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Biomedical subjects

R Rosenthal

Publications and source records attributed to R Rosenthal.

137 records · Page 8Linked to original sources
PubMedDate not supplied

Cervical lymphadenitis--a rare case of focal listeriosis.

Cervical lymphadenopathy is a condition with a broad differential diagnosis. Malignant tumors, allergic reactions, autoimmune diseases as well as various infectious agents can be the cause. We report the case of a 75-year-old man who had a cervical lymphadenopathy without symptoms of infection. The draining lymph nodes were excised. Histology revealed a granulomatous abscess and culture yielded pure growth of Listeria monocytogenes. Because food is occasionally contaminated with L. monocytogenes, the pathogenesis of this condition may be similar to that of lymph node tuberculosis.

Aged↗
PubMedDate not supplied

Statistical power: concepts, procedures, and applications.

This paper discusses the concept of statistical power and its application to psychological research. Power, the probability that a significance test will produce a significant result when the null hypothesis is false, often is neglected with potentially serious consequences. The concept of power should be considered as part of planning and interpreting research. This article provides explication of the concept of power and suggestions for researchers to increase the power of their investigations.

Behavior Therapy↗
PubMedDate not supplied

Context effects in forensic science: a review and application of the science of science to crime laboratory practice in the United States.

This article discusses the phenomenon of "context effects" by reviewing the findings and practices of a range of scientific fields, including astronomy, physics, biology, medicine, and especially the relevant research and theory from psychology. Context information, such as expectations about what one is supposed to see or conclude, has been found to have a small but relentless impact on human perception, judgment, and decision-making. The article then considers the vulnerability of forensic science practice to context effects, and concludes by suggesting that forensic science adopt practices familiar in other fields of scientific work, in particular blind or double-blind testing and also the use of evidence line-ups.

Forensic Medicine↗
PubMedDate not supplied

Effect size, practical importance, and social policy for children.

Real decisions for real children are influenced by the papers developmentalists write, regardless of whether we ever intended our papers to be used in the policy arena. Yet most social scientists seldom analyze data in ways that are most useful to policymakers. The primary purpose of this paper is to share three ideas concerning how to evaluate the practical importance of a finding or set of findings. First, for research to be most useful not only in the policy arena but also more generally, significance tests need to be accompanied by effect size estimates. The practical importance of an effect size depends on the scientific context (i.e., measurement, design, and method) as well as the empirical literature context. Second, researchers need to use all existing data when weighing in on a policy debate; here, meta-analyses are particularly useful. Finally, researchers need to be careful about embracing null or small findings, because effects may well be small due to measurement problems alone, particularly early in the history of a research domain.

Child↗
PubMedDate not supplied

Psychiatric symptom severity and length of stay on an intensive rehabilitation unit.

The purpose of this study was to evaluate the role of psychiatric symptoms in the medical and surgical rehabilitation of patients on an intensive rehabilitation unit and to examine whether psychiatric symptom severity contributes to length of hospital stay (LOS). Forty-four patients (21 men and 23 women) were assessed at admission and before discharge with the Functional Independence Measure (FIM). Subjects were evaluated with the Mini-Mental State Exam (MMSE), the Hamilton Rating Scale for Depression (Ham-D), Positive and Negative Symptom Scale, (PANSS), and Scale for the Assessment of Negative Symptoms (SANS). Thirty-six percent of subjects were cognitively impaired (MMSE < 25), 14% had significant depressive symptoms (Ham-D > 12), and 52% had significant negative symptomatology (PANSS-N > 15). A regression analysis yielded a model of three predictive factors. Gender, the PANSS General subscale, and the SANS Attention subscale accounted for 42.4% of LOS variance. These results indicate that psychiatric symptoms are common in medical rehabilitation inpatients and, together with demographic factors, are associated with increased LOS.

Adult↗
PubMedDate not supplied

Tri-Nasal triamcinolone acetonide nasal spray 200 and 400 micrograms qd versus placebo and Nasacort triamcinolone acetonide nasal aerosol 440 micrograms qd in patients suffering from seasonal allergic rhinitis during the grass season.

Tri-Nasal Nasal Spray is an investigational solution of triamcinolone acetonide (TAA) currently being evaluated as a treatment for allergic rhinitis. The safety and efficacy of 200 and 400 micrograms once daily doses of Tri-Nasal Nasal Spray, an active control (440 micrograms once daily of Nasacort Nasal aerosol), and Tri-Nasal Nasal Spray placebo were compared over a 2-week treatment period in a double-blind (the Nasacort treatment was not blinded), parallel design trial. A total of 377 adult patients in 13 centers were enrolled during the grass pollen season. The primary efficacy variable was the weekly average of the SSI (Symptom Severity Index), the sum of daily nasal congestion, rhinorrhea, and sneezing severity scores from the patient diary. A total of 355 patients completed the study. All active treatments were significantly more effective than placebo in relieving nasal symptoms at each treatment week. The 400 micrograms Tri-Nasal Nasal Spray and Nasacort treatments had a rapid onset of action, demonstrating significant improvement in the SSI versus placebo by the second day of treatment. Results for the individual nasal symptoms and other secondary efficacy measures paralleled those of the primary efficacy variables. Tri-Nasal Nasal Spray and Nasacort were comparable in safety, and in treating the nonocular symptoms of seasonal allergic rhinitis.

Administration, Intranasal↗