate similar to that obtained with DTIC.

Adult↗
PubMed1977

Mitochondrial abnormalities in some human muscular diseases and in experimental ischemic myopathy.

Morphologic abnormalities have been observed in two cases of human polymyositis and in three cases of ocular myopathies. Similar findings can be observed in experimental ischemic myopathy. "Ragged red" fibres, with anomalous distribution of oxidative enzymes, mitochondrial alterations, with presence of intracristal paracrystalline inclusions and degenerative myofibrillar changes are the similar features. The similarity between some of these alterations, expecially mitochondrial changes, is remarkable, but it is difficult to correlate them to the primary etiology of described human myopathies.

Adult↗